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Foldamer-templated catalysis of macrocycle formation

Science (American Association for the Advancement of Science), 2019-12, Vol.366 (6472), p.1528-1531

2019

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Ketones from Nickel‐Catalyzed Decarboxylative, Non‐Symmetric Cross‐Electrophile Coupling of Carboxylic Acid Esters

Angewandte Chemie (International ed.), 2019-08, Vol.58 (35), p.12081-12085

International ed. in English, 2019

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Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold

Journal of the American Chemical Society, 2022-02, Vol.144 (5), p.2225-2232

2022

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Modulation of hydrophobic interactions by proximally immobilized ions

Nature (London), 2015-01, Vol.517 (7534), p.347-350

2015

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Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation

Journal of the American Chemical Society, 2018-10, Vol.140 (39), p.12476-12483

2018

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Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets

Science (American Association for the Advancement of Science), 2021-03, Vol.371 (6536), p.1379-1382

2021

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Nylon‑3 Polymers Active against Drug-Resistant Candida albicans Biofilms

Journal of the American Chemical Society, 2015-02, Vol.137 (6), p.2183-2186

2015

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Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum

Organic letters, 2021-07, Vol.23 (13), p.5277-5281

2021

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

Nature (London), 2011-07, Vol.477 (7366), p.549-555

2011

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Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Nature (London), 2011-01, Vol.469 (7329), p.175-180

2011

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Backbone modification of a polypeptide drug alters duration of action in vivo

Nature biotechnology, 2014-07, Vol.32 (7), p.653-655

2014

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Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Biochemical pharmacology, 2017-07, Vol.136, p.99-108

2017

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Structure and function of an irreversible agonist-β2 adrenoceptor complex

Nature (London), 2011-01, Vol.469 (7329), p.236-240

2011

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Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon‑3 Polymers

Journal of the American Chemical Society, 2021-03, Vol.143 (8), p.3219-3230

2021

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Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli

PloS one, 2014-08, Vol.9 (8), p.e104500

2014

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Mimicry of Antimicrobial Host-Defense Peptides by Random Copolymers

Journal of the American Chemical Society, 2007-12, Vol.129 (50), p.15474-15476

2007

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Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (35), p.14751-14756

2009

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Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (15), p.4552-4557

2015

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Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR

Proceedings of the National Academy of Sciences - PNAS, 2020-03, Vol.117 (13), p.7455-7460

2020

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Local rigidification and possible coacervation of the Escherichia coli DNA by cationic nylon-3 polymers

Biophysical journal, 2021-12, Vol.120 (23), p.5243-5254

2021

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Diphenylprolinol Methyl Ether: A Highly Enantioselective Catalyst for Michael Addition of Aldehydes to Simple Enones

Organic letters, 2005-09, Vol.7 (19), p.4253-4256

2005

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Targeting protein-protein interactions: Lessons from p53/MDM2

Biopolymers, 2007, Vol.88 (5), p.657-686

2007

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Foldamer Catalysis

Journal of the American Chemical Society, 2020-10, Vol.142 (41), p.17211-17223

2020

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A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

Chemistry : a European journal, 2012-07, Vol.18 (31), p.9485-9490

2012

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Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly

Proceedings of the National Academy of Sciences - PNAS, 2008-07, Vol.105 (27), p.9151-9156

2008

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Foldamer-templated catalysis of macrocycle formation

Ketones from Nickel‐Catalyzed Decarboxylative, Non‐Symmetric Cross‐Electrophile Coupling of Carboxylic Acid Esters

Tailoring Reaction Selectivity by Modulating a Catalytic Diad on a Foldamer Scaffold

Modulation of hydrophobic interactions by proximally immobilized ions

Exploration of Diverse Reactive Diad Geometries for Bifunctional Catalysis via Foldamer Backbone Variation

Intranasal fusion inhibitory lipopeptide prevents direct-contact SARS-CoV-2 transmission in ferrets

Nylon‑3 Polymers Active against Drug-Resistant Candida albicans Biofilms

Versatile Open-Source Photoreactor Architecture for Photocatalysis Across the Visible Spectrum

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Backbone modification of a polypeptide drug alters duration of action in vivo

Characterization of signal bias at the GLP-1 receptor induced by backbone modification of GLP-1

Structure and function of an irreversible agonist-β2 adrenoceptor complex

Beyond Amphiphilic Balance: Changing Subunit Stereochemistry Alters the Pore-Forming Activity of Nylon‑3 Polymers

Medium effects on minimum inhibitory concentrations of nylon-3 polymers against E. coli

Mimicry of Antimicrobial Host-Defense Peptides by Random Copolymers

Structural and biological mimicry of protein surface recognition by α/β-peptide foldamers

Targeting diverse protein–protein interaction interfaces with α/β-peptides derived from the Z-domain scaffold

Gq/11-dependent regulation of endosomal cAMP generation by parathyroid hormone class B GPCR

Local rigidification and possible coacervation of the Escherichia coli DNA by cationic nylon-3 polymers

Diphenylprolinol Methyl Ether: A Highly Enantioselective Catalyst for Michael Addition of Aldehydes to Simple Enones

Targeting protein-protein interactions: Lessons from p53/MDM2

Foldamer Catalysis

A New Class of Amphiphiles Bearing Rigid Hydrophobic Groups for Solubilization and Stabilization of Membrane Proteins

Interplay among side chain sequence, backbone composition, and residue rigidification in polypeptide folding and assembly

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