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4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

European journal of medicinal chemistry, 2020-12, Vol.208, p.112720-112720, Article 112720

2020

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Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

European journal of medicinal chemistry, 2021-03, Vol.213, p.113161, Article 113161

2021

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Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation

European journal of medicinal chemistry, 2018-08, Vol.156, p.800-814

2018

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Modern trends in diuretics development

European journal of medicinal chemistry, 2020-12, Vol.208, p.112855-112855, Article 112855

2020

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128214-128214, Article 128214

2021

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Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Bioorganic & medicinal chemistry letters, 2018-09, Vol.28 (17), p.2979-2984

2018

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Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

European journal of medicinal chemistry, 2019-03, Vol.165, p.93-106

2019

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3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Bioorganic & medicinal chemistry, 2019-04, Vol.27 (7), p.1292-1307

2019

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Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Bioorganic & medicinal chemistry letters, 2020-07, Vol.30 (13), p.127197-127197, Article 127197

2020

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Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Bioorganic & medicinal chemistry, 2020-01, Vol.28 (1), p.115213, Article 115213

2020

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Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening

European journal of medicinal chemistry, 2019-02, Vol.163, p.649-659

2019

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Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors

European journal of medicinal chemistry, 2018-09, Vol.157, p.1361-1375

2018

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Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands

Bioorganic & medicinal chemistry letters, 2015-05, Vol.25 (9), p.1880-1883

2015

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Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

European journal of medicinal chemistry, 2019-04, Vol.167, p.105-123

2019

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Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors

European journal of medicinal chemistry, 2019-02, Vol.163, p.281-294

2019

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Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Bioorganic & medicinal chemistry, 2015-11, Vol.23 (21), p.6844-6854

2015

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Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Bioorganic & medicinal chemistry letters, 2020-06, Vol.30 (11), p.127143-127143, Article 127143

2020

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Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Bioorganic & medicinal chemistry letters, 2023-06, Vol.90, p.129331-129331, Article 129331

2023

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Antimicrobial peptides: Structure, mechanism, and modification

European journal of medicinal chemistry, 2023-07, Vol.255, p.115377-115377, Article 115377

2023

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Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Bioorganic & medicinal chemistry letters, 2018-11, Vol.28 (21), p.3446-3453

2018

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Design, synthesis and biological evaluation of chalcones as reversers of P-glycoprotein-mediated multidrug resistance

European journal of medicinal chemistry, 2019-10, Vol.180, p.350-366

2019

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Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Bioorganic & medicinal chemistry letters, 2019-01, Vol.29 (2), p.329-333

2019

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Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment

European journal of medicinal chemistry, 2021-08, Vol.220, p.113437-113437, Article 113437

2021

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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

European journal of medicinal chemistry, 2021-12, Vol.226, p.113873-113873, Article 113873

2021

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N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

European journal of medicinal chemistry, 2023-05, Vol.251, p.115227-115227, Article 115227

2023

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4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-β-lactamase inhibitors

Design, synthesis, and bioassay of 4-thiazolinone derivatives as influenza neuraminidase inhibitors

Synthesis and cytotoxic studies of novel 5-phenylisatin derivatives and their anti-migration and anti-angiogenic evaluation

Modern trends in diuretics development

SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Pyrazolo[3,4-d]pyrimidine derivatives containing a Schiff base moiety as potential antiviral agents

Searching for new agents active against Candida albicans biofilm: A series of indole derivatives, design, synthesis and biological evaluation

3,5-Dialkoxypyridine analogues of bedaquiline are potent antituberculosis agents with minimal inhibition of the hERG channel

Discovery of ethyl ketone-based HDACs 1, 2, and 3 selective inhibitors for HIV latency reactivation

Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology

Discovery of new potent hits against intracellular Trypanosoma cruzi by QSAR-based virtual screening

Structure-based drug design: Synthesis and biological evaluation of quinazolin-4-amine derivatives as selective Aurora A kinase inhibitors

Synthesis and biological evaluation of novel HIV-1 protease inhibitors using tertiary amine as P2-ligands

Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

Rational design of 5-((1H-imidazol-1-yl)methyl)quinolin-8-ol derivatives as novel bromodomain-containing protein 4 inhibitors

Structure activity relationships of benzyl C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists

Design, synthesis and anti-influenza A virus activity of novel 2,4-disubstituted quinazoline derivatives

Evaluating the druggability of TrmD, a potential antibacterial target, through design and microbiological profiling of a series of potent TrmD inhibitors

Antimicrobial peptides: Structure, mechanism, and modification

Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors

Design, synthesis and biological evaluation of chalcones as reversers of P-glycoprotein-mediated multidrug resistance

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Design, synthesis and biological evaluation of novel FXIa inhibitors with 2-phenyl-1H-imidazole-5-carboxamide moiety as P1 fragment

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

N-sulfonyl peptide-hybrids as a new class of dengue virus protease inhibitors

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