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Adult Glioblastoma

Journal of clinical oncology, 2017-07, Vol.35 (21), p.2402-2409

2017

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Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials

Neurotherapeutics, 2017-04, Vol.14 (2), p.307-320

2017

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Glioblastoma: from molecular pathology to targeted treatment

Annual review of pathology, 2014-01, Vol.9 (1), p.1-25

2014

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mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

Cell metabolism, 2013-11, Vol.18 (5), p.726-739

2013

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Ivosidenib in Isocitrate Dehydrogenase 1 - Mutated Advanced Glioma

Journal of clinical oncology, 2020-10, Vol.38 (29), p.3398-3406

2020

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Design and Evaluation of an External Control Arm Using Prior Clinical Trials and Real-World Data

Clinical cancer research, 2019-08, Vol.25 (16), p.4993-5001

2019

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EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling

Molecular cell, 2015-10, Vol.60 (2), p.307-318

2015

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Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial

Clinical cancer research, 2021-08, Vol.27 (16), p.4491-4499

2021

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mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT

Molecular cell, 2017-07, Vol.67 (1), p.128-138.e7

2017

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Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

Neuro-oncology (Charlottesville, Va.), 2016-04, Vol.18 (4), p.557-564

2016

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Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

Cell metabolism, 2019-09, Vol.30 (3), p.525-538.e8

2019

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Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6166), p.72-76

2014

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Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

Journal of clinical oncology, 2010-04, Vol.28 (11), p.1963-1972

2010

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Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II–III diffuse gliomas

Journal of neuro-oncology, 2017-08, Vol.134 (1), p.177-188

2017

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The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings

Clinical biochemistry, 2014-03, Vol.47 (4-5), p.258-266

2014

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2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

Cell metabolism, 2015-09, Vol.22 (3), p.508-515

2015

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Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma

Cancer cell, 2016-04, Vol.29 (4), p.563-573

2016

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Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (30), p.9406-9411

2015

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Toward precision medicine in glioblastoma: the promise and the challenges

Neuro-oncology (Charlottesville, Va.), 2015-08, Vol.17 (8), p.1051-1063

2015

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Platform trials arrive on time for glioblastoma

Neuro-oncology (Charlottesville, Va.), 2018-05, Vol.20 (6), p.723-725

2018

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Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

Nature genetics, 2010-01, Vol.42 (1), p.77-82

2010

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Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

Nature communications, 2021-06, Vol.12 (1), p.4031-4031, Article 4031

2021

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Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

Journal of neuro-oncology, 2012-03, Vol.107 (1), p.197-205

2012

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Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

The New England journal of medicine, 2005-11, Vol.353 (19), p.2012-2024

2005

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Phase II Study of Aflibercept in Recurrent Malignant Glioma: A North American Brain Tumor Consortium Study

Journal of clinical oncology, 2011-07, Vol.29 (19), p.2689-2695

2011

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Adult Glioblastoma

Modified Criteria for Radiographic Response Assessment in Glioblastoma Clinical Trials

Glioblastoma: from molecular pathology to targeted treatment

mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

Ivosidenib in Isocitrate Dehydrogenase 1 - Mutated Advanced Glioma

Design and Evaluation of an External Control Arm Using Prior Clinical Trials and Real-World Data

EGFR Mutation Promotes Glioblastoma through Epigenome and Transcription Factor Network Remodeling

Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial

mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT

Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study

Oncogene Amplification in Growth Factor Signaling Pathways Renders Cancers Dependent on Membrane Lipid Remodeling

Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA

Updated Response Assessment Criteria for High-Grade Gliomas: Response Assessment in Neuro-Oncology Working Group

Perfusion and diffusion MRI signatures in histologic and genetic subtypes of WHO grade II–III diffuse gliomas

The procurement, storage, and quality assurance of frozen blood and tissue biospecimens in pathology, biorepository, and biobank settings

2-Hydroxyglutarate Inhibits ATP Synthase and mTOR Signaling

Single-Cell Phosphoproteomics Resolves Adaptive Signaling Dynamics and Informs Targeted Combination Therapy in Glioblastoma

Glucose-dependent acetylation of Rictor promotes targeted cancer therapy resistance

Toward precision medicine in glioblastoma: the promise and the challenges

Platform trials arrive on time for glioblastoma

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

Resolution of tissue signatures of therapy response in patients with recurrent GBM treated with neoadjuvant anti-PD1

Non-invasive detection of 2-hydroxyglutarate and other metabolites in IDH1 mutant glioma patients using magnetic resonance spectroscopy

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

Phase II Study of Aflibercept in Recurrent Malignant Glioma: A North American Brain Tumor Consortium Study

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