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Silent agonists for α7 nicotinic acetylcholine receptors

Pharmacological research, 2023-04, Vol.190, p.106736-106736, Article 106736

2023

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A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE

Brain, behavior, and immunity, 2020-07, Vol.87, p.286-300

2020

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Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

European journal of medicinal chemistry, 2020-11, Vol.205, p.112669-112669, Article 112669

2020

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Allosteric Agonism of α 7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site

Molecular pharmacology, 2019-06, Vol.95 (6), p.606-614

2019

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Dissection of N,N-diethyl-N′-phenylpiperazines as α7 nicotinic receptor silent agonists

Bioorganic & medicinal chemistry, 2016-01, Vol.24 (2), p.286-293

2016

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Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds

Nicotine & tobacco research, 2019-05, Vol.21 (6), p.805-812

2019

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Macroscopic and Microscopic Activation of α 7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107

Molecular pharmacology, 2019-01, Vol.95 (1), p.43-61

2019

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Selective Agonists and Antagonists of α9 Versus α7 Nicotinic Acetylcholine Receptors

ACS chemical neuroscience, 2022-03, Vol.13 (5), p.624-637

2022

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Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy

Carbohydrate research, 2019-04, Vol.476, p.65-70

2019

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Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation

European journal of medicinal chemistry, 2018-12, Vol.160, p.207-228

2018

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Nicotinic acetylcholine receptor silent agonists modulate inflammation

The FASEB journal, 2019-04, Vol.33 (S1), p.lb236-lb236

2019

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Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site

Molecular pharmacology, 2019-06, Vol.95 (6), p.606-614

2019

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Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107

Molecular pharmacology, 2019-01, Vol.95 (1), p.43-61

2019

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Sulfonium as a Surrogate for Ammonium: A New α7 Nicotinic Acetylcholine Receptor Partial Agonist with Desensitizing Activity

Journal of medicinal chemistry, 2017-09, Vol.60 (18), p.7928-7934

2017

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Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

ChemMedChem, 2017-08, Vol.12 (16), p.1335-1348

2017

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Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

European journal of medicinal chemistry, 2016-01, Vol.108, p.392-405

2016

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Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

European journal of medicinal chemistry, 2014-03, Vol.75, p.222-232

2014

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Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

ChemMedChem, 2017-08, Vol.12 (16), p.1417-1417

2017

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Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ 2 ‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

ChemMedChem, 2017-08, Vol.12 (16), p.1417-1417

2017

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Back Cover: Identification of [alpha]7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-[Delta]2-Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

ChemMedChem, 2017-08, Vol.12 (16), p.1417

2017

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Identification of [alpha]7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-[Delta]2-Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

ChemMedChem, 2017-08, Vol.12 (16), p.1335

2017

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Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ 2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

ChemMedChem, 2017-08, Vol.12 (16), p.1335-1348

2017

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A convenient synthesis of 4-(2-hydroxyethyl)indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors

Monatshefte für Chemie, 2014-07, Vol.145 (7), p.1139-1144

2014

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Neurologic manifestations in 1760 COVID-19 patients admitted to Papa Giovanni XXIII Hospital, Bergamo, Italy

Journal of neurology, 2021-07, Vol.268 (7), p.2331-2338

2021

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Classification of neurologic outcomes from medical notes using natural language processing

Expert systems with applications, 2023-03, Vol.214, p.119171, Article 119171

2023

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Silent agonists for α7 nicotinic acetylcholine receptors

A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

Allosteric Agonism of α 7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site

Dissection of N,N-diethyl-N′-phenylpiperazines as α7 nicotinic receptor silent agonists

Cracking the Betel Nut: Cholinergic Activity of Areca Alkaloids and Related Compounds

Macroscopic and Microscopic Activation of α 7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107

Selective Agonists and Antagonists of α9 Versus α7 Nicotinic Acetylcholine Receptors

Synthesis of saccharin-glycoconjugates targeting carbonic anhydrase using a one-pot cyclization/deprotection strategy

Novel 5-(quinuclidin-3-ylmethyl)-1,2,4-oxadiazoles to investigate the activation of the α7 nicotinic acetylcholine receptor subtype: Synthesis and electrophysiological evaluation

Nicotinic acetylcholine receptor silent agonists modulate inflammation

Allosteric Agonism of α7 Nicotinic Acetylcholine Receptors: Receptor Modulation Outside the Orthosteric Site

Macroscopic and Microscopic Activation of α7 Nicotinic Acetylcholine Receptors by the Structurally Unrelated Allosteric Agonist-Positive Allosteric Modulators (ago-PAMs) B-973B and GAT107

Sulfonium as a Surrogate for Ammonium: A New α7 Nicotinic Acetylcholine Receptor Partial Agonist with Desensitizing Activity

Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

Modification of the anabaseine pyridine nucleus allows achieving binding and functional selectivity for the α3β4 nicotinic acetylcholine receptor subtype

Bis(ammonio)alkane-type agonists of muscarinic acetylcholine receptors: Synthesis, in vitro functional characterization, and in vivo evaluation of their analgesic activity

Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ2‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

Back Cover: Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine‐Δ 2 ‐Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation (ChemMedChem 16/2017)

Back Cover: Identification of [alpha]7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-[Delta]2-Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

Identification of [alpha]7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-[Delta]2-Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

Identification of α7 Nicotinic Acetylcholine Receptor Silent Agonists Based on the Spirocyclic Quinuclidine-Δ 2 -Isoxazoline Scaffold: Synthesis and Electrophysiological Evaluation

A convenient synthesis of 4-(2-hydroxyethyl)indolin-2-one, a useful intermediate for the preparation of both dopamine receptor agonists and protein kinase inhibitors

Neurologic manifestations in 1760 COVID-19 patients admitted to Papa Giovanni XXIII Hospital, Bergamo, Italy

Classification of neurologic outcomes from medical notes using natural language processing

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