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Rh(III)/Cu(II)-cocatalyzed synthesis of 1H-indazoles through C-H amidation and N-N bond formation

Journal of the American Chemical Society, 2013-06, Vol.135 (24), p.8802-8805

2013

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Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives

Molecules (Basel, Switzerland), 2018-10, Vol.23 (11), p.2783

2018

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Copper-Catalyzed Aerobic C(sp2)–H Functionalization for C–N Bond Formation: Synthesis of Pyrazoles and Indazoles

Journal of organic chemistry, 2013-04, Vol.78 (8), p.3636-3646

2013

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Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

Journal of medicinal chemistry, 2017-02, Vol.60 (4), p.1262-1271

2017

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Switching on prodrugs using radiotherapy

Nature chemistry, 2021-08, Vol.13 (8), p.805

2021

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Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

Journal of medicinal chemistry, 2017-04, Vol.60 (7), p.2983-2992

2017

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Regiodivergent Cu-Promoted, AcOH-Switchable Distal Versus Proximal Direct Cyanation of 1-Aryl-1 H -indazoles and 2-Aryl-2 H -indazoles via Aerobic Oxidative C-H Bond Activation

Journal of organic chemistry, 2022-12, Vol.87 (24), p.16188-16203

2022

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Synthesis of indazole motifs and their medicinal importance: An overview

European journal of medicinal chemistry, 2015-01, Vol.90, p.707-731

2015

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Unparalleled Ease of Access to a Library of Biheteroaryl Fluorophores via Oxidative Cross-Coupling Reactions: Discovery of Photostable NIR Probe for Mitochondria

Journal of the American Chemical Society, 2016-04, Vol.138 (14), p.4730-4738

2016

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Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis

Journal of the American Chemical Society, 2020-06, Vol.142 (23), p.10550-10556

2020

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Rhodium(III)-Catalyzed Indazole Synthesis by C–H Bond Functionalization and Cyclative Capture

Journal of the American Chemical Society, 2013-05, Vol.135 (19), p.7122-7125

2013

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Photochemical Preparation of 1,2-Dihydro-3 H-indazol-3-ones in Aqueous Solvent at Room Temperature

Journal of organic chemistry, 2018-12, Vol.83 (24), p.15493-15498

2018

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Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades

Journal of the American Chemical Society, 2015-01, Vol.137 (1), p.490-498

2015

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Copper-Catalyzed C(sp2)–H Amidation with Azides as Amino Sources

Organic letters, 2014-09, Vol.16 (18), p.4702-4705

2014

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USP7 small-molecule inhibitors interfere with ubiquitin binding

Nature (London), 2017-10, Vol.550 (7677), p.534-538

2017

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A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Nature chemical biology, 2012-11, Vol.8 (11), p.890

2012

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Ocular Drug Delivery Nanowafer with Enhanced Therapeutic Efficacy

ACS nano, 2015-02, Vol.9 (2), p.1749-1758

2015

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Direct Arylations of 2H-Indazoles On Water

Organic letters, 2010-01, Vol.12 (2), p.224-226

2010

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Discovery of 2 H -Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy

Journal of medicinal chemistry, 2023-05, Vol.66 (9), p.6218-6238

2023

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Predictive Model for Site-Selective Aryl and Heteroaryl C–H Functionalization via Organic Photoredox Catalysis

Journal of the American Chemical Society, 2017-08, Vol.139 (32), p.11288-11299

2017

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Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease

Journal of medicinal chemistry, 2015-09, Vol.58 (18), p.7381-7399

2015

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Access to 3‑Acyl-(2H)‑indazoles via Rh(III)-Catalyzed C–H Addition and Cyclization of Azobenzenes with α‑Keto Aldehydes

Organic letters, 2016-01, Vol.18 (2), p.232-235

2016

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Niraparib: A Poly(ADP-ribose) Polymerase (PARP) Inhibitor for the Treatment of Tumors with Defective Homologous Recombination

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3302-3314

2015

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Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

Nature (London), 2015-03, Vol.519 (7541), p.102-105

2015

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Rh(III)/Cu(II)-cocatalyzed synthesis of 1H-indazoles through C-H amidation and N-N bond formation

Recent Advances in Indazole-Containing Derivatives: Synthesis and Biological Perspectives

Copper-Catalyzed Aerobic C(sp2)–H Functionalization for C–N Bond Formation: Synthesis of Pyrazoles and Indazoles

Structural Basis for Potency and Promiscuity in Poly(ADP-ribose) Polymerase (PARP) and Tankyrase Inhibitors

Switching on prodrugs using radiotherapy

Discovery of a 3‑(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity

Regiodivergent Cu-Promoted, AcOH-Switchable Distal Versus Proximal Direct Cyanation of 1-Aryl-1 H -indazoles and 2-Aryl-2 H -indazoles via Aerobic Oxidative C-H Bond Activation

Synthesis of indazole motifs and their medicinal importance: An overview

Unparalleled Ease of Access to a Library of Biheteroaryl Fluorophores via Oxidative Cross-Coupling Reactions: Discovery of Photostable NIR Probe for Mitochondria

Highly Enantioselective Synthesis of Indazoles with a C3-Quaternary Chiral Center Using CuH Catalysis

Rhodium(III)-Catalyzed Indazole Synthesis by C–H Bond Functionalization and Cyclative Capture

Photochemical Preparation of 1,2-Dihydro-3 H-indazol-3-ones in Aqueous Solvent at Room Temperature

Discovery of Entrectinib: A New 3‑Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c‑ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Cobalt(III)-Catalyzed Synthesis of Indazoles and Furans by C–H Bond Functionalization/Addition/Cyclization Cascades

Copper-Catalyzed C(sp2)–H Amidation with Azides as Amino Sources

USP7 small-molecule inhibitors interfere with ubiquitin binding

A selective inhibitor of EZH2 blocks H3K27 methylation and kills mutant lymphoma cells

Ocular Drug Delivery Nanowafer with Enhanced Therapeutic Efficacy

Direct Arylations of 2H-Indazoles On Water

Discovery of 2 H -Indazole-3-carboxamide Derivatives as Novel Potent Prostanoid EP4 Receptor Antagonists for Colorectal Cancer Immunotherapy

Predictive Model for Site-Selective Aryl and Heteroaryl C–H Functionalization via Organic Photoredox Catalysis

Optimization of Novel Indazoles as Highly Potent and Selective Inhibitors of Phosphoinositide 3‑Kinase δ for the Treatment of Respiratory Disease

Access to 3‑Acyl-(2H)‑indazoles via Rh(III)-Catalyzed C–H Addition and Cyclization of Azobenzenes with α‑Keto Aldehydes

Niraparib: A Poly(ADP-ribose) Polymerase (PARP) Inhibitor for the Treatment of Tumors with Defective Homologous Recombination

Axitinib effectively inhibits BCR-ABL1(T315I) with a distinct binding conformation

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