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Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity

The Journal of immunology (1950), 2014-03, Vol.192 (5), p.2252-2260

2014

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Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies

Nature communications, 2023-11, Vol.14 (1), p.7888-7888, Article 7888

2023

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Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

eLife, 2023-12, Vol.12

2023

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The Endoplasmic Reticulum-resident Heat Shock Protein Gp96 Activates Dendritic Cells via the Toll-like Receptor 2/4 Pathway

The Journal of biological chemistry, 2002-06, Vol.277 (23), p.20847-20853

2002

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Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

Biochemical journal, 2005-08, Vol.390 (Pt 1), p.125-136

2005

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A Bicyclic Autotrophic CO2 Fixation Pathway in Chloroflexus aurantiacus

The Journal of biological chemistry, 2002-06, Vol.277 (23), p.20277-20283

2002

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Cytomegalovirus Encodes a Positive Regulator of Antigen Presentation

Journal of Virology, 2006-08, Vol.80 (15), p.7613-7624

2006

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Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

Protein engineering, design and selection, 2016-10, Vol.29 (10), p.457-466

2016

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l-Malyl-Coenzyme A Lyase/β-Methylmalyl-Coenzyme A Lyase from Chloroflexus aurantiacus, a Bifunctional Enzyme Involved in Autotrophic CO2 Fixation

Journal of Bacteriology, 2002-11, Vol.184 (21), p.5999-6006

2002

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Pharmacologic Inhibitors of STAT3 or BCL6 Transcriptional Function Sensitize Lymphoma Cells to the Novel PD-1 Cis-Targeted PD1-IL2v Immunocytokine in a Murine Model

Blood, 2022-11, Vol.140 (Supplement 1), p.8835-8836

2022

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CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

Clinical cancer research, 2018-10, Vol.24 (19), p.4785-4797

2018

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Autotrophic CO2 Fixation by Chloroflexus aurantiacus: Study of Glyoxylate Formation and Assimilation via the 3-Hydroxypropionate Cycle

Journal of Bacteriology, 2001-07, Vol.183 (14), p.4305-4316

2001

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Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models

Molecular cancer therapeutics, 2013-10, Vol.12 (10), p.2031-2042

2013

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A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

Cancer Immunology, Immunotherapy, 2017-01, Vol.66 (1), p.129-140

2017

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FcγRIIIa chromatography to enrich a-fucosylated glycoforms and assess the potency of glycoengineered therapeutic antibodies

Journal of Chromatography A, 2020-01, Vol.1610, p.460554, Article 460554

2020

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TMIC-77. SINGLE-CELL CHARACTERIZATION OF HUMAN GBM REVEALS REGIONAL DIFFERENCES IN TUMOR-INFILTRATING LEUKOCYTE ACTIVATION

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii288-vii289

2022

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Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

eLife, 2023-12, Vol.12

2023

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Ibrutinib-based therapy reinvigorates CD8+ T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial

Blood, 2024-01, Vol.143 (1), p.57

2024

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Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAFV600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway Suppression

Cancer research (Chicago, Ill.), 2009-04, Vol.69 (7), p.3042-3051

2009

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RG6076 (CD19-4-1BBL): CD19-Targeted 4-1BB Ligand Combination with Glofitamab As an Off-the-Shelf, Enhanced T-Cell Redirection Therapy for B-Cell Malignancies

Blood, 2020-11, Vol.136 (Supplement 1), p.40-40

2020

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A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis

The AAPS journal, 2021-12, Vol.24 (1), p.7, Article 7

2021

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Glycoengineering of therapeutic antibodies enhances monocyte/macrophage-mediated phagocytosis and cytotoxicity

Explainable machine learning for profiling the immunological synapse and functional characterization of therapeutic antibodies

Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

The Endoplasmic Reticulum-resident Heat Shock Protein Gp96 Activates Dendritic Cells via the Toll-like Receptor 2/4 Pathway

Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers

A Bicyclic Autotrophic CO2 Fixation Pathway in Chloroflexus aurantiacus

Cytomegalovirus Encodes a Positive Regulator of Antigen Presentation

Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

l-Malyl-Coenzyme A Lyase/β-Methylmalyl-Coenzyme A Lyase from Chloroflexus aurantiacus, a Bifunctional Enzyme Involved in Autotrophic CO2 Fixation

Novel Tumor-Targeted, Engineered IL-2 Variant (IL2v)-Based Immunocytokines For Immunotherapy Of Cancer

Pharmacologic Inhibitors of STAT3 or BCL6 Transcriptional Function Sensitize Lymphoma Cells to the Novel PD-1 Cis-Targeted PD1-IL2v Immunocytokine in a Murine Model

CD20-TCB with Obinutuzumab Pretreatment as Next-Generation Treatment of Hematologic Malignancies

Autotrophic CO2 Fixation by Chloroflexus aurantiacus: Study of Glyoxylate Formation and Assimilation via the 3-Hydroxypropionate Cycle

Preclinical activity of the type II CD20 antibody GA101 (obinutuzumab) compared with rituximab and ofatumumab in vitro and in xenograft models

PD-1-cis IL-2R agonism yields better effectors from stem-like CD8 + T cells

A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents

FcγRIIIa chromatography to enrich a-fucosylated glycoforms and assess the potency of glycoengineered therapeutic antibodies

Venetoclax plus R- or G-CHOP in non-Hodgkin lymphoma: results from the CAVALLI phase 1b trial

Increasing the efficacy of CD20 antibody therapy through the engineering of a new type II anti-CD20 antibody with enhanced direct and immune effector cell–mediated B-cell cytotoxicity

TMIC-77. SINGLE-CELL CHARACTERIZATION OF HUMAN GBM REVEALS REGIONAL DIFFERENCES IN TUMOR-INFILTRATING LEUKOCYTE ACTIVATION

Single-cell characterization of human GBM reveals regional differences in tumor-infiltrating leukocyte activation

Ibrutinib-based therapy reinvigorates CD8+ T cells compared to chemoimmunotherapy: immune monitoring from the E1912 trial

Antitumor Efficacy of the Novel RAF Inhibitor GDC-0879 Is Predicted by BRAFV600E Mutational Status and Sustained Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase Pathway Suppression

RG6076 (CD19-4-1BBL): CD19-Targeted 4-1BB Ligand Combination with Glofitamab As an Off-the-Shelf, Enhanced T-Cell Redirection Therapy for B-Cell Malignancies

A Novel Approach for Quantifying the Pharmacological Activity of T-Cell Engagers Utilizing In Vitro Time Course Experiments and Streamlined Data Analysis

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