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Homing in: Mechanisms of Substrate Targeting by Protein Kinases

Trends in biochemical sciences (Amsterdam. Regular ed.), 2018-05, Vol.43 (5), p.380-394

2018

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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Molecular cell, 2015-07, Vol.59 (2), p.285-297

2015

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The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover

PloS one, 2010-11, Vol.5 (11), p.e13935-e13935

2010

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Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

Molecular cell, 2014-02, Vol.53 (3), p.471-483

2014

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The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice

Cell host & microbe, 2014-05, Vol.15 (5), p.537-550

2014

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Manipulation of host signalling pathways by anthrax toxins

Biochemical journal, 2007-03, Vol.402 (3), p.405-417

Turk, Benjamin E

2007

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Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

Cell, 2015-09, Vol.163 (1), p.202-217

2015

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An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential

Molecular cell, 2014-08, Vol.55 (3), p.436-450

2014

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Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases

Molecular cell, 2016-05, Vol.62 (3), p.397-408

2016

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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

PLoS biology, 2019-03, Vol.17 (3), p.e2006540

2019

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Molecular cell, 2008-04, Vol.30 (2), p.214-226

2008

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Stratification of risk of early-onset sepsis in newborns ≥ 34 weeks' gestation

Pediatrics (Evanston), 2014-01, Vol.133 (1), p.30

2014

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An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells

Nature communications, 2023-06, Vol.14 (1), p.3803-3803, Article 3803

2023

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Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

Biochemical journal, 2009-10, Vol.424 (1), p.79-88

2009

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Glycogen synthase kinase‐3β regulation: another kinase gets in on the AKT

FEBS letters, 2018-02, Vol.592 (4), p.535-536

Turk, Benjamin E.

2018

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Unmasking Determinants of Specificity in the Human Kinome

Cell, 2015-09, Vol.163 (1), p.187-201

2015

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Autoregulation of the LIM kinases by their PDZ domain

Nature communications, 2023-12, Vol.14 (1), p.8441-8441, Article 8441

2023

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Linear motif specificity in signaling through p38α and ERK2 mitogen-activated protein kinases

Proceedings of the National Academy of Sciences - PNAS, 2023-11, Vol.120 (48), p.e2316599120

2023

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mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

Science (American Association for the Advancement of Science), 2013-07, Vol.341 (6144), p.364-364

2013

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Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

Biochemistry (Easton), 2014-09, Vol.53 (34), p.5579-5587

2014

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Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Molecular cell, 2014-01, Vol.53 (1), p.140-147

2014

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Control of serotonin transporter phosphorylation by conformational state

Proceedings of the National Academy of Sciences - PNAS, 2016-05, Vol.113 (20), p.E2776-E2783

2016

Volltextzugriff (PDF)

Reciprocal Phosphorylation of Yeast Glycerol-3-Phosphate Dehydrogenases in Adaptation to Distinct Types of Stress

Molecular and Cellular Biology, 2012-11, Vol.32 (22), p.4705-4717

2012

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Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

Nature communications, 2022-02, Vol.13 (1), p.749-749, Article 749

2022

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PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

Cell reports (Cambridge), 2021-03, Vol.34 (13), p.108928-108928, Article 108928

2021

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Homing in: Mechanisms of Substrate Targeting by Protein Kinases

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover

Early Steps in Autophagy Depend on Direct Phosphorylation of Atg9 by the Atg1 Kinase

The Toxoplasma Pseudokinase ROP5 Forms Complexes with ROP18 and ROP17 Kinases that Synergize to Control Acute Virulence in Mice

Manipulation of host signalling pathways by anthrax toxins

Kinome-wide Decoding of Network-Attacking Mutations Rewiring Cancer Signaling

An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential

Structural Basis for Noncanonical Substrate Recognition of Cofilin/ADF Proteins by LIM Kinases

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Stratification of risk of early-onset sepsis in newborns ≥ 34 weeks' gestation

An optogenetic-phosphoproteomic study reveals dynamic Akt1 signaling profiles in endothelial cells

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

Glycogen synthase kinase‐3β regulation: another kinase gets in on the AKT

Unmasking Determinants of Specificity in the Human Kinome

Autoregulation of the LIM kinases by their PDZ domain

Linear motif specificity in signaling through p38α and ERK2 mitogen-activated protein kinases

mTORC1 Phosphorylation Sites Encode Their Sensitivity to Starvation and Rapamycin

Identification of Cleavage Sites Leading to the Shed Form of the Anti-Aging Protein Klotho

Identification of a Major Determinant for Serine-Threonine Kinase Phosphoacceptor Specificity

Control of serotonin transporter phosphorylation by conformational state

Reciprocal Phosphorylation of Yeast Glycerol-3-Phosphate Dehydrogenases in Adaptation to Distinct Types of Stress

Tousled-like kinase 2 targets ASF1 histone chaperones through client mimicry

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

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