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Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

PLoS pathogens, 2016-04, Vol.12 (4), p.e1005535-e1005535

2016

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Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (22), p.E2874-E2883

2015

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Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions

PLoS pathogens, 2016-08, Vol.12 (8), p.e1005679-e1005679

2016

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Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

PLoS computational biology, 2019-04, Vol.15 (4), p.e1006849-e1006849

2019

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Life cycle synchronization is a viral drug resistance mechanism

PLoS computational biology, 2018-02, Vol.14 (2), p.e1005947-e1005947

2018

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Clonal evolution of glioblastoma under therapy

Nature genetics, 2016-07, Vol.48 (7), p.768-776

2016

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Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

Cell, 2013-10, Vol.155 (3), p.540-551

2013

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Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

Proceedings of the National Academy of Sciences - PNAS, 2014-09, Vol.111 (37), p.13475-13480

2014

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Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines

Vaccines (Basel), 2023-09, Vol.11 (9), p.1501

2023

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Proliferation of latently infected CD4 + T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

The Journal of experimental medicine, 2017-04, Vol.214 (4), p.959-972

2017

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Re-evaluating evolution in the HIV reservoir

Nature (London), 2017-11, Vol.551 (7681), p.E6-E9

2017

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Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1

Science translational medicine, 2023-02, Vol.15 (684), p.eabn2038

2023

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Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

Open forum infectious diseases, 2015-12, Vol.2 (4), p.ofv123-ofv123

2015

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Evolutionary dynamics of HIV at multiple spatial and temporal scales

Journal of molecular medicine (Berlin, Germany), 2012-05, Vol.90 (5), p.543-561

2012

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Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations

The Journal of clinical investigation, 2015-05, Vol.125 (5), p.1901-1912

2015

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Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

PLoS pathogens, 2017-07, Vol.13 (7), p.e1006488-e1006488

2017

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Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

Nature (London), 2014-08, Vol.512 (7512), p.74-77

2014

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Measuring the Frequency of Latent HIV-1 in Resting CD4⁺ T Cells Using a Limiting Dilution Coculture Assay

Methods in molecular biology (Clifton, N.J.), 2016, Vol.1354, p.239

2016

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Insight into treatment of HIV infection from viral dynamics models

Immunological reviews, 2018-09, Vol.285 (1), p.9-25

2018

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Antiretroviral dynamics determines HIV evolution and predicts therapy outcome

Nature medicine, 2012-09, Vol.18 (9), p.1378-1385

2012

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Safety, efficacy, and immunogenicity of a replication-defective human cytomegalovirus vaccine, V160, in cytomegalovirus-seronegative women: a double-blind, randomised, placebo-controlled, phase 2b trial

The Lancet infectious diseases, 2023-12, Vol.23 (12), p.1383-1394

2023

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Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size

The Journal of infectious diseases, 2021-10, Vol.224 (7), p.1209-1218

2021

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Frequency-Dependent Selection Can Lead to Evolution of High Mutation Rates

The American naturalist, 2014-05, Vol.183 (5), p.E131-E153

2014

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Evolutionary scalpels for dissecting tumor ecosystems

Biochimica et biophysica acta. Reviews on cancer, 2017-04, Vol.1867 (2), p.69-83

2017

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Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination

Cell systems, 2016-07, Vol.3 (1), p.83-94

2016

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Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

Imperfect drug penetration leads to spatial monotherapy and rapid evolution of multidrug resistance

Insufficient Evidence for Rare Activation of Latent HIV in the Absence of Reservoir-Reducing Interventions

Assessing intra-lab precision and inter-lab repeatability of outgrowth assays of HIV-1 latent reservoir size

Life cycle synchronization is a viral drug resistance mechanism

Clonal evolution of glioblastoma under therapy

Replication-Competent Noninduced Proviruses in the Latent Reservoir Increase Barrier to HIV-1 Cure

Predicting the outcomes of treatment to eradicate the latent reservoir for HIV-1

Replicate Testing of Clinical Endpoints Can Prevent No-Go Decisions for Beneficial Vaccines

Proliferation of latently infected CD4 + T cells carrying replication-competent HIV-1: Potential role in latent reservoir dynamics

Re-evaluating evolution in the HIV reservoir

Potent targeted activator of cell kill molecules eliminate cells expressing HIV-1

Designing and Interpreting Limiting Dilution Assays: General Principles and Applications to the Latent Reservoir for Human Immunodeficiency Virus-1

Evolutionary dynamics of HIV at multiple spatial and temporal scales

Ex vivo analysis identifies effective HIV-1 latency-reversing drug combinations

Correction: Real-Time Predictions of Reservoir Size and Rebound Time during Antiretroviral Therapy Interruption Trials for HIV

Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys

Measuring the Frequency of Latent HIV-1 in Resting CD4⁺ T Cells Using a Limiting Dilution Coculture Assay

Insight into treatment of HIV infection from viral dynamics models

Antiretroviral dynamics determines HIV evolution and predicts therapy outcome

Safety, efficacy, and immunogenicity of a replication-defective human cytomegalovirus vaccine, V160, in cytomegalovirus-seronegative women: a double-blind, randomised, placebo-controlled, phase 2b trial

Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size

Frequency-Dependent Selection Can Lead to Evolution of High Mutation Rates

Evolutionary scalpels for dissecting tumor ecosystems

Topological Data Analysis Generates High-Resolution, Genome-wide Maps of Human Recombination

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