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Comparison of amine additives most effective in the new methyltrioxorhenium-catalyzed epoxidation process

Tetrahedron letters, 1999-05, Vol.40 (21), p.3991-3994

1999

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Studies toward the Synthesis of Azadirachtin, Part 2: Construction of Fully Functionalized ABCD Ring Frameworks and Unusual Intramolecular Reactions Induced by Close-Proximity Effects

Angewandte Chemie (International ed.), 2005-05, Vol.44 (22), p.3447-3452

2005

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Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.1685-1694

2022

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Development of a sp2–sp3 Stille Cross-Coupling for Rapid Synthesis of HIV NNRTI Doravirine Analogues

Organic letters, 2017-06, Vol.19 (12), p.3071-3074

2017

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Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity

Bioorganic & medicinal chemistry letters, 2023-06, Vol.89, p.129303-129303, Article 129303

2023

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Simple and efficient routes for the preparation of isoxazolidinyl nucleosides containing cytosine and 5-methyl-cytosine as new potential anti-HIV drugs

Tetrahedron, 2001-10, Vol.57 (40), p.8551-8557

2001

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2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: multigram display of azide and cyanide components on a versatile scaffold

Molecules (Basel, Switzerland), 2006-03, Vol.11 (4), p.212-218

2006

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Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Journal of chemical information and modeling, 2020-09, Vol.60 (9), p.4144-4152

2020

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Development of a sp 2 -sp 3 Stille Cross-Coupling for Rapid Synthesis of HIV NNRTI Doravirine Analogues

Organic letters, 2017-06, Vol.19 (12), p.3071-3074

2017

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Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1

Science translational medicine, 2023-02, Vol.15 (684), p.eabn2038

2023

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Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models

Bioorganic & medicinal chemistry letters, 2020-05, Vol.30 (9), p.127066-127066, Article 127066

2020

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Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV‑1 Integrase Inhibitors with Antiretroviral Activity

ACS chemical biology, 2017-11, Vol.12 (11), p.2858-2865

2017

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The Selective Phosphodiesterase 9 (PDE9) Inhibitor PF-04447943 Attenuates a Scopolamine-Induced Deficit in a Novel Rodent Attention Task

Journal of neurogenetics, 2011-12, Vol.25 (4), p.120-126

2011

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Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Journal of biomolecular screening, 2016-06, Vol.21 (5), p.480-489

2016

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Development of thioquinazolinones, allosteric Chk1 kinase inhibitors

Bioorganic & medicinal chemistry letters, 2009-02, Vol.19 (4), p.1240-1244

2009

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Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Bioorganic & medicinal chemistry letters, 2014-06, Vol.24 (12), p.2737-2740

2014

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Studies toward the Synthesis of Azadirachtin, Part 1: Total Synthesis of a Fully Functionalized ABC Ring Framework and Coupling with a Norbornene Domain

Angewandte Chemie (International ed.), 2005-05, Vol.44 (22), p.3443-3447

2005

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Nucleophilic Substitution by Grignard Reagents on Sulfur Mustards

Journal of organic chemistry, 2004-10, Vol.69 (21), p.7336-7339

2004

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Studies toward the Synthesis of Azadirachtin, Part 2: Construction of Fully Functionalized ABCD Ring Frameworks and Unusual Intramolecular Reactions Induced by Close-Proximity Effects

Angewandte Chemie, 2005-05, Vol.117 (22), p.3513-3518

2005

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2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: A Privileged, Bivalent Scaffold for the Display of Nucleophilic Components

Journal of organic chemistry, 2001-06, Vol.66 (12), p.4386-4392

2001

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Improved Process for the Preparation of Nucleosidic Phosphoramidites Using a Safer and Cheaper Activator

Organic process research & development, 2000-05, Vol.4 (3), p.175-181

2000

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Studies toward the Synthesis of Azadirachtin, Part 1: Total Synthesis of a Fully Functionalized ABC Ring Framework and Coupling with a Norbornene Domain

Angewandte Chemie, 2005-05, Vol.117 (22), p.3509-3513

2005

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ChemInform Abstract: Synthesis of Modified 2′,3′-Dideoxynucleosides as Potential Antiviral Drugs

ChemInform, 1999-08, Vol.30 (34), p.no-no

1999

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Comparison of amine additives most effective in the new methyltrioxorhenium-catalyzed epoxidation process

Studies toward the Synthesis of Azadirachtin, Part 2: Construction of Fully Functionalized ABCD Ring Frameworks and Unusual Intramolecular Reactions Induced by Close-Proximity Effects

Dose Number as a Tool to Guide Lead Optimization for Orally Bioavailable Compounds in Drug Discovery

Development of a sp2–sp3 Stille Cross-Coupling for Rapid Synthesis of HIV NNRTI Doravirine Analogues

Discovery of arylsulfonamides as a novel class of allosteric integrase inhibitors with antiviral activity

Simple and efficient routes for the preparation of isoxazolidinyl nucleosides containing cytosine and 5-methyl-cytosine as new potential anti-HIV drugs

2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: multigram display of azide and cyanide components on a versatile scaffold

Augmenting Hit Identification by Virtual Screening Techniques in Small Molecule Drug Discovery

Development of a sp 2 -sp 3 Stille Cross-Coupling for Rapid Synthesis of HIV NNRTI Doravirine Analogues

Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1

Discovery of 4-arylquinoline-2-carboxamides, highly potent and selective class of mGluR2 negative allosteric modulators: From HTS to activity in animal models

A Phenotypic Screen Identifies Potent DPP9 Inhibitors Capable of Killing HIV‑1 Infected Cells

Discovery of a Distinct Chemical and Mechanistic Class of Allosteric HIV‑1 Integrase Inhibitors with Antiretroviral Activity

Discovery of MK-8768, a Potent and Selective mGluR2 Negative Allosteric Modulator

The Selective Phosphodiesterase 9 (PDE9) Inhibitor PF-04447943 Attenuates a Scopolamine-Induced Deficit in a Novel Rodent Attention Task

Kinetic Analysis of Membrane Potential Dye Response to NaV1.7 Channel Activation Identifies Antagonists with Pharmacological Selectivity against NaV1.5

Development of thioquinazolinones, allosteric Chk1 kinase inhibitors

Adenosine analogue inhibitors of S-adenosylhomocysteine hydrolase

Studies toward the Synthesis of Azadirachtin, Part 1: Total Synthesis of a Fully Functionalized ABC Ring Framework and Coupling with a Norbornene Domain

Nucleophilic Substitution by Grignard Reagents on Sulfur Mustards

Studies toward the Synthesis of Azadirachtin, Part 2: Construction of Fully Functionalized ABCD Ring Frameworks and Unusual Intramolecular Reactions Induced by Close-Proximity Effects

2,6-Dichloro-9-thiabicyclo[3.3.1]nonane: A Privileged, Bivalent Scaffold for the Display of Nucleophilic Components

Improved Process for the Preparation of Nucleosidic Phosphoramidites Using a Safer and Cheaper Activator

Studies toward the Synthesis of Azadirachtin, Part 1: Total Synthesis of a Fully Functionalized ABC Ring Framework and Coupling with a Norbornene Domain

ChemInform Abstract: Synthesis of Modified 2′,3′-Dideoxynucleosides as Potential Antiviral Drugs

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