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Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

The Journal of cell biology, 2008-10, Vol.183 (1), p.101-116

2008

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Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis

Breast cancer research and treatment, 2017-08, Vol.164 (3), p.581-591

2017

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Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

Cancer research (Chicago, Ill.), 2006-01, Vol.66 (2), p.999-1006

2006

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Hyaluronan and morphogenesis

Birth defects research. Part C. Embryo today, 2004-03, Vol.72 (1), p.89-108

2004

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Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns

Developmental dynamics, 2005-05, Vol.233 (1), p.130-141

2005

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An Antibody-Drug Conjugate Targeting the Endothelin B Receptor for the Treatment of Melanoma

Clinical cancer research, 2011-03, Vol.17 (5), p.965-975

2011

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Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma

Cancer chemotherapy and pharmacology, 2012-04, Vol.69 (4), p.1071-1078

2012

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Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake

Molecular cancer therapeutics, 2008-09, Vol.7 (9), p.2599-2608

2008

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Regulation of ERK3/MAPK6 expression by BRAF

International journal of oncology, 2006-10, Vol.29 (4), p.839-849

2006

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Expression of interleukin-17B in mouse embryonic limb buds and regulation by BMP-7 and bFGF

Biochemical and biophysical research communications, 2005-01, Vol.326 (3), p.624-631

2005

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Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAFV600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway Suppression

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.3042-3051

2009

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Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

The Journal of clinical investigation, 2009-05, Vol.119 (5), p.1216-1229

2009

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Site-Specific Trastuzumab Maytansinoid Antibody–Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering

Journal of medicinal chemistry, 2014-10, Vol.57 (19), p.7890-7899

2014

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MMP-1 and Pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer

Clinical cancer research, 2014-12, Vol.20 (24), p.6324-6335

2014

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Abstract 2162: Inhibition of pancreatic cancer cell and tumor growth using MET inhibitors in combination with inhibitors of downstream signaling mediators, MEK and PI3K

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.2162-2162

2013

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Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

Science translational medicine, 2013-02, Vol.5 (171), p.171ra18

2013

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Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity

Molecular cancer therapeutics, 2015-10, Vol.14 (10), p.2270-2278

2015

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Abstract B22: Potential combinatorial strategies to overcome drug resistance in BRAF-mutant melanoma

Clinical cancer research, 2015-02, Vol.21 (4_Supplement), p.B22-B22

2015

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Abstract 3690: MMP-1 and pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.3690-3690

2014

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Investigation of hyaluronan function in the mouse through targeted mutagenesis

Glycoconjugate journal, 2002-05, Vol.19 (4-5), p.341-345

2002

Volltextzugriff (PDF)

Abstract C63: Targeting FGFR3 with monoclonal antibody impairs bladder cancer growth in vivo

Molecular cancer therapeutics, 2011-11, Vol.10 (11_Supplement), p.C63-C63

2011

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Abstract 4289: Early study on LGR5/GPR49 molecule as a potential colon cancer stem cell target for the antibody conjugated drug treatment

Cancer research (Chicago, Ill.), 2010-04, Vol.70 (8_Supplement), p.4289-4289

2010

Volltextzugriff (PDF)

Investigation of hyaluronan and hyaluronan synthase function during mouse development

Tien, Janet Yuetsim Lee

2004

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Molecular Genetic Dissection of Hyaluronan Function in the Mouse

Chemistry and Biology of Hyaluronan, 2004

2004

Volltextzugriff (PDF)

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Akt inhibition promotes autophagy and sensitizes PTEN-null tumors to lysosomotropic agents

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

Hyaluronan and morphogenesis

Three vertebrate hyaluronan synthases are expressed during mouse development in distinct spatial and temporal patterns

An Antibody-Drug Conjugate Targeting the Endothelin B Receptor for the Treatment of Melanoma

Preclinical pharmacokinetics of MFGR1877A, a human monoclonal antibody to FGFR3, and prediction of its efficacious clinical dose for the treatment of t(4;14)-positive multiple myeloma

Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake

Regulation of ERK3/MAPK6 expression by BRAF

Expression of interleukin-17B in mouse embryonic limb buds and regulation by BMP-7 and bFGF

Conjugation site modulates the in vivo stability and therapeutic activity of antibody-drug conjugates

Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAFV600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway Suppression

Antibody-based targeting of FGFR3 in bladder carcinoma and t(4;14)-positive multiple myeloma in mice

Site-Specific Trastuzumab Maytansinoid Antibody–Drug Conjugates with Improved Therapeutic Activity through Linker and Antibody Engineering

MMP-1 and Pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer

Abstract 2162: Inhibition of pancreatic cancer cell and tumor growth using MET inhibitors in combination with inhibitors of downstream signaling mediators, MEK and PI3K

Blocking NRG1 and other ligand-mediated Her4 signaling enhances the magnitude and duration of the chemotherapeutic response of non-small cell lung cancer

Redesigning a Monospecific Anti-FGFR3 Antibody to Add Selectivity for FGFR2 and Expand Antitumor Activity

Abstract B22: Potential combinatorial strategies to overcome drug resistance in BRAF-mutant melanoma

Abstract 3690: MMP-1 and pro-MMP-10 as potential urinary pharmacodynamic biomarkers of FGFR3-targeted therapy in patients with bladder cancer

Investigation of hyaluronan function in the mouse through targeted mutagenesis

Abstract C63: Targeting FGFR3 with monoclonal antibody impairs bladder cancer growth in vivo

Abstract 4289: Early study on LGR5/GPR49 molecule as a potential colon cancer stem cell target for the antibody conjugated drug treatment

Investigation of hyaluronan and hyaluronan synthase function during mouse development

Molecular Genetic Dissection of Hyaluronan Function in the Mouse

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