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Merging old and new perspectives on nicotinic acetylcholine receptors

Biochemical pharmacology, 2014-05, Vol.89 (1), p.1-11

Papke, Roger L.

2014

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Nicotinic acetylcholine receptors: Conventional and unconventional ligands and signaling

Neuropharmacology, 2020-05, Vol.168, p.108021-108021, Article 108021

2020

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Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors

Pharmacological reviews, 2021-07, Vol.73 (3), p.1118-1149

2021

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Nicotinic Activity of Arecoline, the Psychoactive Element of "Betel Nuts", Suggests a Basis for Habitual Use and Anti-Inflammatory Activity

PloS one, 2015-10, Vol.10 (10), p.e0140907

2015

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Looking below the surface of nicotinic acetylcholine receptors

Trends in pharmacological sciences (Regular ed.), 2015-08, Vol.36 (8), p.514-523

2015

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Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

Biochemical pharmacology, 2011-10, Vol.82 (8), p.915-930

2011

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Silent agonists for α7 nicotinic acetylcholine receptors

Pharmacological research, 2023-04, Vol.190, p.106736-106736, Article 106736

2023

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New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs

Current neuropharmacology, 2018, Vol.16 (4), p.415-425

2018

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The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain

British journal of pharmacology, 2016-08, Vol.173 (16), p.2506-2520

2016

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Sulfonium Ligands of the α7 nAChR

Molecules (Basel, Switzerland), 2021-09, Vol.26 (18), p.5643

2021

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In Silico Modeling of the α7 Nicotinic Acetylcholine Receptor: New Pharmacological Challenges Associated with Multiple Modes of Signaling

Mini reviews in medicinal chemistry, 2020, Vol.20 (10), p.841

2020

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A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE

Brain, behavior, and immunity, 2020-07, Vol.87, p.286-300

2020

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Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain

CNS & neurological disorders drug targets, 2021, Vol.20 (4), p.366

2021

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Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

European journal of medicinal chemistry, 2020-11, Vol.205, p.112669-112669, Article 112669

2020

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The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal

Experimental neurology, 2019-10, Vol.320, p.113010-113010, Article 113010

2019

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The many enigmas of nicotine

Advances in pharmacology (1990), 2024, Vol.99, p.327

Papke, Roger L

2024

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Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice

PloS one, 2015, Vol.10 (1), p.e0116227-e0116227

2015

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Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes

The Journal of pharmacology and experimental therapeutics, 2010-05, Vol.333 (2), p.501

2010

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Therapeutic Targeting of α 7 Nicotinic Acetylcholine Receptors

Pharmacological reviews, 2021-07, Vol.73 (3), p.1118-1149

2021

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Insights Into the Differential Desensitization of α4β2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors

Molecular pharmacology, 2023-02, Vol.103 (2), p.63-76

2023

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Insights Into the Differential Desensitization of α 4 β 2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors

Molecular pharmacology, 2023-02, Vol.103 (2), p.63-76

2023

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The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

Toxins, 2021-08, Vol.13 (8), p.555

2021

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Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP

Frontiers in cellular neuroscience, 2022-03, Vol.16, p.779081-779081

2022

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The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice

Drug Discoveries & Therapeutics, 2017/08/31, Vol.11(4), pp.206-211

2017

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Cytisine-based nicotinic partial agonists as novel antidepressant compounds

The Journal of pharmacology and experimental therapeutics, 2009-04, Vol.329 (1), p.377

2009

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Merging old and new perspectives on nicotinic acetylcholine receptors

Nicotinic acetylcholine receptors: Conventional and unconventional ligands and signaling

Therapeutic Targeting of α7 Nicotinic Acetylcholine Receptors

Nicotinic Activity of Arecoline, the Psychoactive Element of "Betel Nuts", Suggests a Basis for Habitual Use and Anti-Inflammatory Activity

Looking below the surface of nicotinic acetylcholine receptors

Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: Advantages and limitations

Silent agonists for α7 nicotinic acetylcholine receptors

New Insights on Neuronal Nicotinic Acetylcholine Receptors as Targets for Pain and Inflammation: A Focus on α7 nAChRs

The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain

Sulfonium Ligands of the α7 nAChR

In Silico Modeling of the α7 Nicotinic Acetylcholine Receptor: New Pharmacological Challenges Associated with Multiple Modes of Signaling

A silent agonist of α7 nicotinic acetylcholine receptors modulates inflammation ex vivo and attenuates EAE

Effects of α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator on BDNF, NKCC1 and KCC2 Expression in the Hippocampus following Lipopolysaccharide-Induced Allodynia and Hyperalgesia in a Mouse Model of Inflammatory Pain

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

The α7 nicotinic receptor silent agonist R-47 prevents and reverses paclitaxel-induced peripheral neuropathy in mice without tolerance or altering nicotine reward and withdrawal

The many enigmas of nicotine

Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice

Activation and inhibition of mouse muscle and neuronal nicotinic acetylcholine receptors expressed in Xenopus oocytes

Therapeutic Targeting of α 7 Nicotinic Acetylcholine Receptors

Insights Into the Differential Desensitization of α4β2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors

Insights Into the Differential Desensitization of α 4 β 2 Nicotinic Acetylcholine Receptor Isoforms Obtained With Positive Allosteric Modulation of Mutant Receptors

The Allosteric Activation of α7 nAChR by α-Conotoxin MrIC Is Modified by Mutations at the Vestibular Site

Comparison of the Anti-inflammatory Properties of Two Nicotinic Acetylcholine Receptor Ligands, Phosphocholine and pCF3-diEPP

The α7 nicotinic acetylcholine receptor positive allosteric modulator attenuates lipopolysaccharide-induced activation of hippocampal IκB and CD11b gene expression in mice

Cytisine-based nicotinic partial agonists as novel antidepressant compounds

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