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Intestinal lymphatic transport for drug delivery

Advanced drug delivery reviews, 2011-09, Vol.63 (10), p.923-942

2011

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Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

Rapid communications in mass spectrometry, 2006-03, Vol.20 (6), p.965-972

2006

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Definitive Metabolite Identification Coupled with Automated Ligand Identification System (ALIS) Technology: A Novel Approach to Uncover Structure–Activity Relationships and Guide Drug Design in a Factor IXa Inhibitor Program

Journal of medicinal chemistry, 2016-03, Vol.59 (5), p.1818-1829

2016

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Qualification and application of an in vitro liver model early in pharmaceutical development to help derisk drug-induced liver injury (DILI)

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S42-S42

2019

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Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Bioorganic & medicinal chemistry letters, 2021-10, Vol.49, p.128314-128314, Article 128314

2021

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Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

Bioorganic & medicinal chemistry letters, 2020-09, Vol.30 (17), p.127390-127390, Article 127390

2020

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SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Bioorganic & medicinal chemistry letters, 2021-09, Vol.47, p.128214-128214, Article 128214

2021

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Discovery of novel BTK inhibitors with carboxylic acids

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1471-1477

2017

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Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3939-3943

2017

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Intestinal lymphatic transport for drug delivery: The Lymphatic System: Therapy, Imaging and Nanotechnology

Advanced drug delivery reviews, 2011, Vol.63 (10-11), p.923-942

2011

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Cremophor reduces paclitaxel penetration into bladder wall during intravesical treatment

Cancer chemotherapy and pharmacology, 1999, Vol.44 (3), p.241-248

1999

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In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin

Cell chemical biology, 2023-11, Vol.30 (11), p.1468

2023

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Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry

Drug metabolism letters, 2008-01, Vol.2 (1), p.1

2008

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Intestinal lymphatic transport for drug delivery

Matrix-assisted laser desorption/ionization imaging mass spectrometry for direct measurement of clozapine in rat brain tissue

Definitive Metabolite Identification Coupled with Automated Ligand Identification System (ALIS) Technology: A Novel Approach to Uncover Structure–Activity Relationships and Guide Drug Design in a Factor IXa Inhibitor Program

Qualification and application of an in vitro liver model early in pharmaceutical development to help derisk drug-induced liver injury (DILI)

Discovery of MK-1454: A Potent Cyclic Dinucleotide Stimulator of Interferon Genes Agonist for the Treatment of Cancer

Discovery of IDO1 inhibitors containing a decahydroquinoline, decahydro-1,6-naphthyridine, or octahydro-1H-pyrrolo[3,2-c]pyridine scaffold

Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing

Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

SAR towards indoline and 3-azaindoline classes of IDO1 inhibitors

Discovery of novel BTK inhibitors with carboxylic acids

Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

siRNA-Mediated Knockdown of P450 Oxidoreductase in Rats: A Tool to Reduce Metabolism by CYPs and Increase Exposure of High Clearance Compounds

Intestinal lymphatic transport for drug delivery: The Lymphatic System: Therapy, Imaging and Nanotechnology

Cremophor reduces paclitaxel penetration into bladder wall during intravesical treatment

In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin

Visualization of first-pass drug metabolism of terfenadine by MALDI-imaging mass spectrometry

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