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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Cell, 2012-08, Vol.150 (4), p.685-696

2012

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Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

Journal of clinical oncology, 2009-10, Vol.27 (28), p.4733-4740

2009

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Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation

Nature communications, 2021-01, Vol.12 (1), p.139-139, Article 139

2021

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Role of AKT signaling in DNA repair and clinical response to cancer therapy

Neuro-oncology (Charlottesville, Va.), 2014-10, Vol.16 (10), p.1313-1323

2014

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Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma

Acta neuropathologica, 2015-10, Vol.130 (4), p.587-597

2015

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Molecular Mechanisms of Treatment Resistance in Glioblastoma

International journal of molecular sciences, 2020-12, Vol.22 (1), p.351

2020

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Current clinical development of PI3K pathway inhibitors in glioblastoma

Neuro-oncology (Charlottesville, Va.), 2012-07, Vol.14 (7), p.819-829

2012

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Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas

Neuro-oncology (Charlottesville, Va.), 2008-04, Vol.10 (2), p.162-170

2008

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Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

Journal of clinical oncology, 2018-05, Vol.36 (14), p.1419-1427

2018

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Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

Journal of neuro-oncology, 2012-05, Vol.107 (3), p.487-501

2012

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EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma

Clinical cancer research, 2020-03, Vol.26 (6), p.1395-1407

2020

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Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma

Journal of neuro-oncology, 2009-09, Vol.94 (2), p.229-234

2009

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Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas

Journal of neuro-oncology, 2017-03, Vol.132 (1), p.181-188

2017

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Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers

Oncotarget, 2014-09, Vol.5 (18), p.8202-8210

2014

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Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients

Cancer chemotherapy and pharmacology, 2012-06, Vol.69 (6), p.1507-1518

2012

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Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation

Journal of neuro-oncology, 2008-06, Vol.88 (2), p.121-133

2008

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Antitumor Activity of NVP-BKM120―A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells

Clinical cancer research, 2012-01, Vol.18 (1), p.184-195

2012

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Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma

Cancer research (Chicago, Ill.), 2019-10, Vol.79 (19), p.5088-5101

2019

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Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE

Clinical cancer research, 2018-02, Vol.24 (4), p.737-743

2018

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The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas

Journal of Immunotherapy and Precision Oncology, 2020-11, Vol.3 (4), p.157-164

2020

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Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

Clinical cancer research, 2015-10, Vol.21 (20), p.4630-4641

2015

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Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.3421-3426

2015

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Moving toward molecular classification of diffuse gliomas in adults

Neurology, 2012-10, Vol.79 (18), p.1917

2012

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A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma

Neuro-oncology (Charlottesville, Va.), 2020-10, Vol.22 (10), p.1505-1515

2020

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PKM2 Phosphorylates Histone H3 and Promotes Gene Transcription and Tumorigenesis

Bevacizumab Alone and in Combination With Irinotecan in Recurrent Glioblastoma

Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation

Role of AKT signaling in DNA repair and clinical response to cancer therapy

Phase 1 lead‐in to a phase 2 factorial study of temozolomide plus memantine, mefloquine, and metformin as postradiation adjuvant therapy for newly diagnosed glioblastoma

Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma

Molecular Mechanisms of Treatment Resistance in Glioblastoma

Current clinical development of PI3K pathway inhibitors in glioblastoma

Progression-free survival: an important end point in evaluating therapy for recurrent high-grade gliomas

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma

Induction of cell-cycle arrest and apoptosis in glioblastoma stem-like cells by WP1193, a novel small molecule inhibitor of the JAK2/STAT3 pathway

EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma

Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma

Phase I trial of aflibercept (VEGF trap) with radiation therapy and concomitant and adjuvant temozolomide in patients with high-grade gliomas

Tissue-specific isoform switch and DNA hypomethylation of the pyruvate kinase PKM gene in human cancers

Phase I study of AEE788, a novel multitarget inhibitor of ErbB- and VEGF-receptor-family tyrosine kinases, in recurrent glioblastoma patients

Knockdown of GluR1 expression by RNA interference inhibits glioma proliferation

Antitumor Activity of NVP-BKM120―A Selective Pan Class I PI3 Kinase Inhibitor Showed Differential Forms of Cell Death Based on p53 Status of Glioma Cells

Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma

Adaptive Global Innovative Learning Environment for Glioblastoma: GBM AGILE

The Promise of Poly(ADP-Ribose) Polymerase (PARP) Inhibitors in Gliomas

Macitentan, a Dual Endothelin Receptor Antagonist, in Combination with Temozolomide Leads to Glioblastoma Regression and Long-term Survival in Mice

Genomically amplified Akt3 activates DNA repair pathway and promotes glioma progression

Moving toward molecular classification of diffuse gliomas in adults

A Bayesian adaptive randomized phase II multicenter trial of bevacizumab with or without vorinostat in adults with recurrent glioblastoma

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