UB Paderborn / Katalog / Suche / in CDI

1 – 25 von 215

Sortiert nach

PI3K inhibitors are finally coming of age

Nature reviews. Drug discovery, 2021-10, Vol.20 (10), p.741-769

2021

Link zum Volltext

Verfügbarkeit prüfen

Design, Synthesis, and Biological Evaluation of MEK PROTACs

Journal of medicinal chemistry, 2020-01, Vol.63 (1), p.157-162

2020

Link zum Volltext

Verfügbarkeit prüfen

Author Correction: PI3K inhibitors are finally coming of age

Nature reviews. Drug discovery, 2021-10, Vol.20 (10), p.798-798

2021

Link zum Volltext

Verfügbarkeit prüfen

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Journal of medicinal chemistry, 2014-03, Vol.57 (6), p.2746-2754

2014

Link zum Volltext

Verfügbarkeit prüfen

Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases

Journal of medicinal chemistry, 2019-05, Vol.62 (10), p.4783-4814

2019

Link zum Volltext

Verfügbarkeit prüfen

Structural and conformational determinants of macrocycle cell permeability

Nature chemical biology, 2016-12, Vol.12 (12), p.1065

2016

Link zum Volltext

Verfügbarkeit prüfen

Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors

Journal of medicinal chemistry, 2018-06, Vol.61 (12), p.5435-5441

2018

Link zum Volltext

Verfügbarkeit prüfen

A class of highly selective inhibitors bind to an active state of PI3Kγ

Nature chemical biology, 2019-04, Vol.15 (4), p.348

2019

Link zum Volltext

Verfügbarkeit prüfen

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction

ACS chemical biology, 2020-04, Vol.15 (4), p.1026-1035

2020

Link zum Volltext

Verfügbarkeit prüfen

Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration

Journal of medicinal chemistry, 2017-06, Vol.60 (12), p.5057-5071

2017

Link zum Volltext

Verfügbarkeit prüfen

High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants

Heart rhythm, 2020-03, Vol.17 (3), p.492-500

2020

Link zum Volltext

Verfügbarkeit prüfen

Spiro-fused Pyrrolidine, Piperidine, and Oxindole Scaffolds from Lactams

Organic letters, 2012-09, Vol.14 (18), p.4846-4849

2012

Link zum Volltext

Verfügbarkeit prüfen

14-3-3 modulation of the inflammatory response

Pharmacological research, 2021-01, Vol.163, p.105236-105236, Article 105236

2021

Link zum Volltext

Verfügbarkeit prüfen

Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes

Journal of molecular and cellular cardiology, 2016-11, Vol.100, p.25-34

2016

Link zum Volltext

Verfügbarkeit prüfen

Designing novel building blocks is an overlooked strategy to improve compound quality

Drug discovery today, 2015-01, Vol.20 (1), p.11-17

2015

Link zum Volltext

Verfügbarkeit prüfen

Surprising lipophilicity observations identify unexpected conformational effects

Bioorganic & medicinal chemistry letters, 2022-08, Vol.69, p.128786, Article 128786

2022

Link zum Volltext

Verfügbarkeit prüfen

Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction

Journal of medicinal chemistry, 2022-12, Vol.65 (24), p.16818-16828

2022

Link zum Volltext

Verfügbarkeit prüfen

Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction”

Journal of medicinal chemistry, 2023-02, Vol.66 (3), p.2205-2207

2023

Link zum Volltext

Verfügbarkeit prüfen

A Practical Method for Targeted Library Design Balancing Lead-like Properties with Diversity

ChemMedChem, 2009-05, Vol.4 (5), p.800-808

2009

Link zum Volltext

Verfügbarkeit prüfen

On the absolute configuration of 1-cyclopropylethan-1-amine

Tetrahedron: asymmetry, 2017-09, Vol.28 (9), p.1135-1138

2017

Link zum Volltext

Verfügbarkeit prüfen

[3 + 2] Cycloaddition Reactions of 4-Alkyl-3-hydroxy-2H-pyrazolo[4,3-c]iso- quinolinium Inner Salts

