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AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

Molecular cell, 2017-06, Vol.66 (6), p.789-800

2017

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AMPK: restoring metabolic homeostasis over space and time

Molecular cell, 2021-09, Vol.81 (18), p.3677-3690

2021

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Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Molecular cell, 2015-07, Vol.59 (2), p.285-297

2015

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Autophagic cell death restricts chromosomal instability during replicative crisis

Nature (London), 2019-01, Vol.565 (7741), p.659-663

2019

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AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

Cell metabolism, 2011-04, Vol.13 (4), p.376-388

2011

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LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

Cancer cell, 2013-02, Vol.23 (2), p.143-158

2013

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AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6270), p.275-281

2016

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Transcriptional Coregulators: Fine-Tuning Metabolism

Cell metabolism, 2014-07, Vol.20 (1), p.26-40

2014

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Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

Cell metabolism, 2017-02, Vol.25 (2), p.463-471

2017

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mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

Cell metabolism, 2013-11, Vol.18 (5), p.726-739

2013

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Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

Cell, 2011-05, Vol.145 (4), p.607-621

2011

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Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

Cell, 2016-05, Vol.165 (5), p.1209-1223

2016

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Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

Nature medicine, 2016-10, Vol.22 (10), p.1108-1119

2016

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The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

Autophagy, 2011-06, Vol.7 (6), p.643-644

2011

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Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction

Cell metabolism, 2015-11, Vol.22 (5), p.907-921

2015

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AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes

Genes & development, 2016-03, Vol.30 (5), p.535-552

2016

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AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Molecular cell, 2008-04, Vol.30 (2), p.214-226

2008

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Science (American Association for the Advancement of Science), 2011-01, Vol.331 (6016), p.456-461

2011

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Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD

Cell reports (Cambridge), 2019-01, Vol.26 (1), p.192-208.e6

2019

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An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential

Molecular cell, 2014-08, Vol.55 (3), p.436-450

2014

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A Hormone-Dependent Module Regulating Energy Balance

Cell, 2011-05, Vol.145 (4), p.596-606

2011

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Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

Nature (London), 2011-02, Vol.470 (7334), p.404-408

2011

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Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (7), p.2554-2559

2014

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Metabolic reprogramming by class I and II histone deacetylases

Trends in endocrinology and metabolism, 2013-01, Vol.24 (1), p.48-57

2013

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AMPK Keeps Tumor Cells from Starving to Death

Cell stem cell, 2015-11, Vol.17 (5), p.503-504

Shaw, Reuben J.

2015

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AMPK: Mechanisms of Cellular Energy Sensing and Restoration of Metabolic Balance

AMPK: restoring metabolic homeostasis over space and time

Small Molecule Inhibition of the Autophagy Kinase ULK1 and Identification of ULK1 Substrates

Autophagic cell death restricts chromosomal instability during replicative crisis

AMPK Phosphorylates and Inhibits SREBP Activity to Attenuate Hepatic Steatosis and Atherosclerosis in Diet-Induced Insulin-Resistant Mice

LKB1 Inactivation Dictates Therapeutic Response of Non-Small Cell Lung Cancer to the Metabolism Drug Phenformin

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

Transcriptional Coregulators: Fine-Tuning Metabolism

Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex

mTOR Complex 2 Controls Glycolytic Metabolism in Glioblastoma through FoxO Acetylation and Upregulation of c-Myc

Class IIa Histone Deacetylases Are Hormone-Activated Regulators of FOXO and Mammalian Glucose Homeostasis

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models

The autophagy initiating kinase ULK1 is regulated via opposing phosphorylation by AMPK and mTOR

Identification of AMPK Phosphorylation Sites Reveals a Network of Proteins Involved in Cell Invasion and Facilitates Large-Scale Substrate Prediction

AMPK governs lineage specification through Tfeb-dependent regulation of lysosomes

AMPK Phosphorylation of Raptor Mediates a Metabolic Checkpoint

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Genetic Liver-Specific AMPK Activation Protects against Diet-Induced Obesity and NAFLD

An AMPK-Independent Signaling Pathway Downstream of the LKB1 Tumor Suppressor Controls Snail1 and Metastatic Potential

A Hormone-Dependent Module Regulating Energy Balance

Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB

Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1α

Metabolic reprogramming by class I and II histone deacetylases

AMPK Keeps Tumor Cells from Starving to Death

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