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structural overview of the PDI family of proteins

The FEBS journal, 2010-10, Vol.277 (19), p.3924-3936

2010

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Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR

Nature communications, 2022-06, Vol.13 (1), p.3586-3586, Article 3586

2022

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ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

Science (American Association for the Advancement of Science), 2008-07, Vol.321 (5888), p.569-572

2008

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Protein quality control in the ER: The recognition of misfolded proteins

Seminars in cell & developmental biology, 2010-07, Vol.21 (5), p.500-511

2010

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Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX‐770 (ivacaftor)

British journal of pharmacology, 2016-02, Vol.173 (3), p.459-470

2016

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (9), p.E1152-E1161

2016

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Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells

Cellular physiology and biochemistry, 2021-12, Vol.55 (6), p.784-804

2021

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Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

Scientific reports, 2021-12, Vol.11 (1), p.23256-23256, Article 23256

2021

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An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases

Molecular & cellular proteomics, 2012-09, Vol.11 (9), p.710-723

2012

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The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway

Scientific reports, 2022-03, Vol.12 (1), p.4595-4595, Article 4595

2022

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The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia

American journal of physiology. Lung cellular and molecular physiology, 2016-01, Vol.310 (1), p.L59-L70

2016

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Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain

The Journal of biological chemistry, 2010-11, Vol.285 (46), p.35551-35557

2010

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Solution structure of the bb' domains of human protein disulfide isomerase

The FEBS journal, 2009-03, Vol.276 (5), p.1440-1449

2009

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Variable Responses to CFTR Correctors in vitro : Estimating the Design Effect in Precision Medicine

Frontiers in pharmacology, 2018-12, Vol.9, p.1490-1490

2018

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The Structure of Calnexin, an ER Chaperone Involved in Quality Control of Protein Folding

Molecular cell, 2001-09, Vol.8 (3), p.633-644

2001

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Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect

Molecular pharmacology, 2008-02, Vol.73 (2), p.478-489

2008

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Intracellular eukaryotic parasites have a distinct unfolded protein response

PloS one, 2011-04, Vol.6 (4), p.e19118-e19118

2011

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Crystal Structure of the bb′ Domains of the Protein Disulfide Isomerase ERp57

Structure (London), 2006-08, Vol.14 (8), p.1331-1339

2006

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Organization of the Sec61 Translocon, Studied by High Resolution Native Electrophoresis

Journal of proteome research, 2010-04, Vol.9 (4), p.1763-1771

2010

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Cold adaptation in budding yeast

Molecular biology of the cell, 2004-12, Vol.15 (12), p.5492-5502

2004

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Localization of the Lectin, ERp57 Binding, and Polypeptide Binding Sites of Calnexin and Calreticulin

The Journal of biological chemistry, 2002-08, Vol.277 (33), p.29686-29697

2002

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The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation

Nature structural & molecular biology, 2004-02, Vol.11 (2), p.128-134

2004

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Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking

ACS omega, 2020-10, Vol.5 (40), p.25593-25604

2020

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Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

Cells (Basel, Switzerland), 2022-01, Vol.11 (1), p.136

2022

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structural overview of the PDI family of proteins

Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR

ERdj5 Is Required as a Disulfide Reductase for Degradation of Misfolded Proteins in the ER

Protein quality control in the ER: The recognition of misfolded proteins

Low free drug concentration prevents inhibition of F508del CFTR functional expression by the potentiator VX‐770 (ivacaftor)

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Phosphodiesterase 8A Regulates CFTR Activity in Airway Epithelial Cells

Nonspecific binding of common anti-CFTR antibodies in ciliated cells of human airway epithelium

An Interaction Map of Endoplasmic Reticulum Chaperones and Foldases

The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway

The dual phosphodiesterase 3 and 4 inhibitor RPL554 stimulates CFTR and ciliary beating in primary cultures of bronchial epithelia

Structural Basis of Cyclophilin B Binding by the Calnexin/Calreticulin P-domain

Solution structure of the bb' domains of human protein disulfide isomerase

Variable Responses to CFTR Correctors in vitro : Estimating the Design Effect in Precision Medicine

The Structure of Calnexin, an ER Chaperone Involved in Quality Control of Protein Folding

Structural Analog of Sildenafil Identified as a Novel Corrector of the F508del-CFTR Trafficking Defect

Intracellular eukaryotic parasites have a distinct unfolded protein response

Crystal Structure of the bb′ Domains of the Protein Disulfide Isomerase ERp57

Organization of the Sec61 Translocon, Studied by High Resolution Native Electrophoresis

Cold adaptation in budding yeast

Localization of the Lectin, ERp57 Binding, and Polypeptide Binding Sites of Calnexin and Calreticulin

The ER protein folding sensor UDP-glucose glycoprotein-glucosyltransferase modifies substrates distant to local changes in glycoprotein conformation

Combination of Selective PARP3 and PARP16 Inhibitory Analogues of Latonduine A Corrects F508del-CFTR Trafficking

Rescue of Mutant CFTR Trafficking Defect by the Investigational Compound MCG1516A

Unravelling druggable signalling networks that control F508del-CFTR proteostasis

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