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Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

Archives of toxicology, 2017-08, Vol.91 (8), p.2849-2863

2017

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Variance component analysis of circulating miR-122 in serum from healthy human volunteers

PloS one, 2019-07, Vol.14 (7), p.e0220406-e0220406

2019

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Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers

The Journal of pharmacology and experimental therapeutics, 2015-03, Vol.352 (3), p.519

2015

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3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Clinical and translational science, 2021-09, Vol.14 (5), p.1659-1680

2021

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Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Molecular pharmacology, 2013-08, Vol.84 (2), p.182-189

2013

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Mechanisms underlying saturable intestinal absorption of metformin

Drug metabolism and disposition, 2008-08, Vol.36 (8), p.1650

2008

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Drug‐induced allergic hepatitis develops in mice when myeloid‐derived suppressor cells are depleted prior to halothane treatment

Hepatology (Baltimore, Md.), 2015-08, Vol.62 (2), p.546-557

2015

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Eosinophils mediate the pathogenesis of halothane‐induced liver injury in mice

Hepatology (Baltimore, Md.), 2013-05, Vol.57 (5), p.2026-2036

2013

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179

2013

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Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis

Journal of pharmaceutical sciences, 2016-02, Vol.105 (2), p.484-496

2016

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Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (16), p.6650-6655

2011

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Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer

PloS one, 2018-06, Vol.13 (6), p.e0198099

2018

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Histone demethylases UTX and JMJD3 are required for NKT cell development in mice

Cell & bioscience, 2017-05, Vol.7 (1), p.25-25, Article 25

2017

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Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry

Lab on a chip, 2020-01, Vol.2 (2), p.215-225

2020

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Selective inhibition of human cytochrome P4502C8 by montelukast

Drug metabolism and disposition, 2005-03, Vol.33 (3), p.413

2005

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Introduction to a manuscript series on the characterization and use of microphysiological systems (MPS) in pharmaceutical safety and ADME applications

Lab on a chip, 2020-03, Vol.20 (6), p.1049-1057

2020

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Research Review: Cholinergic mechanisms, early brain development, and risk for schizophrenia

Journal of child psychology and psychiatry, 2010-05, Vol.51 (5), p.535-549

2010

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Adenine Nucleotides Undergo Rapid, Quantitative Conversion to Adenosine in the Extracellular Space in Rat Hippocampus

The Journal of neuroscience, 1997-10, Vol.17 (20), p.7673-7682

1997

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In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk

Archives of toxicology, 2020-09, Vol.94 (9), p.3185-3200

2020

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Cigarette Smoke Exposure Greatly Increases Alcohol Consumption in Adolescent C57BL/6 Mice

Alcoholism, clinical and experimental research, 2013-01, Vol.37 (s1), p.E364-E372

2013

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Thymic stromal lymphopoietin and interleukin‐4 mediate the pathogenesis of halothane‐induced liver injury in mice

Hepatology (Baltimore, Md.), 2014-11, Vol.60 (5), p.1741-1752

2014

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Endogenous Interleukin-4 Regulates Glutathione Synthesis Following Acetaminophen-Induced Liver Injury in Mice

Chemical research in toxicology, 2012-01, Vol.25 (1), p.83-93

2012

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Utility of spherical human liver microtissues for prediction of clinical drug-induced liver injury

Variance component analysis of circulating miR-122 in serum from healthy human volunteers

Four cation-selective transporters contribute to apical uptake and accumulation of metformin in Caco-2 cell monolayers

3D cell culture models: Drug pharmacokinetics, safety assessment, and regulatory consideration

Organic cation transporter 1 (OCT1/mOct1) is localized in the apical membrane of Caco-2 cell monolayers and enterocytes

Mechanisms underlying saturable intestinal absorption of metformin

Drug‐induced allergic hepatitis develops in mice when myeloid‐derived suppressor cells are depleted prior to halothane treatment

Eosinophils mediate the pathogenesis of halothane‐induced liver injury in mice

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Why Does the Intestine Lack Basolateral Efflux Transporters for Cationic Compounds? A Provocative Hypothesis

Alcohol inhibition of the NMDA receptor function, long-term potentiation, and fear learning requires striatal-enriched protein tyrosine phosphatase

Interrogation of transcriptomic changes associated with drug-induced hepatic sinusoidal dilatation in colorectal cancer

Histone demethylases UTX and JMJD3 are required for NKT cell development in mice

Liver microphysiological systems development guidelines for safety risk assessment in the pharmaceutical industry

Selective inhibition of human cytochrome P4502C8 by montelukast

Introduction to a manuscript series on the characterization and use of microphysiological systems (MPS) in pharmaceutical safety and ADME applications

Research Review: Cholinergic mechanisms, early brain development, and risk for schizophrenia

Adenine Nucleotides Undergo Rapid, Quantitative Conversion to Adenosine in the Extracellular Space in Rat Hippocampus

In vitro assessment of farnesoid X receptor antagonism to predict drug-induced liver injury risk

Cigarette Smoke Exposure Greatly Increases Alcohol Consumption in Adolescent C57BL/6 Mice

Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Nav1.7 Inhibitors for the Treatment of Chronic Pain

Perspectives on the evaluation and adoption of complex in vitro models in drug development: Workshop with the FDA and the pharmaceutical industry (IQ MPS Affiliate)

Structure- and Ligand-Based Discovery of Chromane Arylsulfonamide Na v 1.7 Inhibitors for the Treatment of Chronic Pain

Thymic stromal lymphopoietin and interleukin‐4 mediate the pathogenesis of halothane‐induced liver injury in mice

Endogenous Interleukin-4 Regulates Glutathione Synthesis Following Acetaminophen-Induced Liver Injury in Mice

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