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Nanobodies to Study G Protein-Coupled Receptor Structure and Function

Annual review of pharmacology and toxicology, 2017-01, Vol.57, p.19

2017

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A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

Neuron (Cambridge, Mass.), 2018-06, Vol.98 (5), p.963-976.e5

2018

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Nanobody stabilization of G protein-coupled receptor conformational states

Current opinion in structural biology, 2011-08, Vol.21 (4), p.567-572

2011

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Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer

Nature (London), 2019-01, Vol.565 (7740), p.516-520

2019

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The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

Cell, 2019-01, Vol.176 (3), p.435-447.e15

2019

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Activation and allosteric modulation of a muscarinic acetylcholine receptor

Nature (London), 2013-12, Vol.504 (7478), p.101-106

2013

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Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport

Nature structural & molecular biology, 2014-11, Vol.21 (11), p.990

2014

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Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes

Science (American Association for the Advancement of Science), 2015-10, Vol.350 (6257), p.178-178

2015

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Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

Nature (London), 2016-07, Vol.535 (7612), p.448-452

2016

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A general protocol for the generation of Nanobodies for structural biology

Nature protocols, 2014-03, Vol.9 (3), p.674-693

2014

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Structure, substrate recognition and initiation of hyaluronan synthase

Nature (London), 2022-04, Vol.604 (7904), p.195-201

2022

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Structure and function of the EA1 surface layer of Bacillus anthracis

Nature communications, 2023-11, Vol.14 (1), p.7051-7051, Article 7051

2023

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Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Cell, 2018-01, Vol.172 (1-2), p.55-67.e15

2018

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Crystal structure of the β2 adrenergic receptor-Gs protein complex

Nature (London), 2011-07, Vol.477 (7366), p.549-555

2011

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Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family

Nature structural & molecular biology, 2015-10, Vol.22 (10), p.803

2015

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Nanobody-enabled monitoring of kappa opioid receptor states

Nature communications, 2020-03, Vol.11 (1), p.1145-1145, Article 1145

2020

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Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Nature (London), 2016-07, Vol.535 (7610), p.182-186

2016

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Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Nature (London), 2011-01, Vol.469 (7329), p.175-180

2011

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Structure of Nanobody Nb23

Molecules (Basel, Switzerland), 2021-06, Vol.26 (12), p.3567

2021

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Advance care planning in dementia: recommendations for healthcare professionals

BMC palliative care, 2018-06, Vol.17 (1), p.88-88, Article 88

2018

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Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (33), p.13386-13391

2013

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Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

Nature methods, 2021-01, Vol.18 (1), p.60

2021

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Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Nature communications, 2018-05, Vol.9 (1), p.1996-15, Article 1996

2018

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Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (8), p.2984-2989

2014

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Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor

The Journal of immunology (1950), 2016-03, Vol.196 (6), p.2893-2901

2016

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Nanobodies to Study G Protein-Coupled Receptor Structure and Function

A Genetically Encoded Biosensor Reveals Location Bias of Opioid Drug Action

Nanobody stabilization of G protein-coupled receptor conformational states

Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer

The Molecular Mechanism of Transport by the Mitochondrial ADP/ATP Carrier

Activation and allosteric modulation of a muscarinic acetylcholine receptor

Crystal structure of a SLC11 (NRAMP) transporter reveals the basis for transition-metal ion transport

Structure and flexibility of the endosomal Vps34 complex reveals the basis of its function on membranes

Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation

A general protocol for the generation of Nanobodies for structural biology

Structure, substrate recognition and initiation of hyaluronan synthase

Structure and function of the EA1 surface layer of Bacillus anthracis

Structure of the Nanobody-Stabilized Active State of the Kappa Opioid Receptor

Crystal structure of the β2 adrenergic receptor-Gs protein complex

Structure of a prokaryotic fumarate transporter reveals the architecture of the SLC26 family

Nanobody-enabled monitoring of kappa opioid receptor states

Allosteric coupling from G protein to the agonist-binding pocket in GPCRs

Structure of a nanobody-stabilized active state of the β2 adrenoceptor

Structure of Nanobody Nb23

Advance care planning in dementia: recommendations for healthcare professionals

Structures of P-glycoprotein reveal its conformational flexibility and an epitope on the nucleotide-binding domain

Megabodies expand the nanobody toolkit for protein structure determination by single-particle cryo-EM

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Crystal structure of the proteasomal deubiquitylation module Rpn8-Rpn11

Development by Genetic Immunization of Monovalent Antibodies (Nanobodies) Behaving as Antagonists of the Human ChemR23 Receptor

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