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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

Clinical cancer research, 2012-08, Vol.18 (15), p.4104-4113

2012

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CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

Cancer research (Chicago, Ill.), 2010-05, Vol.70 (9), p.3647-3656

2010

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CUDC-305, a Novel Synthetic HSP90 Inhibitor with Unique Pharmacologic Properties for Cancer Therapy

Clinical cancer research, 2009-06, Vol.15 (12), p.4046-4057

2009

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Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non–small cell lung cancer

Molecular cancer therapeutics, 2009-12, Vol.8 (12), p.3296-3306

2009

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Feasibility study on expanded indication for endoscopic submucosal dissection of intramucosal poorly differentiated early gastric cancer

World journal of gastroenterology : WJG, 2016-08, Vol.22 (29), p.6736-6741

2016

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Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate

Chinese journal of chemistry, 1994-03, Vol.12 (2), p.174-178

1994

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Phosphatidylinositol Phospholipase C Is Activated Allosterically by the Aminoglycoside G418

The Journal of biological chemistry, 1996-06, Vol.271 (26), p.15468-15477

1996

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Abstract C70: Antitumor activity of CUDC-907, a single small molecule inhibitor that targets both PI3K and HDAC, in hematologic cancer models

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.C70-C70

2011

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Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.3249-3249

2011

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Abstract 2619: Potential advantages of CUDC-101, a multi-targeted HDAC, EGFR and HER2 inhibitor, on preventing drug resistance and tumor metastasis

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2619-2619

2011

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Regioselective etherification of l,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol

Chinese journal of chemistry, 1996-05, Vol.14 (3), p.271-278

1996

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Abstract 4469: Antitumor activity of a single small molecule agent targeting Pi3K/mTor and HDAC

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4469-4469

2010

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Nonspecific Effect of Stress on Brain Gray Matter Volume in Drug-naive Female Patients with First Depressive Episode

Chinese medical journal, 2016-02, Vol.129 (3), p.279-283

2016

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Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2-deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonate and its analogs inhibit glycosylphosphatidylinositol phospholipase C

The Journal of biological chemistry, 1996-06, Vol.271 (26), p.15468

1996

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Inhibition of GPI Phospholipase C fromTrypanosoma bruceiby Fluoro-Inositol Dodecylphosphonates

Biochemical and biophysical research communications, 1998-03, Vol.244 (3), p.873-876

1998

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Synthesis of 2-deoxy-2-fluorinated inositol-1-0-dodecylphosphonates as inhibitors of glycosyl phosphatidylinositol phospholipase C

Tetrahedron letters, 1995-10, Vol.36 (41), p.7403-7406

1995

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Inhibition of GPI phospholipase C from Trypanosoma brucei by fluoro-inositol dodecylphosphonates

Biochemical and biophysical research communications, 1998-03, Vol.244 (3), p.873-876

1998

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Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2- Deoxy-2-fluoro-scyllo-inositol-1-O-dodecyl phosphonate and its analogs inhibit glycosyl-phosphatidylinositol phospholipase C

The Journal of biological chemistry, 1996-01, Vol.271 (26), p.15468-15477

1996

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Cyclocarya paliurus tea leaves enhances pancreatic β cell preservation through inhibition of apoptosis

Scientific reports, 2017-08, Vol.7 (1), p.9155-13, Article 9155

2017

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Identification of α-glucosidase inhibitors from cyclocarya paliurus tea leaves using UF-UPLC-Q/TOF-MS/MS and molecular docking

Food & function, 2019-04, Vol.10 (4), p.1893-1902

2019

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Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages

Chinese medicine, 2020-05, Vol.15 (1), p.43-43, Article 43

2020

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Engineering Saccharomyces cerevisiae for geranylgeraniol overproduction by combinatorial design

Scientific reports, 2017-11, Vol.7 (1), p.14991-11, Article 14991

2017

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Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study

