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Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

Cell, 2013-10, Vol.155 (3), p.540-551

2013

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HIV-1 Integration Landscape during Latent and Active Infection

Cell, 2015-01, Vol.160 (3), p.420-432

2015

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In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure

Annual review of pathology, 2022-01, Vol.17, p.271

2022

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Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay

PLoS pathogens, 2013-05, Vol.9 (5), p.e1003398-e1003398

2013

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New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

Nature medicine, 2014-04, Vol.20 (4), p.425-429

2014

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Recent developments in the search for a cure for HIV-1 infection: Targeting the latent reservoir for HIV-1

Journal of allergy and clinical immunology, 2014-07, Vol.134 (1), p.12-19

2014

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Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003174

2013

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Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

Nature (London), 2015-01, Vol.517 (7534), p.381-385

2015

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Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (11), p.E2575-E2584

2018

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Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods

PLoS pathogens, 2022-09, Vol.18 (9), p.e1010845-e1010845

2022

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CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells

PloS one, 2014-10, Vol.9 (10), p.e110731-e110731

2014

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Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

Journal of Virology, 2011-06, Vol.85 (12), p.6060-6064

2011

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Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques

Nature communications, 2022-06, Vol.13 (1), p.3463-3463, Article 3463

2022

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Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough

Cell host & microbe, 2008-08, Vol.4 (2), p.134-146

2008

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Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005679-e1005679

2016

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Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors

Journal of Virology, 2007-03, Vol.81 (5), p.2508-2518

2007

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Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4+ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy

Journal of Virology, 2009-09, Vol.83 (17), p.8470-8481

2009

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Kinetics of Human Immunodeficiency Virus Type 1 Decay following Entry into Resting CD4+ T Cells

Journal of Virology, 2005-02, Vol.79 (4), p.2199-2210

2005

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Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model

Journal of Virology, 2011-06, Vol.85 (11), p.5384-5393

2011

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Resting CD4+ T Cells from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals Carry Integrated HIV-1 Genomes within Actively Transcribed Host Genes

Journal of Virology, 2004-06, Vol.78 (12), p.6122-6133

2004

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Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

PLoS computational biology, 2019-04, Vol.15 (4), p.e1006849-e1006849

2019

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Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy

PloS one, 2016-08, Vol.11 (8), p.e0160192-e0160192

2016

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Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to Cure

The Journal of infectious diseases, 2021-02, Vol.223 (Supplement_1), p.S13-S21

2021

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HIV cure: The daunting scale of the problem

Science (American Association for the Advancement of Science), 2024-02, Vol.383 (6684), p.703-705

2024

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Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

HIV-1 Integration Landscape during Latent and Active Infection

In Vivo Dynamics of the Latent Reservoir for HIV-1: New Insights and Implications for Cure

Rapid quantification of the latent reservoir for HIV-1 using a viral outgrowth assay

New ex vivo approaches distinguish effective and ineffective single agents for reversing HIV-1 latency in vivo

Recent developments in the search for a cure for HIV-1 infection: Targeting the latent reservoir for HIV-1

Comparative analysis of measures of viral reservoirs in HIV-1 eradication studies

Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations

HIV-1 persistence following extremely early initiation of antiretroviral therapy (ART) during acute HIV-1 infection: An observational study

Expanded cellular clones carrying replication-competent HIV-1 persist, wax, and wane

Measuring the latent reservoir for HIV-1: Quantification bias in near full-length genome sequencing methods

CD4+ and CD8+ T cell activation are associated with HIV DNA in resting CD4+ T cells

Disulfiram Reactivates Latent HIV-1 in a Bcl-2-Transduced Primary CD4+ T Cell Model without Inducing Global T Cell Activation

Therapeutic efficacy of combined active and passive immunization in ART-suppressed, SHIV-infected rhesus macaques

Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough

Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions

Isolation and Characterization of Replication-Competent Human Immunodeficiency Virus Type 1 from a Subset of Elite Suppressors

Analysis of Human Immunodeficiency Virus Type 1 Viremia and Provirus in Resting CD4+ T Cells Reveals a Novel Source of Residual Viremia in Patients on Antiretroviral Therapy

Kinetics of Human Immunodeficiency Virus Type 1 Decay following Entry into Resting CD4+ T Cells

Influence of Host Gene Transcription Level and Orientation on HIV-1 Latency in a Primary-Cell Model

Resting CD4+ T Cells from Human Immunodeficiency Virus Type 1 (HIV-1)-Infected Individuals Carry Integrated HIV-1 Genomes within Actively Transcribed Host Genes

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Anti-HIV Antibody Responses and the HIV Reservoir Size during Antiretroviral Therapy

Low Inducibility of Latent Human Immunodeficiency Virus Type 1 Proviruses as a Major Barrier to Cure

HIV cure: The daunting scale of the problem

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