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High-resolution crystal structure of the human CB1 cannabinoid receptor

Nature (London), 2016-12, Vol.540 (7634), p.602-606

2016

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Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

Nature (London), 2015-03, Vol.519 (7542), p.247-250

2015

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Crystal structure of the human sterol transporter ABCG5/ABCG8

Nature (London), 2016-05, Vol.533 (7604), p.561-564

2016

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The structure and function of G-protein-coupled receptors

Nature, 2009-05, Vol.459 (7245), p.356-363

2009

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Structure and dynamics of the M3 muscarinic acetylcholine receptor

Nature (London), 2012-02, Vol.482 (7386), p.552-556

2012

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Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes

Cell, 2021-02, Vol.184 (4), p.943-956.e18

2021

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Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Nature (London), 2011-01, Vol.469 (7329), p.175-180

2011

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Structure and function of an irreversible agonist-β2 adrenoceptor complex

Nature (London), 2011-01, Vol.469 (7329), p.236-240

2011

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Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

Journal of neuroscience research, 2010-05, Vol.88 (7), p.1569-1576

2010

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Structure-based development of a subtype-selective orexin 1 receptor antagonist

Proceedings of the National Academy of Sciences - PNAS, 2020-07, Vol.117 (30), p.18059-18067

2020

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High-Resolution Crystal Structure of an Engineered Human β₂-Adrenergic G Protein-Coupled Receptor

Science (American Association for the Advancement of Science), 2007-11, Vol.318 (5854), p.1258-1265

2007

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On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies

Journal of biomolecular NMR, 2018-08, Vol.71 (4), p.203-211

2018

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Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

Nature structural & molecular biology, 2016-04, Vol.23 (4), p.293-299

2016

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Crystal structure of the human β2 adrenergic G-protein-coupled receptor

Nature (London), 2007-11, Vol.450 (7168), p.383-387

2007

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Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

Nature (London), 2010-01, Vol.463 (7277), p.108-112

2010

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Molecular mechanism of the wake-promoting agent TAK-925

Nature communications, 2022-05, Vol.13 (1), p.2902-12, Article 2902

2022

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The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits

PloS one, 2017-09, Vol.12 (9), p.e0184049-e0184049

2017

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Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA

Structure (London), 2018-01, Vol.26 (1), p.7-19.e5

2018

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Ligand modulation of sidechain dynamics in a wild-type human GPCR

eLife, 2017-10, Vol.6

2017

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Reply to: The G protein preference of orexin receptors is currently an unresolved issue

Nature communications, 2023-06, Vol.14 (1), p.3163-3163, Article 3163

2023

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Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo

mBio, 2024-05, Vol.15 (6), p.e0076824

2024

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Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK‐925 and ARN‐776 in narcoleptic orexin/tTA; TetO‐DTA mice

Journal of sleep research, 2023-08, Vol.32 (4), p.e13839-n/a

2023

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Erythropoietin Administration Protects Retinal Neurons from Acute Ischemia-Reperfusion Injury

Proceedings of the National Academy of Sciences - PNAS, 2002-08, Vol.99 (16), p.10659-10664

2002

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Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris

Journal of biomolecular NMR, 2015-07, Vol.62 (3), p.239-245

2015

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Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance

PloS one, 2013-03, Vol.8 (3), p.e57503-e57503

2013

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High-resolution crystal structure of the human CB1 cannabinoid receptor

Crystal structure of the human OX2 orexin receptor bound to the insomnia drug suvorexant

Crystal structure of the human sterol transporter ABCG5/ABCG8

The structure and function of G-protein-coupled receptors

Structure and dynamics of the M3 muscarinic acetylcholine receptor

Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Structure and function of an irreversible agonist-β2 adrenoceptor complex

Necroptosis, a novel form of caspase-independent cell death, contributes to neuronal damage in a retinal ischemia-reperfusion injury model

Structure-based development of a subtype-selective orexin 1 receptor antagonist

High-Resolution Crystal Structure of an Engineered Human β₂-Adrenergic G Protein-Coupled Receptor

On the use of Pichia pastoris for isotopic labeling of human GPCRs for NMR studies

Structure and ligand-binding mechanism of the human OX1 and OX2 orexin receptors

Crystal structure of the human β2 adrenergic G-protein-coupled receptor

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

Molecular mechanism of the wake-promoting agent TAK-925

The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits

Crystal Structures of Human Orexin 2 Receptor Bound to the Subtype-Selective Antagonist EMPA

Ligand modulation of sidechain dynamics in a wild-type human GPCR

Reply to: The G protein preference of orexin receptors is currently an unresolved issue

Development of a mutant aerosolized ACE2 that neutralizes SARS-CoV-2 in vivo

Evaluation of the efficacy of the hypocretin/orexin receptor agonists TAK‐925 and ARN‐776 in narcoleptic orexin/tTA; TetO‐DTA mice

Erythropoietin Administration Protects Retinal Neurons from Acute Ischemia-Reperfusion Injury

Methyl labeling and TROSY NMR spectroscopy of proteins expressed in the eukaryote Pichia pastoris

Long-term post-stroke changes include myelin loss, specific deficits in sensory and motor behaviors and complex cognitive impairment detected using active place avoidance

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