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Diastereoselective synthesis of anti and syn .alpha.,.beta.-dihydroxy thioesters by titanium enolate aldol condensation

Journal of organic chemistry, 1992-11, Vol.57 (23), p.6339-6342

1992

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Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

Biochemistry (Easton), 2010-08, Vol.49 (32), p.6813-6825

2010

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Abstract 1324: NMS-P088, a novel FLT3, KIT and CSF1R inhibitor, is a promising clinical candidate for AML and CMML treatment

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1324-1324

2019

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A Phase I/II Study of NMS-03592088, a FLT3, KIT and CSF1R Inhibitor, in Patients with Relapsed or Refractory AML or CMML

Blood, 2019-11, Vol.134 (Supplement_1), p.3855-3855

2019

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Abstract 4785: NMS-E668, a highly potent orally available RET inhibitor with selectivity towards VEGFR2 and demonstrated antitumor efficacy in multiple RET-driven cancer models

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.4785-4785

2018

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Abstract 805: NMS-P088, a FLT3-KIT-CSF-1R inhibitor with activity on FLT3 F691L as a novel agent in AML

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.805-805

2018

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Multistep synthesis of a new tricyclic azaindole-based scaffold

Tetrahedron letters, 2009-09, Vol.50 (36), p.5156-5158

2009

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Abstract 798: NMS-P088, a dual FLT3-KIT inhibitor active also on gatekeeper mutations and devoid of QTc prolongation

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.798-798

2015

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Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor

Bioorganic & medicinal chemistry, 1998-07, Vol.6 (7), p.947-958

1998

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Abstract B230: NMS-P948, a potent dual FLT3/KIT inhibitor, also active on secondary resistance mutations

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.B230-B230

2011

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Abstract A243: Characterization of NMS-E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK-dependent lymphoma and non-small cell lung cancer models

Molecular cancer therapeutics, 2009-12, Vol.8 (12_Supplement), p.A244-A244

2009

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Facile Synthesis of 7-Amino-1,2,3,4-tetrahydro-β-carboline

ChemInform, 2004-02, Vol.35 (8), p.no-no

2004

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Facile Synthesis of 7-Amino-1,2,3,4-tetrahydro-β-carboline

Synthetic communications, 2003-11, Vol.33 (21), p.3707-3716

2003

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Research on anti-HIV-1 agents. Investigation on the CD4-Suradista binding mode through docking experiments

Journal of computer-aided molecular design, 2000-05, Vol.14 (4), p.355-368

2000

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Novel sulfonated and phosphonated analogs of distamycin which inhibit the replication of HIV

Antiviral Research, 1995-08, Vol.27 (4), p.335-354

1995

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Discovery of Entrectinib: A New 3‑Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c‑ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

The TPM3-NTRK1 rearrangement is a recurring event in colorectal carcinoma and is associated with tumor sensitivity to TRKA kinase inhibition

Diastereoselective synthesis of anti and syn .alpha.,.beta.-dihydroxy thioesters by titanium enolate aldol condensation

Crystal Structures of Anaplastic Lymphoma Kinase in Complex with ATP Competitive Inhibitors

Abstract 1324: NMS-P088, a novel FLT3, KIT and CSF1R inhibitor, is a promising clinical candidate for AML and CMML treatment

A Phase I/II Study of NMS-03592088, a FLT3, KIT and CSF1R Inhibitor, in Patients with Relapsed or Refractory AML or CMML

Abstract 4785: NMS-E668, a highly potent orally available RET inhibitor with selectivity towards VEGFR2 and demonstrated antitumor efficacy in multiple RET-driven cancer models

Abstract 805: NMS-P088, a FLT3-KIT-CSF-1R inhibitor with activity on FLT3 F691L as a novel agent in AML

Correction to Discovery of Entrectinib: A New 3‑Aminoindazole as a Potent Anaplastic Lymphoma Kinase (ALK), c‑ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Multistep synthesis of a new tricyclic azaindole-based scaffold

Abstract 798: NMS-P088, a dual FLT3-KIT inhibitor active also on gatekeeper mutations and devoid of QTc prolongation

Synthesis and binding mode of heterocyclic analogues of suramin inhibiting the human basic fibroblast growth factor

Abstract B230: NMS-P948, a potent dual FLT3/KIT inhibitor, also active on secondary resistance mutations

Abstract A243: Characterization of NMS-E628, a small molecule inhibitor of anaplastic lymphoma kinase with antitumor efficacy in ALK-dependent lymphoma and non-small cell lung cancer models

Facile Synthesis of 7-Amino-1,2,3,4-tetrahydro-β-carboline

Facile Synthesis of 7-Amino-1,2,3,4-tetrahydro-β-carboline

Research on anti-HIV-1 agents. Investigation on the CD4-Suradista binding mode through docking experiments

Novel sulfonated and phosphonated analogs of distamycin which inhibit the replication of HIV

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