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Amide bond formation: beyond the myth of coupling reagents

Chemical Society reviews, 2009, Vol.38 (2), p.606-631

2009

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New Modalities for Challenging Targets in Drug Discovery

Angewandte Chemie International Edition, 2017-08, Vol.56 (35), p.10294-10323

International ed. in English, 2017

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Therapeutic Potential of Foldamers: From Chemical Biology Tools To Drug Candidates?

Journal of medicinal chemistry, 2016-11, Vol.59 (21), p.9599-9621

2016

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Directing evolution: the next revolution in drug discovery?

Nature reviews. Drug discovery, 2017-10, Vol.16 (10), p.681-698

2017

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Late‐Stage Functionalization of Histidine in Unprotected Peptides

Angewandte Chemie International Edition, 2019-12, Vol.58 (52), p.19096-19102

International ed. in English, 2019

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Amide bond formation: beyond the myth of coupling reagents

Chemical Society reviews, 2009-02, Vol.38 (2), p.606-631

2009

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Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell

Journal of the American Chemical Society, 2021-03, Vol.143 (9), p.3416-3429

2021

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A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Nature communications, 2020-10, Vol.11 (1), p.5425-5425, Article 5425

2020

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Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Journal of medicinal chemistry, 2011-03, Vol.54 (5), p.1233-1243

2011

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Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung

Angewandte Chemie, 2017-08, Vol.129 (35), p.10428-10459

2017

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Efficient, mild, parallel and purification-free synthesis of aryl ethers via the Mitsunobu reaction

Tetrahedron letters, 2008-06, Vol.49 (26), p.4182-4185

2008

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New Modalities, Technologies, and Partnerships in Probe and Lead Generation: Enabling a Mode-of-Action Centric Paradigm

Journal of medicinal chemistry, 2018-10, Vol.61 (20), p.9004-9029

2018

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Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (16), p.7926-7931

2019

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Emerging modes-of-action in drug discovery

MedChemComm, 2019-09, Vol.1 (9), p.155-1568

2019

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Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

Journal of the American Chemical Society, 2020-03, Vol.142 (10), p.4904-4915

2020

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PS-IIDQ: a supported coupling reagent for efficient and general amide bond formation

Tetrahedron, 2007-09, Vol.63 (36), p.8855-8871

2007

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Targeted delivery for regenerative medicines: an untapped opportunity for drug conjugates

Drug discovery today, 2017-06, Vol.22 (6), p.841-847

2017

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Discovery of 4-((2 S ,4 S )-4-Ethoxy-1-((5-methoxy-7-methyl-1 H -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

Journal of medicinal chemistry, 2020-06, Vol.63 (11), p.5697-5722

2020

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase

Chemical science (Cambridge), 2018-07, Vol.9 (27), p.5957-5966

2018

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligaseElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01186a

2018-07

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Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01186a

Chemical science (Cambridge), 2018-06, Vol.9 (27), p.5957-5966

2018

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Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung

Angewandte Chemie, 2017-08, Vol.129 (35), p.10428-10459

2017

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Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors

Bioorganic & medicinal chemistry letters, 2018-03, Vol.28 (5), p.906-909

2018

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Analysis of Chemical Shift Changes Reveals the Binding Modes of Isoindolinone Inhibitors of the MDM2-p53 Interaction

Journal of the American Chemical Society, 2008-11, Vol.130 (47), p.16038-16044

2008

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PS-SNAP, a practical polymer-supported nitrosation reagent in organic synthesis

Tetrahedron letters, 2010-04, Vol.51 (17), p.2277-2280

2010

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Amide bond formation: beyond the myth of coupling reagents

New Modalities for Challenging Targets in Drug Discovery

Therapeutic Potential of Foldamers: From Chemical Biology Tools To Drug Candidates?

Directing evolution: the next revolution in drug discovery?

Late‐Stage Functionalization of Histidine in Unprotected Peptides

Amide bond formation: beyond the myth of coupling reagents

Glucagon Like Peptide 1 Receptor Agonists for Targeted Delivery of Antisense Oligonucleotides to Pancreatic Beta Cell

A protein tertiary structure mimetic modulator of the Hippo signalling pathway

Isoindolinone Inhibitors of the Murine Double Minute 2 (MDM2)-p53 Protein−Protein Interaction: Structure−Activity Studies Leading to Improved Potency

Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung

Efficient, mild, parallel and purification-free synthesis of aryl ethers via the Mitsunobu reaction

New Modalities, Technologies, and Partnerships in Probe and Lead Generation: Enabling a Mode-of-Action Centric Paradigm

Small-molecule factor B inhibitor for the treatment of complement-mediated diseases

Emerging modes-of-action in drug discovery

Macrocyclic Modalities Combining Peptide Epitopes and Natural Product Fragments

PS-IIDQ: a supported coupling reagent for efficient and general amide bond formation

Targeted delivery for regenerative medicines: an untapped opportunity for drug conjugates

Discovery of 4-((2 S ,4 S )-4-Ethoxy-1-((5-methoxy-7-methyl-1 H -indol-4-yl)methyl)piperidin-2-yl)benzoic Acid (LNP023), a Factor B Inhibitor Specifically Designed To Be Applicable to Treating a Diverse Array of Complement Mediated Diseases

Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase

Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligaseElectronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01186a

Inhibition of low-density lipoprotein receptor degradation with a cyclic peptide that disrupts the homodimerization of IDOL E3 ubiquitin ligase† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c8sc01186a

Neue Modalitäten für schwierige Zielstrukturen in der Wirkstoffentwicklung

Structure-based design and synthesis of macrocyclic human rhinovirus 3C protease inhibitors

Analysis of Chemical Shift Changes Reveals the Binding Modes of Isoindolinone Inhibitors of the MDM2-p53 Interaction

PS-SNAP, a practical polymer-supported nitrosation reagent in organic synthesis

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