UB Paderborn / Katalog / Suche / in CDI

Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Cell, 2013-04, Vol.153 (3), p.707-720

2013

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Transcriptional Architecture of the Primate Neocortex

Neuron (Cambridge, Mass.), 2012-03, Vol.73 (6), p.1083-1099

2012

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Understanding the effect of increased cell specific productivity on galactosylation of monoclonal antibodies produced using Chinese hamster ovary cells

Journal of biotechnology, 2021-03, Vol.329, p.92-103

2021

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Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging

PloS one, 2011-12, Vol.6 (12), p.e29610-e29610

2011

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Discovering Biology in Periodic Data through Phase Set Enrichment Analysis (PSEA)

Journal of biological rhythms, 2016-06, Vol.31 (3), p.244-257

2016

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Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline

Toxicological sciences, 2020-09, Vol.177 (1), p.121-139

2020

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Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors

Journal of clinical oncology, 2012-07, Vol.30 (19), p.2307-2313

2012

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Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis

Fluids and barriers of the CNS, 2018-05, Vol.15 (1), p.18-18, Article 18

2018

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Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities

Toxicological sciences, 2020-05, Vol.175 (1), p.98-112

2020

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Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury

Toxicological sciences, 2020-09, Vol.177 (1), p.281-299

2020

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Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation

Sleep (New York, N.Y.), 2014-10, Vol.37 (10), p.1589-1600

2014

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The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

Scientific reports, 2017-12, Vol.7 (1), p.17193-13, Article 17193

2017

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Effects of Long‐Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate

Journal of bone and mineral research, 2016-04, Vol.31 (4), p.839-851

2016

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Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake

Sleep (New York, N.Y.), 2017-06, Vol.40 (6)

2017

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Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

Scientific reports, 2020-05, Vol.10 (1), p.8374-8374, Article 8374

2020

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Toxicogenomics in drug development: a match made in heaven?

Expert opinion on drug metabolism & toxicology, 2016-08, Vol.12 (8), p.847-849

2016

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Qualification and application of an in vitro liver model early in pharmaceutical development to help derisk drug-induced liver injury (DILI)

Drug metabolism and pharmacokinetics, 2019-01, Vol.34 (1), p.S42-S42

2019

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Mechanism of Topology Simplification by Type II DNA Topoisomerases

Proceedings of the National Academy of Sciences - PNAS, 2001-03, Vol.98 (6), p.3045-3049

2001

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Reconstruction and Stability of Secondary Structure Elements in the Context of Protein Structure Prediction

Biophysical journal, 2009-06, Vol.96 (11), p.4399-4408

2009

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Learning about protein hydrogen bonding by minimizing contrastive divergence

Proteins, structure, function, and bioinformatics, 2007-02, Vol.66 (3), p.588-599

2007

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CRANKITE: A fast polypeptide backbone conformation sampler

Source code for biology and medicine, 2008-06, Vol.3 (1), p.12-12, Article 12

2008

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Exhaustive Metropolis Monte Carlo sampling and analysis of polyalanine conformations adopted under the influence of hydrogen bonds

Proteins, structure, function, and bioinformatics, 2005-10, Vol.61 (1), p.94-104

2005

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Comment on "Efficient Monte Carlo trial moves for polypeptide simulations" [ J. Chem. Phys. 123 , 174905 ( 2005 ) ]

The Journal of chemical physics, 2008-07, Vol.129 (2), p.027103-027103-2

2008

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Modeling HIV-1 integrase complexes based on their hydrodynamic properties

Biopolymers, 2003-01, Vol.68 (1), p.110-120

2003

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Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease

Transcriptional Architecture of the Primate Neocortex

Understanding the effect of increased cell specific productivity on galactosylation of monoclonal antibodies produced using Chinese hamster ovary cells

Molecular insights into the pathogenesis of Alzheimer's disease and its relationship to normal aging

Discovering Biology in Periodic Data through Phase Set Enrichment Analysis (PSEA)

Development and Application of a Transcriptomic Signature of Bioactivation in an Advanced In Vitro Liver Model to Reduce Drug-induced Liver Injury Risk Early in the Pharmaceutical Pipeline

Phase I Pharmacologic and Pharmacodynamic Study of the Gamma Secretase (Notch) Inhibitor MK-0752 in Adult Patients With Advanced Solid Tumors

Comparative transcriptomics of choroid plexus in Alzheimer's disease, frontotemporal dementia and Huntington's disease: implications for CSF homeostasis

Quantitative Transcriptional Biomarkers of Xenobiotic Receptor Activation in Rat Liver for the Early Assessment of Drug Safety Liabilities

Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury

Blood-gene expression reveals reduced circadian rhythmicity in individuals resistant to sleep deprivation

A Collaborative Initiative to Establish Genomic Biomarkers for Assessing Tumorigenic Potential to Reduce Reliance on Conventional Rodent Carcinogenicity Studies

The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

Effects of Long‐Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate

Transcriptional Profiling of Cholinergic Neurons From Basal Forebrain Identifies Changes in Expression of Genes Between Sleep and Wake

Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease

Toxicogenomics in drug development: a match made in heaven?

Qualification and application of an in vitro liver model early in pharmaceutical development to help derisk drug-induced liver injury (DILI)

Mechanism of Topology Simplification by Type II DNA Topoisomerases

Reconstruction and Stability of Secondary Structure Elements in the Context of Protein Structure Prediction

Learning about protein hydrogen bonding by minimizing contrastive divergence

CRANKITE: A fast polypeptide backbone conformation sampler

Exhaustive Metropolis Monte Carlo sampling and analysis of polyalanine conformations adopted under the influence of hydrogen bonds

Comment on "Efficient Monte Carlo trial moves for polypeptide simulations" [ J. Chem. Phys. 123 , 174905 ( 2005 ) ]

Modeling HIV-1 integrase complexes based on their hydrodynamic properties

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