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Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Nature chemical biology, 2013-09, Vol.9 (9), p.548

2013

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Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury

Molecular cancer therapeutics, 2018-03, Vol.17 (3), p.603-613

2018

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Establishment and genomic characterization of the new chordoma cell line Chor-IN-1

Scientific reports, 2017-08, Vol.7 (1), p.9226-14, Article 9226

2017

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Molecular Dynamics Simulations of p97 Including Covalent, Allosteric and ATP-competitive Inhibitors

Acta chimica Slovenica, 2019-06, Vol.66 (2), p.395-401

2019

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Faces of Geometry: II Edition

1st ed. 2021., 2021

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Faces of Geometry. from Agnesi to Mirzakhani

1st ed. 2020., 2019

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Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

Molecular cancer therapeutics, 2016-04, Vol.15 (4), p.628-639

2016

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A fast and straightforward procedure for vault nanoparticle purification and the characterization of its endocytic uptake

Biochimica et biophysica acta. General subjects, 2018-10, Vol.1862 (10), p.2254-2260

2018

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Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

Biochemistry (Easton), 2010-08, Vol.49 (32), p.6813-6825

2010

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Molecular Dynamics Simulations of p97 Including Covalent, Allosteric and ATP-competitive Inhibitors

Acta chimica Slovenica, 2019-06, Vol.66 (2), p.395-401

2019

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Discovery of 2‑(Cyclohexylmethylamino)pyrimidines as a New Class of Reversible Valosine Containing Protein Inhibitors

Journal of medicinal chemistry, 2014-12, Vol.57 (24), p.10443-10454

2014

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Abstract 74: Establishment and characterization of the new sacral chordoma cell line Chor-IN-1

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.74-74

2015

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Development of biochemical assays for the identification of eIF4E-specific inhibitors

Journal of biomolecular screening, 2012-06, Vol.17 (5), p.581-592

2012

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Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.2940-2940

2012

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Luca Pacioli: A Friend of Leonardo da Vinci De Divina Proportione in Capital Letters

ICGG 2018 - Proceedings of the 18th International Conference on Geometry and Graphics, p.2205-2208

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HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3

Nature genetics, 1998-09, Vol.20 (1), p.74-77

1998

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Abstract A243: Characterization of NMS-E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK-dependent lymphoma and non-small cell lung cancer models

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A244-A244

2009

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Short direct repeats at the breakpoints of a novel large deletion in the CFTR gene suggest a likely slipped mispairing mechanism

Human genetics, 1996-07, Vol.98 (1), p.102-108

1996

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THE SIZE AND SHAPE OF DANTE'S MOUNT PURGATORY

Journal of astronomical history and heritage, 2015-07, Vol.18 (2), p.123-134

2015

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Transposition of Biomimetical Principles into Generative Design: Example of the Species Campanula patula L

Faces of Geometry, 2021, Vol.172

2021

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Geometrical Solution for the Trisection Problem

Faces of Geometry, 2021, Vol.172, p.193-208

2021

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Discovery of Entrectinib: A New 3‑Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c‑ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Covalent and allosteric inhibitors of the ATPase VCP/p97 induce cancer cell death

Afatinib Is a New Therapeutic Approach in Chordoma with a Unique Ability to Target EGFR and Brachyury

Establishment and genomic characterization of the new chordoma cell line Chor-IN-1

Molecular Dynamics Simulations of p97 Including Covalent, Allosteric and ATP-competitive Inhibitors

Faces of Geometry: II Edition

Faces of Geometry. from Agnesi to Mirzakhani

Entrectinib, a Pan-TRK, ROS1, and ALK Inhibitor with Activity in Multiple Molecularly Defined Cancer Indications

A fast and straightforward procedure for vault nanoparticle purification and the characterization of its endocytic uptake

Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

Alkylsulfanyl-1,2,4-triazoles, a New Class of Allosteric Valosine Containing Protein Inhibitors. Synthesis and Structure–Activity Relationships

Correction to Discovery of Entrectinib: A New 3‑Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c‑ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Molecular Dynamics Simulations of p97 Including Covalent, Allosteric and ATP-competitive Inhibitors

Discovery of 2‑(Cyclohexylmethylamino)pyrimidines as a New Class of Reversible Valosine Containing Protein Inhibitors

Abstract 74: Establishment and characterization of the new sacral chordoma cell line Chor-IN-1

Development of biochemical assays for the identification of eIF4E-specific inhibitors

Abstract 2940: Identification of potent VCP/p97/CDC48 inhibitors with distinct biochemical mechanisms including a reversible, allosteric inhibitor that activates the unfolded protein response, induce autophagy and cancer cell death

Luca Pacioli: A Friend of Leonardo da Vinci De Divina Proportione in Capital Letters

HIRA, a mammalian homologue of Saccharomyces cerevisiae transcriptional co-repressors, interacts with Pax3

Abstract A243: Characterization of NMS-E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK-dependent lymphoma and non-small cell lung cancer models

Short direct repeats at the breakpoints of a novel large deletion in the CFTR gene suggest a likely slipped mispairing mechanism

THE SIZE AND SHAPE OF DANTE'S MOUNT PURGATORY

Transposition of Biomimetical Principles into Generative Design: Example of the Species Campanula patula L

Geometrical Solution for the Trisection Problem

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