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Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets

The Journal of immunology (1950), 2018-10, Vol.201 (8), p.2215-2219

2018

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PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (16), p.1

2021

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Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity

Science (American Association for the Advancement of Science), 2021-01, Vol.371 (6527), p.405-410

2021

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

Journal of clinical oncology, 2019-03, Vol.37 (9), p.741-750

2019

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Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

Gastroenterology (New York, N.Y. 1943), 2019-05, Vol.156 (6), p.1788-1804.e13

2019

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PI3Kγ is a molecular switch that controls immune suppression

Nature (London), 2016-11, Vol.539 (7629), p.437-442

2016

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Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Science (American Association for the Advancement of Science), 2019-11, Vol.366 (6466), p.714-723

2019

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Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

The Journal of biological chemistry, 2015-07, Vol.290 (28), p.17495-17504

2015

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Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4 + T Cell Proliferation

American journal of respiratory cell and molecular biology, 2017-01, Vol.56 (1), p.74-82

2017

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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Clinical cancer research, 2012-08, Vol.18 (15), p.4104-4113

2012

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Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Blood, 2006-06, Vol.107 (11), p.4458-4465

2006

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Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis

Gastroenterology (New York, N.Y. 1943), 2017-06, Vol.152 (8), p.1985-1997.e12

2017

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Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation

Molecular biology of the cell, 2022-04, Vol.33 (4), p.ar31

2022

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Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (30), p.E4338-E4347

2016

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Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

Genes & development, 2014-12, Vol.28 (23), p.2621-2635

2014

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High-Mobility Group Box 1 (HMGB1) Promotes Angiogenesis and Tumor Migration by Regulating Hypoxia-Inducible Factor 1 (HIF-1α) Expression via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Signaling Pathway in Breast Cancer Cells

Medical science monitor, 2019-04, Vol.25, p.2352-2360

2019

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Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

The Journal of immunology (1950), 2020-07, Vol.205 (1), p.78-89

2020

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Resveratrol Modulates Interleukin-1β-induced Phosphatidylinositol 3-Kinase and Nuclear Factor κB Signaling Pathways in Human Tenocytes

The Journal of biological chemistry, 2012-11, Vol.287 (45), p.38050-38063

2012

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A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

Nature (London), 2015-04, Vol.520 (7549), p.683-687

2015

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G protein-coupled receptors (GPCRs) That Signal via Protein Kinase A (PKA) Cross-talk at Insulin Receptor Substrate 1 (IRS1) to Activate the phosphatidylinositol 3-kinase (PI3K)/AKT Pathway

The Journal of biological chemistry, 2016-12, Vol.291 (53), p.27160-27169

2016

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A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation

The Journal of immunology (1950), 2019-06, Vol.202 (12), p.3381-3393

2019

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Luminal B breast cancer: molecular characterization, clinical management, and future perspectives

Journal of clinical oncology, 2014-09, Vol.32 (25), p.2794-2803

2014

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Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

Proceedings of the National Academy of Sciences - PNAS, 2014-11, Vol.111 (47), p.16826-16829

2014

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class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

The Journal of cell biology, 2010-11, Vol.191 (4), p.827-843

2010

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Insulin Receptor Substrate 2-mediated Phosphatidylinositol 3-kinase Signaling Selectively Inhibits Glycogen Synthase Kinase 3β to Regulate Aerobic Glycolysis

The Journal of biological chemistry, 2014-06, Vol.289 (26), p.18603-18613

2014

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Cutting Edge: TGF-β and Phosphatidylinositol 3-Kinase Signals Modulate Distinct Metabolism of Regulatory T Cell Subsets

PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response

Glycolysis fuels phosphoinositide 3-kinase signaling to bolster T cell immunity

Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

Estrogen Activation of G-Protein–Coupled Estrogen Receptor 1 Regulates Phosphoinositide 3-Kinase and mTOR Signaling to Promote Liver Growth in Zebrafish and Proliferation of Human Hepatocytes

PI3Kγ is a molecular switch that controls immune suppression

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors

Signaling through the Phosphatidylinositol 3-Kinase (PI3K)/Mammalian Target of Rapamycin (mTOR) Axis Is Responsible for Aerobic Glycolysis mediated by Glucose Transporter in Epidermal Growth Factor Receptor (EGFR)-mutated Lung Adenocarcinoma

Programmed Death-1 Inhibition of Phosphatidylinositol 3-Kinase/AKT/Mechanistic Target of Rapamycin Signaling Impairs Sarcoidosis CD4 + T Cell Proliferation

Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Antigen receptor–mediated changes in glucose metabolism in B lymphocytes: role of phosphatidylinositol 3-kinase signaling in the glycolytic control of growth

Solute Carrier Family 39 Member 6 Gene Promotes Aggressiveness of Esophageal Carcinoma Cells by Increasing Intracellular Levels of Zinc, Activating Phosphatidylinositol 3-Kinase Signaling, and Up-regulating Genes That Regulate Metastasis

Endosomal cargo recycling mediated by Gpa1 and phosphatidylinositol 3-kinase is inhibited by glucose starvation

Phosphoinositide 3-kinase inhibitors induce DNA damage through nucleoside depletion

Pancreatic cell plasticity and cancer initiation induced by oncogenic Kras is completely dependent on wild-type PI 3-kinase p110α

High-Mobility Group Box 1 (HMGB1) Promotes Angiogenesis and Tumor Migration by Regulating Hypoxia-Inducible Factor 1 (HIF-1α) Expression via the Phosphatidylinositol 3-Kinase (PI3K)/AKT Signaling Pathway in Breast Cancer Cells

Loss of Phosphatidylinositol 3-Kinase Activity in Regulatory T Cells Leads to Neuronal Inflammation

Resveratrol Modulates Interleukin-1β-induced Phosphatidylinositol 3-Kinase and Nuclear Factor κB Signaling Pathways in Human Tenocytes

A molecular mechanism of artemisinin resistance in Plasmodium falciparum malaria

G protein-coupled receptors (GPCRs) That Signal via Protein Kinase A (PKA) Cross-talk at Insulin Receptor Substrate 1 (IRS1) to Activate the phosphatidylinositol 3-kinase (PI3K)/AKT Pathway

A Precision B Cell-Targeted Therapeutic Approach to Autoimmunity Caused by Phosphatidylinositol 3-Kinase Pathway Dysregulation

Luminal B breast cancer: molecular characterization, clinical management, and future perspectives

Oncogenic activity of the regulatory subunit p85β of phosphatidylinositol 3-kinase (PI3K)

class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy

Insulin Receptor Substrate 2-mediated Phosphatidylinositol 3-kinase Signaling Selectively Inhibits Glycogen Synthase Kinase 3β to Regulate Aerobic Glycolysis

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