Frontiers in pharmacology, 2018-08, Vol.9, p.973-973

2018

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P2Y1R Ligation Suppresses Th17 Cell Differentiation and Alleviates Colonic Inflammation in an AMPK-Dependent Manner

Frontiers in immunology, 2022-02, Vol.13, p.820524-820524

2022

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Berberine Suppresses Colonic Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activity

Frontiers in pharmacology, 2020-11, Vol.11, p.576496-576496

2020

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Cancer Network Disruption by a Single Molecule Inhibitor Targeting Both Histone Deacetylase Activity and Phosphatidylinositol 3-Kinase Signaling

CUDC-101, a Multitargeted Inhibitor of Histone Deacetylase, Epidermal Growth Factor Receptor, and Human Epidermal Growth Factor Receptor 2, Exerts Potent Anticancer Activity

CUDC-305, a Novel Synthetic HSP90 Inhibitor with Unique Pharmacologic Properties for Cancer Therapy

Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non–small cell lung cancer

Feasibility study on expanded indication for endoscopic submucosal dissection of intramucosal poorly differentiated early gastric cancer

Synthesis of 1,4,6-tri-O-benzyl myo-inositol-A key intermediate to myo-inositol-1,2,5-O-trisphosphate

Phosphatidylinositol Phospholipase C Is Activated Allosterically by the Aminoglycoside G418

Abstract C70: Antitumor activity of CUDC-907, a single small molecule inhibitor that targets both PI3K and HDAC, in hematologic cancer models

Abstract 3249: Design and synthesis of imidazopyridine derivatives as novel HSP90 inhibitors for the treatment of cancer

Abstract 2619: Potential advantages of CUDC-101, a multi-targeted HDAC, EGFR and HER2 inhibitor, on preventing drug resistance and tumor metastasis

Regioselective etherification of l,2-O-isopropylidene-4,6-di-O-benzyl myo-inositol

Abstract 4469: Antitumor activity of a single small molecule agent targeting Pi3K/mTor and HDAC

Nonspecific Effect of Stress on Brain Gray Matter Volume in Drug-naive Female Patients with First Depressive Episode

Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2-deoxy-2-fluoro-scyllo-inositol-1-O-dodecylphosphonate and its analogs inhibit glycosylphosphatidylinositol phospholipase C

Inhibition of GPI Phospholipase C fromTrypanosoma bruceiby Fluoro-Inositol Dodecylphosphonates

Synthesis of 2-deoxy-2-fluorinated inositol-1-0-dodecylphosphonates as inhibitors of glycosyl phosphatidylinositol phospholipase C

Inhibition of GPI phospholipase C from Trypanosoma brucei by fluoro-inositol dodecylphosphonates

Phosphatidylinositol phospholipase C is activated allosterically by the aminoglycoside G418. 2- Deoxy-2-fluoro-scyllo-inositol-1-O-dodecyl phosphonate and its analogs inhibit glycosyl-phosphatidylinositol phospholipase C

Cyclocarya paliurus tea leaves enhances pancreatic β cell preservation through inhibition of apoptosis

Identification of α-glucosidase inhibitors from cyclocarya paliurus tea leaves using UF-UPLC-Q/TOF-MS/MS and molecular docking

Anti-inflammatory properties of uvaol on DSS-induced colitis and LPS-stimulated macrophages

Engineering Saccharomyces cerevisiae for geranylgeraniol overproduction by combinatorial design

Cyclocarya paliurus Leaves Tea Improves Dyslipidemia in Diabetic Mice: A Lipidomics-Based Network Pharmacology Study

P2Y1R Ligation Suppresses Th17 Cell Differentiation and Alleviates Colonic Inflammation in an AMPK-Dependent Manner

Berberine Suppresses Colonic Inflammation in Dextran Sulfate Sodium-Induced Murine Colitis Through Inhibition of Cytosolic Phospholipase A2 Activity

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