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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

Nature (London), 2015-03, Vol.519 (7542), p.247-250

2015

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Murder or not? Cold temperature makes criminals appear to be cold-blooded and warm temperature to be hot-headed

PloS one, 2014-04, Vol.9 (4), p.e96231-e96231

2014

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The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites

Nature communications, 2022-05, Vol.13 (1), p.2567-2567, Article 2567

2022

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Community guidelines for GPCR ligand bias: IUPHAR review 32

British journal of pharmacology, 2022-07, Vol.179 (14), p.3651-3674

2022

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Structure-based development of a subtype-selective orexin 1 receptor antagonist

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (30), p.18059-18067

2020

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Docking screens: right for the right reasons?

Current topics in medicinal chemistry, 2009-06, Vol.9 (9), p.755

2009

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Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment

Nature communications, 2024-02, Vol.15 (1), p.1831-1831

2024

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Reply to: How carvedilol does not activate β2-adrenoceptors

Nature communications, 2023-11, Vol.14 (1), p.7867-7867, Article 7867

2023

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Automatic and Efficient Decomposition of Two-Dimensional Structures of Small Molecules for Fragment-Based High-Throughput Docking

Journal of medicinal chemistry, 2006-12, Vol.49 (25), p.7384-7392

2006

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Docking and chemoinformatic screens for new ligands and targets

Current opinion in biotechnology, 2009-08, Vol.20 (4), p.429-436

2009

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How Carvedilol activates β2-adrenoceptors

Nature communications, 2022-11, Vol.13 (1), p.7109-20, Article 7109

2022

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Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor

eLife, 2021-12, Vol.10

2021

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Differential interaction patterns of opioid analgesics with µ opioid receptors correlate with ligand-specific voltage sensitivity

eLife, 2023-11, Vol.12

2023

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Guava (Psidium guajava) Fruit Extract Prepared by Supercritical CO2 Extraction Inhibits Intestinal Glucose Resorption in a Double-Blind, Randomized Clinical Study

Nutrients, 2019-07, Vol.11 (7), p.1512

2019

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An open source pharma roadmap

PLoS medicine, 2017-04, Vol.14 (4), p.e1002276-e1002276

2017

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Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists

PloS one, 2012, Vol.7 (11), p.e49910-e49910

2012

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In Vitro Measurements of Cellular Forces and their Importance in the Lung—From the Sub- to the Multicellular Scale

Life (Basel, Switzerland), 2021-07, Vol.11 (7), p.691

2021

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Micropatterning of Cells on Gold Surfaces for Biophysical Applications

STAR protocols, 2020-12, Vol.1 (3), p.100106-100106, Article 100106

2020

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Impact of Global Climate Change on the European Barley Market Requires Novel Multi-Method Approaches to Preserve Crop Quality and Authenticity

Foods, 2021-07, Vol.10 (7), p.1592

2021

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Der Bezirk Unterfranken 1852-1918: 1. Auflage

Kolb, Peter

2016

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On the construction of LIECE models for the serotonin receptor 5-HT[Formula: see text]R

Journal of computer-aided molecular design, 2023-07, Vol.37 (7), p.313-323

2023

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On the construction of LIECE models for the serotonin receptor 5-HT2AR

Journal of computer-aided molecular design, 2023-07, Vol.37 (7), p.313-323

2023

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On the construction of LIECE models for the serotonin receptor 5-HT\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$_{\text {2A}}$$\end{document}2AR

Journal of computer-aided molecular design, 2023-01, Vol.37 (7), p.313-323

2023

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Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3

Journal of medicinal chemistry, 2023-11, Vol.66 (21), p.15025-15041

2023

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Allosteric modulation of GPCRs: From structural insights to in silico drug discovery

Pharmacology & therapeutics (Oxford), 2022-09, Vol.237, p.108242-108242, Article 108242

2022

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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

Murder or not? Cold temperature makes criminals appear to be cold-blooded and warm temperature to be hot-headed

The pocketome of G-protein-coupled receptors reveals previously untargeted allosteric sites

Community guidelines for GPCR ligand bias: IUPHAR review 32

Structure-based development of a subtype-selective orexin 1 receptor antagonist

Docking screens: right for the right reasons?

Cryo-EM structure of cell-free synthesized human histamine 2 receptor/Gs complex in nanodisc environment

Reply to: How carvedilol does not activate β2-adrenoceptors

Automatic and Efficient Decomposition of Two-Dimensional Structures of Small Molecules for Fragment-Based High-Throughput Docking

Docking and chemoinformatic screens for new ligands and targets

How Carvedilol activates β2-adrenoceptors

Disentangling bias between Gq, GRK2, and arrestin3 recruitment to the M3 muscarinic acetylcholine receptor

Differential interaction patterns of opioid analgesics with µ opioid receptors correlate with ligand-specific voltage sensitivity

Guava (Psidium guajava) Fruit Extract Prepared by Supercritical CO2 Extraction Inhibits Intestinal Glucose Resorption in a Double-Blind, Randomized Clinical Study

An open source pharma roadmap

Limits of ligand selectivity from docking to models: in silico screening for A(1) adenosine receptor antagonists

In Vitro Measurements of Cellular Forces and their Importance in the Lung—From the Sub- to the Multicellular Scale

Micropatterning of Cells on Gold Surfaces for Biophysical Applications

Impact of Global Climate Change on the European Barley Market Requires Novel Multi-Method Approaches to Preserve Crop Quality and Authenticity

Der Bezirk Unterfranken 1852-1918: 1. Auflage

On the construction of LIECE models for the serotonin receptor 5-HT[Formula: see text]R

On the construction of LIECE models for the serotonin receptor 5-HT2AR

Development of Fluorescent AF64394 Analogues Enables Real-Time Binding Studies for the Orphan Class A GPCR GPR3

Allosteric modulation of GPCRs: From structural insights to in silico drug discovery

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