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A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases

Nature communications, 2017-09, Vol.8 (1), p.538-11, Article 538

2017

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Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins

Biochemical journal, 2014-12, Vol.464 (2), p.271-279

2014

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The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters

Trends in pharmacological sciences (Regular ed.), 2018-07, Vol.39 (7), p.635-647

2018

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Taxifolin as a Metallo-β-Lactamase Inhibitor in Combination with Augmentin against Verona Imipenemase 2 Expressing Pseudomonas aeruginosa

Microorganisms (Basel), 2023-10, Vol.11 (11), p.2653

2023

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Characterizing bourbon whiskey via the combination of LC-MS and GC–MS based molecular fingerprinting

Food chemistry, 2023-10, Vol.423, p.136311-136311, Article 136311

2023

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Multiple and Optimal Screening Subset: a method selecting global characteristic congeners for robust foodomics analysis

Briefings in bioinformatics, 2024-03, Vol.25 (2)

2024

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Metallo-β-lactamases: Novel Weaponry for Antibiotic Resistance in Bacteria

Accounts of chemical research, 2006-10, Vol.39 (10), p.721-728

2006

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Characterization of Zn(II)-responsive ribosomal proteins YkgM and L31 in E. coli

Journal of inorganic biochemistry, 2012-06, Vol.111, p.164-172

2012

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Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase‑1

Journal of medicinal chemistry, 2017-09, Vol.60 (17), p.7267-7283

2017

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Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity

The Journal of biological chemistry, 2018-08, Vol.293 (32), p.12606-12618

2018

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MBLinhibitors.com, a Website Resource Offering Information and Expertise for the Continued Development of Metallo-β-Lactamase Inhibitors

Biomolecules (Basel, Switzerland), 2020-03, Vol.10 (3), p.459

2020

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Structural Studies on a Mitochondrial Glyoxalase II

The Journal of biological chemistry, 2005-12, Vol.280 (49), p.40668-40675

2005

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Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase‑1 in Bacteria Using a Reversible Fluorescent Probe

Journal of the American Chemical Society, 2021-06, Vol.143 (22), p.8314-8323

2021

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Transcriptional Response of Escherichia coli to TPEN

Journal of Bacteriology, 2006-09, Vol.188 (18), p.6709-6713

2006

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Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM‑1

Journal of the American Chemical Society, 2014-05, Vol.136 (20), p.7273-7285

2014

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Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

Biochemistry (Easton), 2012-05, Vol.51 (18), p.3839-3847

2012

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1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

European journal of medicinal chemistry, 2021-12, Vol.226, p.113873-113873, Article 113873

2021

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The directed evolution of NDM-1

Antimicrobial agents and chemotherapy, 2023-11, Vol.67 (11), p.e0071423

2023

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Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2

Biochemical journal, 2009-01, Vol.417 (1), p.323-330

2009

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Fragment‐based screening and hit‐based substructure search: Rapid discovery of 8‐hydroxyquinoline‐7‐carboxylic acid as a low‐cytotoxic, nanomolar metallo β‐lactamase inhibitor

Chemical biology & drug design, 2021-10, Vol.98 (4), p.481-492

2021

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Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

Antimicrobial agents and chemotherapy, 2021-03, Vol.65 (4)

2021

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Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1

Journal of inorganic biochemistry, 2020-09, Vol.210, p.111123-111123, Article 111123

2020

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Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo‐β‐Lactamases

ChemMedChem, 2019-07, Vol.14 (13), p.1271-1282

2019

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A general reaction mechanism for carbapenem hydrolysis by mononuclear and binuclear metallo-β-lactamases

Targeting metallo-carbapenemases via modulation of electronic properties of cephalosporins

A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions

The Continuing Challenge of Metallo-β-Lactamase Inhibition: Mechanism Matters

Taxifolin as a Metallo-β-Lactamase Inhibitor in Combination with Augmentin against Verona Imipenemase 2 Expressing Pseudomonas aeruginosa

Characterizing bourbon whiskey via the combination of LC-MS and GC–MS based molecular fingerprinting

Multiple and Optimal Screening Subset: a method selecting global characteristic congeners for robust foodomics analysis

Metallo-β-lactamases: Novel Weaponry for Antibiotic Resistance in Bacteria

Characterization of Zn(II)-responsive ribosomal proteins YkgM and L31 in E. coli

Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase‑1

Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity

MBLinhibitors.com, a Website Resource Offering Information and Expertise for the Continued Development of Metallo-β-Lactamase Inhibitors

Structural Studies on a Mitochondrial Glyoxalase II

Visualizing the Dynamic Metalation State of New Delhi Metallo-β-lactamase‑1 in Bacteria Using a Reversible Fluorescent Probe

Transcriptional Response of Escherichia coli to TPEN

Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates

Spectroscopic and Mechanistic Studies of Heterodimetallic Forms of Metallo-β-lactamase NDM‑1

Mechanistic and Spectroscopic Studies of Metallo-β-lactamase NDM-1

1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity

The directed evolution of NDM-1

Arabidopsis thaliana GLX2-1 contains a dinuclear metal binding site, but is not a glyoxalase 2

Fragment‐based screening and hit‐based substructure search: Rapid discovery of 8‐hydroxyquinoline‐7‐carboxylic acid as a low‐cytotoxic, nanomolar metallo β‐lactamase inhibitor

Carbapenem Use Is Driving the Evolution of Imipenemase 1 Variants

Probing the mechanisms of inhibition for various inhibitors of metallo-β-lactamases VIM-2 and NDM-1

Investigation of Dipicolinic Acid Isosteres for the Inhibition of Metallo‐β‐Lactamases

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