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The action potential in mammalian central neurons

Nature reviews. Neuroscience, 2007-06, Vol.8 (6), p.451-465

Bean, Bruce P

2007

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Breaking barriers to novel analgesic drug development

Nature reviews. Drug discovery, 2017-08, Vol.16 (8), p.545-564

2017

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Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons

Neuron (Cambridge, Mass.), 2018-03, Vol.97 (6), p.1315-1326.e3

2018

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Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

Cell reports (Cambridge), 2014-04, Vol.7 (1), p.1-11

2014

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Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons

The Journal of neuroscience, 2014-04, Vol.34 (14), p.4991-5002

2014

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Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances

The Journal of neuroscience, 2010-05, Vol.30 (21), p.7401-7413

2010

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Cannabidiol inhibits Nav channels through two distinct binding sites

Nature communications, 2023-06, Vol.14 (1), p.3613-3613, Article 3613

2023

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Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation

The Journal of neuroscience, 2013-09, Vol.33 (38), p.15011-15021

2013

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Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation

Neuron (Cambridge, Mass.), 2015-07, Vol.87 (2), p.341-354

2015

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Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons

The Journal of neuroscience, 2015-12, Vol.35 (50), p.16404-16417

2015

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Sodium Entry during Action Potentials of Mammalian Neurons: Incomplete Inactivation and Reduced Metabolic Efficiency in Fast-Spiking Neurons

Neuron (Cambridge, Mass.), 2009-12, Vol.64 (6), p.898-909

2009

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Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

Nature, 2007-10, Vol.449 (7162), p.607-610

2007

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Developing nociceptor-selective treatments for acute and chronic pain

Science translational medicine, 2021-11, Vol.13 (619), p.eabj9837

2021

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Roles of Subthreshold Calcium Current and Sodium Current in Spontaneous Firing of Mouse Midbrain Dopamine Neurons

The Journal of neuroscience, 2007-01, Vol.27 (3), p.645-656

2007

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Action Potential Broadening in Capsaicin-Sensitive DRG Neurons from Frequency-Dependent Reduction of Kv3 Current

The Journal of neuroscience, 2017-10, Vol.37 (40), p.9705-9714

2017

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Inhibition of neuronal voltage-gated sodium channels by brilliant blue G

Molecular pharmacology, 2011-08, Vol.80 (2), p.247-257

2011

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Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker

British journal of pharmacology, 2021-10, Vol.178 (19), p.3905-3923

2021

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Roles of Tetrodotoxin (TTX)-Sensitive Na+ Current, TTX-Resistant Na+ Current, and Ca2+ Current in the Action Potentials of Nociceptive Sensory Neurons

The Journal of neuroscience, 2002-12, Vol.22 (23), p.10277-10290

2002

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Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms

Neuron (Cambridge, Mass.), 2012-09, Vol.75 (6), p.1081-1093

2012

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Cannabidiol activates neuronal Kv7 channels

eLife, 2022-02, Vol.11

2022

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Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

Journal of neurophysiology, 2013-04, Vol.109 (7), p.1704-1712

2013

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Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing

The Journal of neuroscience, 2013-01, Vol.33 (1), p.315-326

2013

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Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels

eLife, 2016-04, Vol.5

2016

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Subthreshold Sodium Current from Rapidly Inactivating Sodium Channels Drives Spontaneous Firing of Tuberomammillary Neurons

Neuron (Cambridge, Mass.), 2002-02, Vol.33 (4), p.587-600

2002

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Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

Anesthesiology (Philadelphia), 2009-07, Vol.111 (1), p.127-137

2009

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The action potential in mammalian central neurons

Breaking barriers to novel analgesic drug development

Differential Control of Axonal and Somatic Resting Potential by Voltage-Dependent Conductances in Cortical Layer 5 Pyramidal Neurons

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

Kv2 channel regulation of action potential repolarization and firing patterns in superior cervical ganglion neurons and hippocampal CA1 pyramidal neurons

Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances

Cannabidiol inhibits Nav channels through two distinct binding sites

Persistent sodium current drives conditional pacemaking in CA1 pyramidal neurons under muscarinic stimulation

Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation

Differential Regulation of Action Potential Shape and Burst-Frequency Firing by BK and Kv2 Channels in Substantia Nigra Dopaminergic Neurons

Sodium Entry during Action Potentials of Mammalian Neurons: Incomplete Inactivation and Reduced Metabolic Efficiency in Fast-Spiking Neurons

Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers

Developing nociceptor-selective treatments for acute and chronic pain

Roles of Subthreshold Calcium Current and Sodium Current in Spontaneous Firing of Mouse Midbrain Dopamine Neurons

Action Potential Broadening in Capsaicin-Sensitive DRG Neurons from Frequency-Dependent Reduction of Kv3 Current

Inhibition of neuronal voltage-gated sodium channels by brilliant blue G

Inhibition of inflammatory pain and cough by a novel charged sodium channel blocker

Roles of Tetrodotoxin (TTX)-Sensitive Na+ Current, TTX-Resistant Na+ Current, and Ca2+ Current in the Action Potentials of Nociceptive Sensory Neurons

Transient Sodium Current at Subthreshold Voltages: Activation by EPSP Waveforms

Cannabidiol activates neuronal Kv7 channels

Permeation and block of TRPV1 channels by the cationic lidocaine derivative QX-314

Phenotyping the function of TRPV1-expressing sensory neurons by targeted axonal silencing

Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels

Subthreshold Sodium Current from Rapidly Inactivating Sodium Channels Drives Spontaneous Firing of Tuberomammillary Neurons

Coapplication of Lidocaine and the Permanently Charged Sodium Channel Blocker QX-314 Produces a Long-lasting Nociceptive Blockade in Rodents

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