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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Scientific reports, 2019-11, Vol.9 (1), p.16890-15, Article 16890

2019

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Sidedness of carbamazepine accessibility to voltage-gated sodium channels

Molecular pharmacology, 2014-02, Vol.85 (2), p.381-387

2014

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1315-1327

2020

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Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin

Marine drugs, 2016-02, Vol.14 (2), p.36

2016

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The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

British journal of pharmacology, 2014-01, Vol.171 (2), p.427

2014

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Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

Annual review of pharmacology and toxicology, 2020-01, Vol.60 (1), p.133-154

2020

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Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs

European journal of pharmacology, 2015-10, Vol.764, p.395-403

2015

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Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)

Pflügers Archiv, 2014-02, Vol.466 (2), p.253-263

2014

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Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

BMC cardiovascular disorders, 2016-01, Vol.16 (1), p.1-1, Article 1

2016

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Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Journal of biomolecular screening, 2016-06, Vol.21 (5), p.480-489

2016

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Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Channels (Austin, Tex.), 2016-11, Vol.10 (6), p.478-497

2016

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Cannabidiol interactions with voltage-gated sodium channels

eLife, 2020-10, Vol.9

2020

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Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

American journal of respiratory and critical care medicine, 2016-09, Vol.194 (6), p.701-710

2016

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Role of Sodium and Calcium Dysregulation in Tachyarrhythmias in Sudden Cardiac Death

Circulation research, 2015-06, Vol.116 (12), p.1956-1970

2015

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Altered Na(+) currents in atrial fibrillation effects of ranolazine on arrhythmias and contractility in human atrial myocardium

Journal of the American College of Cardiology, 2010-05, Vol.55 (21), p.2330-2342

2010

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Targeting ion channels in cystic fibrosis

Journal of cystic fibrosis, 2015-09, Vol.14 (5), p.561-570

2015

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Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels

American journal of physiology: Gastrointestinal and liver physiology, 2022-02, Vol.322 (2), p.G201-G222

2022

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iCTX-Type: A Sequence-Based Predictor for Identifying the Types of Conotoxins in Targeting Ion Channels

BioMed research international, 2014-01, Vol.2014, p.286419-10

2014

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Activation of the Endogenous Renin-Angiotensin-Aldosterone System or Aldosterone Administration Increases Urinary Exosomal Sodium Channel Excretion

Journal of the American Society of Nephrology, 2016-02, Vol.27 (2), p.646-656

2016

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An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

Journal of pharmacological and toxicological methods, 2016-09, Vol.81 (C), p.251-262

2016

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Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells

Nature reviews. Nephrology, 2014-03, Vol.10 (3), p.146-157

2014

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Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

PloS one, 2016-11, Vol.11 (11), p.e0166143

2016

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Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

The Journal of general physiology, 2013-01, Vol.141 (1), p.61-72

2013

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Veratridine-sensitive Na+ channels regulate human sperm fertilization capacity

Life sciences (1973), 2018-03, Vol.196, p.48-55

2018

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Phenotypic spectrum and genetics of SCN2A‐related disorders, treatment options, and outcomes in epilepsy and beyond

Epilepsia (Copenhagen), 2019-12, Vol.60 (S3), p.S59-S67

2019

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High-throughput screening against protein:protein interaction interfaces reveals anti-cancer therapeutics as potent modulators of the voltage-gated Na + channel complex

Sidedness of carbamazepine accessibility to voltage-gated sodium channels

Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

Development of a Rapid Throughput Assay for Identification of hNav1.7 Antagonist Using Unique Efficacious Sodium Channel Agonist, Antillatoxin

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

Structure and Pharmacology of Voltage-Gated Sodium and Calcium Channels

Differential modulation of Nav1.7 and Nav1.8 channels by antidepressant drugs

Pharmacological and electrophysiological characterization of the human bile acid-sensitive ion channel (hBASIC)

Regulation of SCN3B/scn3b by Interleukin 2 (IL-2): IL-2 modulates SCN3B/scn3b transcript expression and increases sodium current in myocardial cells

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Dynamical characterization of inactivation path in voltage-gated Na+ ion channel by non-equilibrium response spectroscopy

Cannabidiol interactions with voltage-gated sodium channels

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

Role of Sodium and Calcium Dysregulation in Tachyarrhythmias in Sudden Cardiac Death

Altered Na(+) currents in atrial fibrillation effects of ranolazine on arrhythmias and contractility in human atrial myocardium

Targeting ion channels in cystic fibrosis

Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels

iCTX-Type: A Sequence-Based Predictor for Identifying the Types of Conotoxins in Targeting Ion Channels

Activation of the Endogenous Renin-Angiotensin-Aldosterone System or Aldosterone Administration Increases Urinary Exosomal Sodium Channel Excretion

An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

Blood pressure and amiloride-sensitive sodium channels in vascular and renal cells

Hyperthermia Influences the Effects of Sodium Channel Blocking Drugs in Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics

Veratridine-sensitive Na+ channels regulate human sperm fertilization capacity

Phenotypic spectrum and genetics of SCN2A‐related disorders, treatment options, and outcomes in epilepsy and beyond

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