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HIV-associated chronic immune activation

Immunological reviews, 2013-07, Vol.254 (1), p.78-101

2013

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Natural SIV Hosts: Showing AIDS the Door

Science (American Association for the Advancement of Science), 2012-03, Vol.335 (6073), p.1188-1193

2012

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IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

Nature communications, 2021-05, Vol.12 (1), p.2866-2866, Article 2866

2021

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SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

Nature communications, 2021-02, Vol.12 (1), p.1282-1282, Article 1282

2021

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Understanding and targeting inflammation in SARS-CoV-2 and HIV infections

Free radical biology & medicine, 2022-08, Vol.189, p.11-12

Paiardini, Mirko

2022

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The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence

PLoS pathogens, 2022-07, Vol.18 (7), p.e1010723-e1010723

2022

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Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

PLoS pathogens, 2010-08, Vol.6 (8), p.e1001052-e1001052

2010

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Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription

PLoS pathogens, 2020-09, Vol.16 (9), p.e1008821-e1008821

2020

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Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

The Journal of clinical investigation, 2009-12, Vol.119 (12), p.3556-3572

2009

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Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

PLoS pathogens, 2016-02, Vol.12 (2), p.e1005412-e1005412

2016

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Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

PLoS pathogens, 2023-10, Vol.19 (10), p.e1011660-e1011660

2023

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Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4⁺ T cells, and disease progression

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (12), p.E1480-E1489

2015

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Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency

PLoS pathogens, 2023-11, Vol.19 (11), p.e1011755-e1011755

2023

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Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches

Frontiers in immunology, 2020-03, Vol.11, p.519-519

2020

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CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy

PloS one, 2020-01, Vol.15 (1), p.e0227124-e0227124

2020

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004467-e1004467

2014

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Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

Journal of Virology, 2010-08, Vol.84 (15), p.7886-7891

2010

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Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

PLoS pathogens, 2021-08, Vol.17 (8), p.e1009825-e1009825

2021

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Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies

Frontiers in immunology, 2018-04, Vol.9, p.780-780

2018

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Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

The Journal of clinical investigation, 2022-04, Vol.132 (8), p.1-17

2022

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Activated CD4⁺CCR5⁺ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

Proceedings of the National Academy of Sciences - PNAS, 2015-01, Vol.112 (2), p.518-523

2015

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HIV-associated chronic immune activation

Natural SIV Hosts: Showing AIDS the Door

IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8 + cells

SIV-induced terminally differentiated adaptive NK cells in lymph nodes associated with enhanced MHC-E restricted activity

Recommendations for measuring HIV reservoir size in cure-directed clinical trials

CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption

Understanding and targeting inflammation in SARS-CoV-2 and HIV infections

The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription

Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

Timing of initiation of anti-retroviral therapy predicts post-treatment control of SIV replication

Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4⁺ T cells, and disease progression

Preferential selection of viral escape mutants by CD8+ T cell 'sieving' of SIV reactivation from latency

Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches

CD4 rate of increase is preferred to CD4 threshold for predicting outcomes among virologically suppressed HIV-infected adults on antiretroviral therapy

CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells

Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART

Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19

Lymph Node Cellular and Viral Dynamics in Natural Hosts and Impact for HIV Cure Strategies

Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy

Activated CD4⁺CCR5⁺ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques

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