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Supramolecular chemical biology; bioactive synthetic self-assemblies

Organic & biomolecular chemistry, 2013, Vol.11 (2), p.219-232

2013

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Modulators of Protein–Protein Interactions

Chemical reviews, 2014-05, Vol.114 (9), p.4695-4748

2014

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Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

Nature reviews. Endocrinology, 2020-07, Vol.16 (7), p.363-377

2020

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Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions

Nature communications, 2020-08, Vol.11 (1), p.1-9, Article 3954

2020

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Modulators of 14-3‑3 Protein–Protein Interactions

Journal of medicinal chemistry, 2018-05, Vol.61 (9), p.3755-3778

2018

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Hydrophobicity Directed Chiral Self‐Assembly and Aggregation‐Induced Emission: Diacetylene‐Cored Pseudopeptide Chiral Dopants

Angewandte Chemie (International ed.), 2022-10, Vol.61 (42), p.e202209806-n/a

International ed. in English, 2022

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Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

Advanced synthesis & catalysis, 2015-07, Vol.357 (10), p.2180-2186

2015

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Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs

Journal of the American Chemical Society, 2020-05, Vol.142 (20), p.9106-9111

2020

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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3

Angewandte Chemie (International ed.), 2017-07, Vol.56 (31), p.8998-9002

International ed. in English, 2017

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377-OR: Stabilizing 14-3-3 and ChREBP Cytoplasmic Interaction to Rescue ß-Cells from Glucolipotoxicity

Diabetes (New York, N.Y.), 2023-06, Vol.72 (Supplement_1), p.1

2023

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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface

Journal of the American Chemical Society, 2017-11, Vol.139 (45), p.16256-16263

2017

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Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR

Nature communications, 2022-06, Vol.13 (1), p.3586-3586, Article 3586

2022

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Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis

ChemSusChem, 2016-07, Vol.9 (14), p.1781-1785

2016

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Stabilization and Inhibition of Protein–Protein Interactions: The 14-3‑3 Case Study

ACS chemical biology, 2013-01, Vol.8 (1), p.27-35

2013

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Stabilization of protein-protein interactions in drug discovery

Expert opinion on drug discovery, 2017-09, Vol.12 (9), p.925-940

2017

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Small-molecule inhibition of APT1 affects Ras localization and signaling

Nature chemical biology, 2010-06, Vol.6 (6), p.449

2010

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (9), p.E1152-E1161

2016

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Evaluation of Fluorophores to Label SNAP-Tag Fused Proteins for Multicolor Single-Molecule Tracking Microscopy in Live Cells

Biophysical journal, 2014-08, Vol.107 (4), p.803-814

2014

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Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains

Journal of the American Chemical Society, 2009-02, Vol.131 (4), p.1557-1564

2009

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Supramolecular Polymer as a Self-Assembling Polyvalent Scaffold

Angewandte Chemie (International ed.), 2009-04, Vol.48 (16), p.2921-2924

2009

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Membrane binding of lipidated Ras peptides and proteins — The structural point of view

Biochimica et biophysica acta, 2009-01, Vol.1788 (1), p.273-288

2009

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DNA‐Mediated Protein Shuttling between Coacervate‐Based Artificial Cells

Angewandte Chemie (International ed.), 2022-04, Vol.61 (17), p.e202115041-n/a

International ed. in English, 2022

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Small‐molecule stabilization of the p53 – 14‐3‐3 protein‐protein interaction

FEBS letters, 2017-08, Vol.591 (16), p.2449-2457

2017

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Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits

PloS one, 2015-11, Vol.10 (11), p.e0143162-e0143162

2015

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Synthesis and Crystal Structure of a Phosphorylated Estrogen Receptor Ligand Binding Domain

Chembiochem : a European journal of chemical biology, 2010-11, Vol.11 (16), p.2251-2254

2010

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Supramolecular chemical biology; bioactive synthetic self-assemblies

Modulators of Protein–Protein Interactions

Nuclear receptor crosstalk - defining the mechanisms for therapeutic innovation

Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions

Modulators of 14-3‑3 Protein–Protein Interactions

Hydrophobicity Directed Chiral Self‐Assembly and Aggregation‐Induced Emission: Diacetylene‐Cored Pseudopeptide Chiral Dopants

Metal-Free Photocatalytic Aerobic Oxidation of Thiols to Disulfides in Batch and Continuous-Flow

Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs

A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3

377-OR: Stabilizing 14-3-3 and ChREBP Cytoplasmic Interaction to Rescue ß-Cells from Glucolipotoxicity

The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface

Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR

Batch and Flow Synthesis of Disulfides by Visible-Light-Induced TiO2 Photocatalysis

Stabilization and Inhibition of Protein–Protein Interactions: The 14-3‑3 Case Study

Stabilization of protein-protein interactions in drug discovery

Small-molecule inhibition of APT1 affects Ras localization and signaling

Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR

Evaluation of Fluorophores to Label SNAP-Tag Fused Proteins for Multicolor Single-Molecule Tracking Microscopy in Live Cells

Influence of the Lipidation Motif on the Partitioning and Association of N-Ras in Model Membrane Subdomains

Supramolecular Polymer as a Self-Assembling Polyvalent Scaffold

Membrane binding of lipidated Ras peptides and proteins — The structural point of view

DNA‐Mediated Protein Shuttling between Coacervate‐Based Artificial Cells

Small‐molecule stabilization of the p53 – 14‐3‐3 protein‐protein interaction

Single Particle Tracking Reveals that EGFR Signaling Activity Is Amplified in Clathrin-Coated Pits

Synthesis and Crystal Structure of a Phosphorylated Estrogen Receptor Ligand Binding Domain

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