Journal of organic chemistry, 2003-10, Vol.68 (22), p.8700-8703

2003

Link zum Volltext

Verfügbarkeit prüfen

Stereocontrol during the alkylation of enolates attached to .pi.-allyl-Mo(CO)2Cp systems

Journal of the American Chemical Society, 1990-10, Vol.112 (22), p.8034-8042

1990

Link zum Volltext

Verfügbarkeit prüfen

Somatostatin inhibits high conductance colonic apical potassium channels via G protein-dependent tyrosine dephosphorylation

Gastroenterology (New York, N.Y. 1943), 2001-04, Vol.120 (5), p.A313-A313

2001

Link zum Volltext

Verfügbarkeit prüfen

[3 + 2] cycloaddition reactions of 4-alkyl-3-hydroxy-2H-pyrazolo[4,3-c]isoquinolinium inner salts

Journal of organic chemistry, 2003-10, Vol.68 (22), p.8700-8703

2003

Link zum Volltext

Verfügbarkeit prüfen

1 – 25 von 215

Suche als RSS-Feed

Aktive Filter

KollektionEZB Free E-Journals

KollektionTaylor & Francis Current Content Access

PublikationsformTagungsberichte

ThemaAdult

ThemaBiological And Medical Sciences

Nur zeigenGeprüft (Peer-Review)

Suchergebnisse filtern

Filter anzeigen

Nur zeigen

Mit Volltextzugriff
(178)

Publikationsform

Sprache

Englisch
(215)
Japanisch
(29)

Erscheinungsjahr

n.n

Thema

15 weitere anzeigen...

Weniger anzeigen...

Zeitschrift / Serie

5 weitere anzeigen...

Weniger anzeigen...

Neu hinzugefügt

... seit 30 Tagen
(2)
... seit 90 Tagen
(5)

Menü

Weitere Dienste

Einstellungen

PI3K inhibitors are finally coming of age

Design, Synthesis, and Biological Evaluation of MEK PROTACs

Author Correction: PI3K inhibitors are finally coming of age

Impact of Stereospecific Intramolecular Hydrogen Bonding on Cell Permeability and Physicochemical Properties

Evolution of PI3Kγ and δ Inhibitors for Inflammatory and Autoimmune Diseases

Structural and conformational determinants of macrocycle cell permeability

Discovery of Highly Isoform Selective Orally Bioavailable Phosphoinositide 3‑Kinase (PI3K)‑γ Inhibitors

A class of highly selective inhibitors bind to an active state of PI3Kγ

Discovery of AZD8154, a Dual PI3Kγδ Inhibitor for the Treatment of Asthma

Identification of Phosphate-Containing Compounds as New Inhibitors of 14-3-3/c-Abl Protein–Protein Interaction

Design and Synthesis of Soluble and Cell-Permeable PI3Kδ Inhibitors for Long-Acting Inhaled Administration

High-throughput phenotyping of heteromeric human ether-à-go-go-related gene potassium channel variants can discriminate pathogenic from rare benign variants

Spiro-fused Pyrrolidine, Piperidine, and Oxindole Scaffolds from Lactams

14-3-3 modulation of the inflammatory response

Convergence of models of human ventricular myocyte electrophysiology after global optimization to recapitulate clinical long QT phenotypes

Designing novel building blocks is an overlooked strategy to improve compound quality

Surprising lipophilicity observations identify unexpected conformational effects

Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction

Correction to “Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3‑3 Protein–Protein Interaction”

A Practical Method for Targeted Library Design Balancing Lead-like Properties with Diversity

On the absolute configuration of 1-cyclopropylethan-1-amine

[3 + 2] Cycloaddition Reactions of 4-Alkyl-3-hydroxy-2H-pyrazolo[4,3-c]iso- quinolinium Inner Salts

Stereocontrol during the alkylation of enolates attached to .pi.-allyl-Mo(CO)2Cp systems

Somatostatin inhibits high conductance colonic apical potassium channels via G protein-dependent tyrosine dephosphorylation

[3 + 2] cycloaddition reactions of 4-alkyl-3-hydroxy-2H-pyrazolo[4,3-c]isoquinolinium inner salts

Aktive Filter

Suchergebnisse filtern