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Novel Latency Reversal Agents for HIV-1 Cure

Annual review of medicine, 2018-01, Vol.69, p.421

2018

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A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

Nature communications, 2018-11, Vol.9 (1), p.4811-16, Article 4811

2018

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BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency

Cell host & microbe, 2015-09, Vol.18 (3), p.345-353

2015

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Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV

International journal of molecular sciences, 2020-10, Vol.21 (20), p.7741

2020

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Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

Cell reports (Cambridge), 2017-01, Vol.18 (5), p.1324-1334

2017

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Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal

Antimicrobial agents and chemotherapy, 2018-11, Vol.62 (11)

2018

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Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration

Proceedings of the National Academy of Sciences - PNAS, 2013-02, Vol.110 (6), p.E448-E457

2013

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Reduced monocyte proportions and responsiveness in convalescent COVID-19 patients

Frontiers in immunology, 2023, Vol.14, p.1329026-1329026

2023

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A rapid and affordable point of care test for antibodies against SARS-CoV-2 based on hemagglutination and artificial intelligence interpretation

Scientific reports, 2021-12, Vol.11 (1), p.24507-24507, Article 24507

2021

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HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function

Frontiers in immunology, 2016-09, Vol.7, p.356-356

2016

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SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition

mBio, 2018-05, Vol.9 (3)

2018

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Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions

Virology journal, 2021-01, Vol.18 (1), p.1-1, Article 1

2021

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Dual TLR2 and TLR7 agonists as HIV latency-reversing agents

JCI insight, 2018-10, Vol.3 (19)

2018

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No evidence of severe acute respiratory syndrome–coronavirus 2 in semen of males recovering from coronavirus disease 2019

Fertility and sterility, 2020-06, Vol.113 (6), p.1135-1139

2020

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Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity

Viruses, 2022-10, Vol.14 (10), p.2288

2022

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Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS

Frontiers in immunology, 2021-06, Vol.12, p.682182

2021

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Hydroxychloroquine for treatment of non‐hospitalized adults with COVID‐19: A meta‐analysis of individual participant data of randomized trials

Clinical and translational science, 2023-03, Vol.16 (3), p.524-535

2023

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Bioactive Compounds from Euphorbia usambarica Pax. with HIV-1 Latency Reversal Activity

Pharmaceuticals (Basel, Switzerland), 2021-07, Vol.14 (7), p.653

2021

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Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo

Cell reports. Medicine, 2020-06, Vol.1 (3), p.100037-100037, Article 100037

2020

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Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients

Antimicrobial agents and chemotherapy, 2015-10, Vol.59 (10), p.5984-5991

2015

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Urinary Tract Infections: Current and Emerging Management Strategies

Clinical infectious diseases, 2013-09, Vol.57 (5), p.719-724

2013

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Sex Influences SAMHD1 Activity and Susceptibility to Human Immunodeficiency Virus-1 in Primary Human Macrophages

The Journal of infectious diseases, 2019-02, Vol.219 (5), p.777-785

2019

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Circulating Monocytes Are Not a Major Reservoir of HIV-1 in Elite Suppressors

Journal of Virology, 2011-10, Vol.85 (19), p.10399-10403

2011

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A Pilot Study Assessing the Safety and Latency-Reversing Activity of Disulfiram in HIV-1–Infected Adults on Antiretroviral Therapy

Clinical infectious diseases, 2014-03, Vol.58 (6), p.883-890

2014

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Novel Latency Reversal Agents for HIV-1 Cure

A majority of HIV persistence during antiretroviral therapy is due to infected cell proliferation

BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency

Interferon-Mediated Long Non-Coding RNA Response in Macrophages in the Context of HIV

Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation

Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal

Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration

Reduced monocyte proportions and responsiveness in convalescent COVID-19 patients

A rapid and affordable point of care test for antibodies against SARS-CoV-2 based on hemagglutination and artificial intelligence interpretation

HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function

SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition

Neutralization assay with SARS-CoV-1 and SARS-CoV-2 spike pseudotyped murine leukemia virions

Dual TLR2 and TLR7 agonists as HIV latency-reversing agents

No evidence of severe acute respiratory syndrome–coronavirus 2 in semen of males recovering from coronavirus disease 2019

Host Cell Redox Alterations Promote Latent HIV-1 Reactivation through Atypical Transcription Factor Cooperativity

Activation of the Anti-Oxidative Stress Response Reactivates Latent HIV-1 Through the Mitochondrial Antiviral Signaling Protein Isoform MiniMAVS

Hydroxychloroquine for treatment of non‐hospitalized adults with COVID‐19: A meta‐analysis of individual participant data of randomized trials

Bioactive Compounds from Euphorbia usambarica Pax. with HIV-1 Latency Reversal Activity

Pharmacological Activation of Non-canonical NF-κB Signaling Activates Latent HIV-1 Reservoirs In Vivo

Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients

Urinary Tract Infections: Current and Emerging Management Strategies

Sex Influences SAMHD1 Activity and Susceptibility to Human Immunodeficiency Virus-1 in Primary Human Macrophages

Circulating Monocytes Are Not a Major Reservoir of HIV-1 in Elite Suppressors

A Pilot Study Assessing the Safety and Latency-Reversing Activity of Disulfiram in HIV-1–Infected Adults on Antiretroviral Therapy

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

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