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Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling

Nature chemical biology, 2020-12, Vol.16 (12), p.1368-1375

2020

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The G Protein β -Subunit, AGB1, Interacts with FERONIA in RALF1-Regulated Stomatal Movement

Plant physiology (Bethesda), 2018-03, Vol.176 (3), p.2426-2440

2018

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Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Nature communications, 2018-05, Vol.9 (1), p.1996-15, Article 1996

2018

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Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs

Nature structural & molecular biology, 2021-03, Vol.28 (3), p.258-267

2021

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On the selectivity of the Gαq inhibitor UBO-QIC: A comparison with the Gαi inhibitor pertussis toxin

Biochemical pharmacology, 2016-05, Vol.107, p.59-66

2016

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Variable G protein determinants of GPCR coupling selectivity

Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (24), p.12054-12059

2019

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Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells

European journal of pharmacology, 2021-01, Vol.891, p.173706-173706, Article 173706

2021

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The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

Nature communications, 2013-05, Vol.4 (1), p.1829-1829, Article 1829

2013

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A Gq-Ca2+ Axis Controls Circuit-Level Encoding of Circadian Time in the Suprachiasmatic Nucleus

Neuron (Cambridge, Mass.), 2013-05, Vol.78 (4), p.714-728

2013

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Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Nature (London), 2021-01, Vol.589 (7840), p.148-153

2021

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Flexible functional interactions between G‐protein subunits contribute to the specificity of plant responses

The Plant journal : for cell and molecular biology, 2020-04, Vol.102 (2), p.207-221

2020

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The plant-specific G protein γ subunit AGG3 influences organ size and shape in Arabidopsis thaliana

The New phytologist, 2012-05, Vol.194 (3), p.690-703

2012

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Wnt-5a/Frizzled9 Receptor Signaling through the Gαo-Gβγ Complex Regulates Dendritic Spine Formation

The Journal of biological chemistry, 2016-09, Vol.291 (36), p.19092-19107

2016

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Invited review: Activation of G proteins by GTP and the mechanism of Gα‐catalyzed GTP hydrolysis

Biopolymers, 2016-08, Vol.105 (8), p.449-462

Sprang, Stephen R.

2016

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Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

Cell reports (Cambridge), 2021-06, Vol.35 (11), p.109246-109246, Article 109246

2021

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Translating G protein subunit diversity into functional specificity

Current opinion in cell biology, 2004-04, Vol.16 (2), p.206-209

2004

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Recruitment of Gβγ controls the basal activity of G‐protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1

The Journal of physiology, 2014-12, Vol.592 (24), p.5373-5390

2014

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Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

Nature communications, 2019-05, Vol.10 (1), p.2008-2008, Article 2008

2019

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The structure of the KtrAB potassium transporter

Nature (London), 2013-04, Vol.496 (7445), p.323-328

2013

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Disruption of the interaction between mutationally activated Gαq and Gβγ attenuates aberrant signaling

The Journal of biological chemistry, 2023-02, Vol.299 (2), p.102880-102880, Article 102880

2023

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Structural Diversity in the RGS Domain and Its Interaction with Heterotrimeric G Protein α-Subunits

Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (17), p.6457-6462

2008

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Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling

The Journal of biological chemistry, 2017-06, Vol.292 (23), p.9711-9720

2017

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Heterotrimeric G Proteins Facilitate Arabidopsis Resistance to Necrotrophic Pathogens and Are Involved in Jasmonate Signaling

Plant physiology (Bethesda), 2006-01, Vol.140 (1), p.210-220

2006

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Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

eLife, 2014-07, Vol.3, p.e03671-e03671

2014

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LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation

The Journal of biological chemistry, 2007-02, Vol.282 (7), p.4310

2007

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Sterols in an intramolecular channel of Smoothened mediate Hedgehog signaling

The G Protein β -Subunit, AGB1, Interacts with FERONIA in RALF1-Regulated Stomatal Movement

Targeting G protein-coupled receptor signaling at the G protein level with a selective nanobody inhibitor

Cryo-EM structure of an activated GPCR-G protein complex in lipid nanodiscs

On the selectivity of the Gαq inhibitor UBO-QIC: A comparison with the Gαi inhibitor pertussis toxin

Variable G protein determinants of GPCR coupling selectivity

Functional evidence for biased inhibition of G protein signaling by YM-254890 in human coronary artery endothelial cells

The gut microbiota suppresses insulin-mediated fat accumulation via the short-chain fatty acid receptor GPR43

A Gq-Ca2+ Axis Controls Circuit-Level Encoding of Circadian Time in the Suprachiasmatic Nucleus

Structure of the class D GPCR Ste2 dimer coupled to two G proteins

Flexible functional interactions between G‐protein subunits contribute to the specificity of plant responses

The plant-specific G protein γ subunit AGG3 influences organ size and shape in Arabidopsis thaliana

Wnt-5a/Frizzled9 Receptor Signaling through the Gαo-Gβγ Complex Regulates Dendritic Spine Formation

Invited review: Activation of G proteins by GTP and the mechanism of Gα‐catalyzed GTP hydrolysis

Extracellular succinate hyperpolarizes M2 macrophages through SUCNR1/GPR91-mediated Gq signaling

Translating G protein subunit diversity into functional specificity

Recruitment of Gβγ controls the basal activity of G‐protein coupled inwardly rectifying potassium (GIRK) channels: crucial role of distal C terminus of GIRK1

Structural mechanism underlying G protein family-specific regulation of G protein-gated inwardly rectifying potassium channel

The structure of the KtrAB potassium transporter

Disruption of the interaction between mutationally activated Gαq and Gβγ attenuates aberrant signaling

Structural Diversity in the RGS Domain and Its Interaction with Heterotrimeric G Protein α-Subunits

Disease-associated extracellular loop mutations in the adhesion G protein-coupled receptor G1 (ADGRG1; GPR56) differentially regulate downstream signaling

Heterotrimeric G Proteins Facilitate Arabidopsis Resistance to Necrotrophic Pathogens and Are Involved in Jasmonate Signaling

Quantitative analysis of mammalian GIRK2 channel regulation by G proteins, the signaling lipid PIP2 and Na+ in a reconstituted system

LPA(4)/GPR23 is a lysophosphatidic acid (LPA) receptor utilizing G(s)-, G(q)/G(i)-mediated calcium signaling and G(12/13)-mediated Rho activation

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