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Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Molecular cell, 2015-03, Vol.57 (5), p.860-872

2015

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Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

eLife, 2019-05, Vol.8

2019

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Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks

Nature communications, 2022-09, Vol.13 (1), p.5295-5295, Article 5295

2022

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Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks

Frontiers in genetics, 2022-02, Vol.12, p.809832-809832

2022

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NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

Oncogene, 2020-07, Vol.39 (30), p.5252-5266

2020

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RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells

Cell reports (Cambridge), 2024-04, Vol.43 (4), p.114116-114116, Article 114116

2024

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ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest

Cell systems, 2019-02, Vol.8 (2), p.163-167.e2

2019

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Ubiquitination by the Membrane-associated RING-CH-8 (MARCH-8) Ligase Controls Steady-state Cell Surface Expression of Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL) Receptor 1[S]

The Journal of biological chemistry, 2013-03, Vol.288 (9), p.6617-6628

2013

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N-terminal acetylation can stabilize proteins independent of their ubiquitination

Scientific reports, 2023-04, Vol.13 (1), p.5333-5333, Article 5333

2023

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Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

PLoS biology, 2019-03, Vol.17 (3), p.e2006540

2019

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FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

Cell reports (Cambridge), 2023-07, Vol.42 (7), p.112668-112668, Article 112668

2023

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Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Molecular cell, 2015-06, Vol.58 (5), p.900-900

2015

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An atlas of substrate specificities for the human serine/threonine kinome

Nature (London), 2023-01, Vol.613 (7945), p.759-766

2023

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Proteasome Activation by Small Molecules

Cell chemical biology, 2017-06, Vol.24 (6), p.725-736.e7

2017

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Antiapoptotic potency of Bcl-2 proteins primarily relies on their stability, not binding selectivity

Blood, 2014-05, Vol.123 (18), p.2806-2815

2014

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EXO1 protects BRCA1-deficient cells against toxic DNA lesions

Molecular cell, 2024-02, Vol.84 (4), p.659-674.e7

2024

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Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology

Cell death & disease, 2019-01, Vol.10 (2), p.45-45, Article 45

2019

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Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

Journal of neuroinflammation, 2012-06, Vol.9 (1), p.133-133, Article 133

2012

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Disturbed function of the blood–cerebrospinal fluid barrier aggravates neuro-inflammation

Acta neuropathologica, 2014-08, Vol.128 (2), p.267-277

2014

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MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis

The Journal of neuroscience, 2013-04, Vol.33 (16), p.6857-6863

2013

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Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury

Intensive care medicine, 2023-05, Vol.49 (5), p.491-504

2023

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Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis

Journal of neuroinflammation, 2024-03, Vol.21 (1), p.72-72

2024

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Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis

Brain (London, England : 1878), 2011-02, Vol.134 (Pt 2), p.555-570

2011

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Etomidate versus Ketamine as Prehospital Induction Agent in Patients with Suspected Severe Traumatic Brain Injury

Anesthesiology (Philadelphia), 2024-04, Vol.140 (4), p.742

2024

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Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

Comprehensive substrate specificity profiling of the human Nek kinome reveals unexpected signaling outputs

Multi-pathway DNA-repair reporters reveal competition between end-joining, single-strand annealing and homologous recombination at Cas9-induced DNA double-strand breaks

Genomic Reporter Constructs to Monitor Pathway-Specific Repair of DNA Double-Strand Breaks

NEK10 tyrosine phosphorylates p53 and controls its transcriptional activity

RAD52-dependent mitotic DNA synthesis is required for genome stability in Cyclin E1-overexpressing cells

ROS and Oxidative Stress Are Elevated in Mitosis during Asynchronous Cell Cycle Progression and Are Exacerbated by Mitotic Arrest

Ubiquitination by the Membrane-associated RING-CH-8 (MARCH-8) Ligase Controls Steady-state Cell Surface Expression of Tumor Necrosis Factor-related Apoptosis Inducing Ligand (TRAIL) Receptor 1[S]

N-terminal acetylation can stabilize proteins independent of their ubiquitination

Comprehensive profiling of the STE20 kinase family defines features essential for selective substrate targeting and signaling output

FIRRM/C1orf112 is synthetic lethal with PICH and mediates RAD51 dynamics

Limited Mitochondrial Permeabilization Causes DNA Damage and Genomic Instability in the Absence of Cell Death

An atlas of substrate specificities for the human serine/threonine kinome

Proteasome Activation by Small Molecules

Antiapoptotic potency of Bcl-2 proteins primarily relies on their stability, not binding selectivity

EXO1 protects BRCA1-deficient cells against toxic DNA lesions

Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology

Sphingosine 1-phosphate receptor 5 mediates the immune quiescence of the human brain endothelial barrier

Disturbed function of the blood–cerebrospinal fluid barrier aggravates neuro-inflammation

MicroRNAs regulate human brain endothelial cell-barrier function in inflammation: implications for multiple sclerosis

Association between prehospital end-tidal carbon dioxide levels and mortality in patients with suspected severe traumatic brain injury

Inflammation-induced TRPV4 channels exacerbate blood-brain barrier dysfunction in multiple sclerosis

Specialized pro-resolving lipid mediators are differentially altered in peripheral blood of patients with multiple sclerosis and attenuate monocyte and blood-brain barrier dysfunction

Adenosine triphosphate-binding cassette transporters mediate chemokine (C-C motif) ligand 2 secretion from reactive astrocytes: relevance to multiple sclerosis pathogenesis

Etomidate versus Ketamine as Prehospital Induction Agent in Patients with Suspected Severe Traumatic Brain Injury

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