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Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma

Cancer immunology research, 2020-04, Vol.8 (4), p.436-450

2020

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Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates

Journal of the American Chemical Society, 2016-02, Vol.138 (4), p.1430-1445

2016

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ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells

Molecular cancer research, 2021-04, Vol.19 (4), p.702-716

2021

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N-Desmethylclozapine, an Allosteric Agonist at Muscarinic 1 Receptor, Potentiates N-Methyl-D-Aspartate Receptor Activity

Proceedings of the National Academy of Sciences - PNAS, 2003-11, Vol.100 (23), p.13674-13679

2003

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A Molecular Basis for Nitric Oxide Sensing by Soluble Guanylate Cyclase

Proceedings of the National Academy of Sciences - PNAS, 1999-12, Vol.96 (26), p.14753-14758

1999

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Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

PloS one, 2015-12, Vol.10 (12), p.e0145151-e0145151

2015

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Inhibition of Soluble Guanylate Cyclase by ODQ

Biochemistry (Easton), 2000-09, Vol.39 (35), p.10848-10854

2000

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Revisiting the Kinetics of Nitric Oxide (NO) Binding to Soluble Guanylate Cyclase: The Simple NO-Binding Model Is Incorrect

Proceedings of the National Academy of Sciences - PNAS, 2002-09, Vol.99 (19), p.12097-12101

2002

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Phospho-N-Acetyl-Muramyl-Pentapeptide Translocase from Escherichia coli: Catalytic Role of Conserved Aspartic Acid Residues

Journal of Bacteriology, 2004-03, Vol.186 (6), p.1747-1757

2004

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Regulation of Gene Expression by Lithium and Depletion of Inositol in Slices of Adult Rat Cortex

Neuron (Cambridge, Mass.), 2005-03, Vol.45 (6), p.861-872

2005

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Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression

Oncotarget, 2022-12, Vol.13 (1), p.1350-1358

2022

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Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs

Bioconjugate chemistry, 2016-09, Vol.27 (9), p.2081-2088

2016

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Scintillation proximity assay of inositol phosphates in cell extracts: High-throughput measurement of G-protein-coupled receptor activation

Analytical biochemistry, 2003-02, Vol.313 (2), p.311-318

2003

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Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

Bioorganic & medicinal chemistry letters, 2020-09, Vol.30 (17), p.127390-127390, Article 127390

2020

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A Cell-Based Ultra-High-Throughput Screening Assay for Identifying Inhibitors of D-Amino Acid Oxidase

Journal of biomolecular screening, 2006-08, Vol.11 (5), p.481-487

2006

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Discovery of novel BTK inhibitors with carboxylic acids

Bioorganic & medicinal chemistry letters, 2017-03, Vol.27 (6), p.1471-1477

2017

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Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

Bioorganic & medicinal chemistry letters, 2017-08, Vol.27 (16), p.3939-3943

2017

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Correction to Inhibition of Soluble Guanylate Cyclase by ODQ

Biochemistry (Easton), 2012-11, Vol.51 (47), p.9593-9593

2012

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Discovery of selective glucocorticoid receptor modulator MK-5932

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (24), p.7374-7386

2011

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Development of a simplified assay for determination of the antimineralocorticoid activity of compounds dosed in rats

Journal of pharmacological and toxicological methods, 2008-03, Vol.57 (2), p.155-160

2008

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Interaction of Soluble Guanylate Cyclase with YC-1: Kinetic and Resonance Raman Studies

Biochemistry (Easton), 2000-04, Vol.39 (14), p.4191-4198

2000

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Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin

Biochemistry (Easton), 1998-12, Vol.37 (48), p.16898-16907

1998

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Cancer-Associated Fibroblasts Promote Immunosuppression by Inducing ROS-Generating Monocytic MDSCs in Lung Squamous Cell Carcinoma

Discovery of Pyrophosphate Diesters as Tunable, Soluble, and Bioorthogonal Linkers for Site-Specific Antibody–Drug Conjugates

ILT3 (LILRB4) Promotes the Immunosuppressive Function of Tumor-Educated Human Monocytic Myeloid-Derived Suppressor Cells

N-Desmethylclozapine, an Allosteric Agonist at Muscarinic 1 Receptor, Potentiates N-Methyl-D-Aspartate Receptor Activity

A Molecular Basis for Nitric Oxide Sensing by Soluble Guanylate Cyclase

Pharmacological Inhibition of O-GlcNAcase Does Not Increase Sensitivity of Glucocorticoid Receptor-Mediated Transrepression

Inhibition of Soluble Guanylate Cyclase by ODQ

Revisiting the Kinetics of Nitric Oxide (NO) Binding to Soluble Guanylate Cyclase: The Simple NO-Binding Model Is Incorrect

Phospho-N-Acetyl-Muramyl-Pentapeptide Translocase from Escherichia coli: Catalytic Role of Conserved Aspartic Acid Residues

Regulation of Gene Expression by Lithium and Depletion of Inositol in Slices of Adult Rat Cortex

Resistance of MMTV-NeuT/ATTAC mice to anti-PD-1 immune checkpoint therapy is associated with macrophage infiltration and Wnt pathway expression

Novel Phosphate Modified Cathepsin B Linkers: Improving Aqueous Solubility and Enhancing Payload Scope of ADCs

Scintillation proximity assay of inositol phosphates in cell extracts: High-throughput measurement of G-protein-coupled receptor activation

Development of Anti-CD74 Antibody–Drug Conjugates to Target Glucocorticoids to Immune Cells

Potent, non-covalent reversible BTK inhibitors with 8-amino-imidazo[1,5-a]pyrazine core featuring 3-position bicyclic ring substitutes

A Cell-Based Ultra-High-Throughput Screening Assay for Identifying Inhibitors of D-Amino Acid Oxidase

Discovery of novel BTK inhibitors with carboxylic acids

Discovery of 3-morpholino-imidazole[1,5-a]pyrazine BTK inhibitors for rheumatoid arthritis

Discovery of 8‑Amino-imidazo[1,5‑a]pyrazines as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis

The preclinical efficacy, selectivity and pharmacologic profile of MK-5932, an insulin-sparing selective glucocorticoid receptor modulator

Correction to Inhibition of Soluble Guanylate Cyclase by ODQ

Discovery of selective glucocorticoid receptor modulator MK-5932

Development of a simplified assay for determination of the antimineralocorticoid activity of compounds dosed in rats

Interaction of Soluble Guanylate Cyclase with YC-1: Kinetic and Resonance Raman Studies

Regeneration of the Ferrous Heme of Soluble Guanylate Cyclase from the Nitric Oxide Complex: Acceleration by Thiols and Oxyhemoglobin

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