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Phosphodiesterases as therapeutic targets for respiratory diseases

Pharmacology & therapeutics (Oxford), 2019-05, Vol.197, p.225-242

2019

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Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

PLoS biology, 2009-08, Vol.7 (8), p.e1000172

2009

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Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

PloS one, 2009-04, Vol.4 (4), p.e5106-e5106

2009

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Signaling by internalized G-protein-coupled receptors

Trends in pharmacological sciences (Regular ed.), 2010-05, Vol.31 (5), p.221-228

2010

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cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels

Circulation (New York, N.Y.), 2017-12, Vol.136 (24), p.2337-2355

2017

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Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Nature communications, 2018-06, Vol.9 (1), p.2446-9, Article 2446

2018

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Cardiac cGMP Signaling in Health and Disease: Location, Location, Location

Journal of cardiovascular pharmacology, 2020-05, Vol.75 (5), p.399

2020

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Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women

PloS one, 2022-02, Vol.17 (2), p.e0263312-e0263312

2022

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Multifaceted remodelling of cAMP microdomains driven by different aetiologies of heart failure

The FEBS journal, 2021-12, Vol.288 (23), p.6603-6622

2021

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Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (17), p.5527-5532

2015

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cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging

International journal of molecular sciences, 2018-03, Vol.19 (3), p.801

2018

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Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes

PloS one, 2010-03, Vol.5 (3), p.e9689

2010

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Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism

European heart journal, 2023-07, Vol.44 (27), p.2483-2494

2023

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Biophysical techniques for detection of cAMP and cGMP in living cells

International Journal of Molecular Sciences, 2013-04, Vol.14 (4), p.8025-8046

2013

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Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure

Circulation (New York, N.Y.), 2018-07, Vol.138 (5), p.494-508

2018

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Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance

The Journal of neuroscience, 2016-05, Vol.36 (20), p.5636-5649

2016

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Cyclic nucleotide imaging and cardiovascular disease

Pharmacology & therapeutics (Oxford), 2017-07, Vol.175, p.107-115

2017

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Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation

Circulation research, 2020-09, Vol.127 (8), p.1036-1055

2020

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Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases

Frontiers in endocrinology (Lausanne), 2023-08, Vol.14, p.1239492-1239492

2023

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A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation

Frontiers in immunology, 2024, Vol.15, p.1365484-1365484

2024

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β₂-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

Science (American Association for the Advancement of Science), 2010-03, Vol.327 (5973), p.1653-1657

2010

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Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

Development (Cambridge), 2009-06, Vol.136 (11), p.1869-1878

2009

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FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

Nature protocols, 2011-04, Vol.6 (4), p.427-438

2011

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GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

The Journal of clinical investigation, 2015-12, Vol.125 (12), p.4714-4728

2015

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Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

Circulation research, 2016-09, Vol.119 (8), p.944-955

2016

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Phosphodiesterases as therapeutic targets for respiratory diseases

Persistent cAMP-signals triggered by internalized G-protein-coupled receptors

Sweet taste receptor expressed in pancreatic beta-cells activates the calcium and cyclic AMP signaling systems and stimulates insulin secretion

Signaling by internalized G-protein-coupled receptors

cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels

Distinct submembrane localisation compartmentalises cardiac NPR1 and NPR2 signalling to cGMP

Cardiac cGMP Signaling in Health and Disease: Location, Location, Location

Polycystic ovarian syndrome increases prevalence of concentric hypertrophy in normotensive obese women

Multifaceted remodelling of cAMP microdomains driven by different aetiologies of heart failure

Intercellular signaling via cyclic GMP diffusion through gap junctions restarts meiosis in mouse ovarian follicles

cGMP Signaling in the Cardiovascular System-The Role of Compartmentation and Its Live Cell Imaging

Bile acid-induced arrhythmia is mediated by muscarinic M2 receptors in neonatal rat cardiomyocytes

Phosphodiesterase 8 governs cAMP/PKA-dependent reduction of L-type calcium current in human atrial fibrillation: a novel arrhythmogenic mechanism

Biophysical techniques for detection of cAMP and cGMP in living cells

Endothelial C-Type Natriuretic Peptide Acts on Pericytes to Regulate Microcirculatory Flow and Blood Pressure

Cyclic Nucleotide Control of Microtubule Dynamics for Axon Guidance

Cyclic nucleotide imaging and cardiovascular disease

Atrial Myocyte NLRP3/CaMKII Nexus Forms a Substrate for Postoperative Atrial Fibrillation

Regulation of the renin-angiotensin-aldosterone system by cyclic nucleotides and phosphodiesterases

A mini-review: phosphodiesterases in charge to balance intracellular cAMP during T-cell activation

β₂-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

FRET measurements of intracellular cAMP concentrations and cAMP analog permeability in intact cells

GLP-1 stimulates insulin secretion by PKC-dependent TRPM4 and TRPM5 activation

Microdomain-Specific Modulation of L-Type Calcium Channels Leads to Triggered Ventricular Arrhythmia in Heart Failure

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