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Editorial for the Special Issue: “Targeting β-Lactamases to Fight Bacterial Resistance to β-Lactam Antibiotics”

Antibiotics (Basel), 2020-05, Vol.9 (6), p.290

Pozzi, Cecilia

2020

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Iron Biomineral Growth from the Initial Nucleation Seed in L‐Ferritin

Chemistry : a European journal, 2020-05, Vol.26 (26), p.5770-5773

2020

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Chemistry at the protein–mineral interface in L-ferritin assists the assembly of a functional (μ³-oxo)Tris[(μ²-peroxo)] triiron(III) cluster

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.2580-2585

2017

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The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders

Journal of biological inorganic chemistry, 2018-12, Vol.23 (8), p.1219-1226

2018

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Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin

Chemistry : a European journal, 2021-10, Vol.27 (59), p.14690-14701

2021

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Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)

Molecules (Basel, Switzerland), 2019-04, Vol.24 (8), p.1638

2019

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Structural Basis of Parasitic HSP90 ATPase Inhibition by Small Molecules

Pharmaceuticals (Basel, Switzerland), 2022-10, Vol.15 (11), p.1341

2022

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Detailed experimental and numerical characterization of turbulent flow in components of a water treatment plant

Water science and technology, 2019-12, Vol.80 (11), p.2117-2130

2019

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Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities

Molecules (Basel, Switzerland), 2019-03, Vol.24 (7), p.1257

2019

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Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design

International journal of molecular sciences, 2022-11, Vol.23 (22), p.14218

2022

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Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor

International journal of molecular sciences, 2022-08, Vol.23 (16), p.9458

2022

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Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer's Disease

Life (Basel, Switzerland), 2021-04, Vol.11 (5), p.386

2021

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Time-lapse anomalous X-ray diffraction shows how Fe2+ substrate ions move through ferritin protein nanocages to oxidoreductase sites

Acta crystallographica. Section D, Biological crystallography., 2015-04, Vol.71 (4), p.941-953

2015

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Validation of Recombinant Chicken Liver Bile Acid Binding Protein as a Tool for Cholic Acid Hosting

Biomolecules (Basel, Switzerland), 2021-04, Vol.11 (5), p.645

2021

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Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors

Molecules (Basel, Switzerland), 2019-04, Vol.24 (7), p.1362

2019

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Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase

Pharmaceuticals (Basel, Switzerland), 2021-06, Vol.14 (7), p.636

2021

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Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (45), p.18424-18429

2011

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In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I

Molecules (Basel, Switzerland), 2017-12, Vol.22 (12), p.2166

2017

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Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (34), p.E542-E549

2011

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Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases

Pharmaceuticals (Basel, Switzerland), 2021-11, Vol.14 (12), p.1246

2021

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Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

Cancers, 2021-04, Vol.13 (9), p.2061

2021

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Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R

Biomolecules (Basel, Switzerland), 2019-04, Vol.9 (4), p.134

2019

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Editorial for the Special Issue: "Targeting ([beta]-Lactamases to Fight Bacterial Resistance to ([beta]-Lactam Antibiotics"

Antibiotics (Basel), 2020-06, Vol.9 (6)

Pozzi, Cecilia

2020

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The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease

Acta crystallographica. Section F, Structural biology communications, 2015-08, Vol.71 (8), p.986-992

2015

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Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

Journal of medicinal chemistry, 2020-03, Vol.63 (6), p.2789-2801

2020

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Editorial for the Special Issue: “Targeting β-Lactamases to Fight Bacterial Resistance to β-Lactam Antibiotics”

Iron Biomineral Growth from the Initial Nucleation Seed in L‐Ferritin

Chemistry at the protein–mineral interface in L-ferritin assists the assembly of a functional (μ³-oxo)Tris[(μ²-peroxo)] triiron(III) cluster

The structure of the human glutaminyl cyclase–SEN177 complex indicates routes for developing new potent inhibitors as possible agents for the treatment of neurological disorders

Iron Binding in the Ferroxidase Site of Human Mitochondrial Ferritin

Targeting Methyltransferases in Human Pathogenic Bacteria: Insights into Thymidylate Synthase (TS) and Flavin-Dependent TS (FDTS)

Structural Basis of Parasitic HSP90 ATPase Inhibition by Small Molecules

Detailed experimental and numerical characterization of turbulent flow in components of a water treatment plant

Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities

Exploiting ELIOT for Scaffold-Repurposing Opportunities: TRIM33 a Possible Novel E3 Ligase to Expand the Toolbox for PROTAC Design

Structural Characterization of Human Heat Shock Protein 90 N-Terminal Domain and Its Variants K112R and K112A in Complex with a Potent 1,2,3-Triazole-Based Inhibitor

Dynamic Interplay between Copper Toxicity and Mitochondrial Dysfunction in Alzheimer's Disease

Time-lapse anomalous X-ray diffraction shows how Fe2+ substrate ions move through ferritin protein nanocages to oxidoreductase sites

Validation of Recombinant Chicken Liver Bile Acid Binding Protein as a Tool for Cholic Acid Hosting

Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors

Evidence of Pyrimethamine and Cycloguanil Analogues as Dual Inhibitors of Trypanosoma brucei Pteridine Reductase and Dihydrofolate Reductase

Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design

In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I

Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase

Repurposing the Trypanosomatidic GSK Kinetobox for the Inhibition of Parasitic Pteridine and Dihydrofolate Reductases

Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

Evidence of Destabilization of the Human Thymidylate Synthase (hTS) Dimeric Structure Induced by the Interface Mutation Q62R

Editorial for the Special Issue: "Targeting ([beta]-Lactamases to Fight Bacterial Resistance to ([beta]-Lactam Antibiotics"

The soluble Y115E-Y117E variant of human glutaminyl cyclase is a valid target for X-ray and NMR screening of inhibitors against Alzheimer disease

Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- and Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections

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