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hERG K(+) channels: structure, function, and clinical significance

Physiological reviews, 2012-07, Vol.92 (3), p.1393-1478

2012

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Warm body temperature facilitates energy efficient cortical action potentials

PLoS computational biology, 2012-04, Vol.8 (4), p.e1002456-e1002456

2012

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Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology

eLife, 2023-12, Vol.12

2023

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The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

Nature communications, 2016-06, Vol.7 (1), p.11984-11984, Article 11984

2016

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Arrhythmogenic effects of ultra-long and bistable cardiac action potentials

PLoS computational biology, 2021-02, Vol.17 (2), p.e1008683-e1008683

2021

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Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia

Stem cell research & therapy, 2023-07, Vol.14 (1), p.183-183

2023

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The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review

Annals of noninvasive electrocardiology, 2023-01, Vol.28 (1), p.e13015-n/a

2023

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Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels

Cell, 2010-06, Vol.141 (6), p.1018-1029

2010

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Multiple Interactions between Cytoplasmic Domains Regulate Slow Deactivation of Kv11.1 Channels

The Journal of biological chemistry, 2014-09, Vol.289 (37), p.25822-25832

2014

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Structural Dynamics of the MscL C-terminal Domain

Scientific reports, 2017-12, Vol.7 (1), p.17229-11, Article 17229

2017

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A constricted opening in Kir channels does not impede potassium conduction

Nature communications, 2020-06, Vol.11 (1), p.3024-13, Article 3024

2020

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Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities

Frontiers in pharmacology, 2018-09, Vol.9, p.1035-1035

2018

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The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating

PloS one, 2012-02, Vol.7 (2), p.e31640-e31640

2012

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Getting to the heart of hERG K+ channel gating

The Journal of physiology, 2015-06, Vol.593 (12), p.2575-2585

2015

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Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction

Progress in biophysics and molecular biology, 2008-10, Vol.98 (2-3), p.137-148

2008

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Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions

Biochemical journal, 2013-08, Vol.454 (1), p.69-77

2013

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In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details

Frontiers in physiology, 2017-11, Vol.8, p.934-934

2017

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Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels

The Journal of general physiology, 2012-09, Vol.140 (3), p.293-306

2012

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Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes

Molecular therapy. Methods & clinical development, 2023-09, Vol.30, p.459-473

2023

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Electrophoretic transfer protein zymography

Analytical biochemistry, 2011-04, Vol.411 (2), p.277-283

2011

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Biophysics in the time of COVID

Biophysical reviews, 2022-02, Vol.14 (1), p.13-14

Hill, Adam P.

2022

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Boosting the reserves: additive regulation of cardiac repolarisation

The Journal of physiology, 2017-04, Vol.595 (7), p.2269-2270

Hill, Adam P.

2017

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A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer

Wellcome open research, 2020-01, Vol.5, p.152-152

2020

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C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels

PloS one, 2013-10, Vol.8 (10), p.e77032-e77032

2013

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Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk

JACC. Basic to translational science, 2017-10, Vol.2 (5), p.575-590

2017

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hERG K(+) channels: structure, function, and clinical significance

Warm body temperature facilitates energy efficient cortical action potentials

Assessing drug safety by identifying the axis of arrhythmia in cardiomyocyte electrophysiology

The role of MscL amphipathic N terminus indicates a blueprint for bilayer-mediated gating of mechanosensitive channels

Arrhythmogenic effects of ultra-long and bistable cardiac action potentials

Development of a robust induced pluripotent stem cell atrial cardiomyocyte differentiation protocol to model atrial arrhythmia

The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review

Domain Reorientation and Rotation of an Intracellular Assembly Regulate Conduction in Kir Potassium Channels

Multiple Interactions between Cytoplasmic Domains Regulate Slow Deactivation of Kv11.1 Channels

Structural Dynamics of the MscL C-terminal Domain

A constricted opening in Kir channels does not impede potassium conduction

Experimentally Validated Pharmacoinformatics Approach to Predict hERG Inhibition Potential of New Chemical Entities

The S4-S5 linker acts as a signal integrator for HERG K+ channel activation and deactivation gating

Getting to the heart of hERG K+ channel gating

Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction

Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions

In Vitro and In Silico Risk Assessment in Acquired Long QT Syndrome: The Devil Is in the Details

Voltage-sensing domain mode shift is coupled to the activation gate by the N-terminal tail of hERG channels

Development of new adeno-associated virus capsid variants for targeted gene delivery to human cardiomyocytes

Electrophoretic transfer protein zymography

Biophysics in the time of COVID

Boosting the reserves: additive regulation of cardiac repolarisation

A nonlinear and time-dependent leak current in the presence of calcium fluoride patch-clamp seal enhancer

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels

Endocardial TRPC-6 Channels Act as Atrial Mechanosensors and Load-Dependent Modulators of Endocardial/Myocardial Cross-Talk

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