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Donated chemical probes for open science

eLife, 2018-04, Vol.7

2018

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Public-Private Partnerships in Lead Discovery: Overview and Case Studies

Archiv der Pharmazie (Weinheim), 2016-09, Vol.349 (9), p.692-697

2016

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A genetics-led approach defines the drug target landscape of 30 immune-related traits

Nature genetics, 2019-07, Vol.51 (7), p.1082-1091

2019

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The promise and peril of chemical probes

Nature chemical biology, 2015-08, Vol.11 (8), p.536

2015

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Target 2035: probing the human proteome

Drug discovery today, 2019-11, Vol.24 (11), p.2111-2115

2019

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Relative Wanderungsneigung von Substituenten und Stereochemie der dyotropen Ringerweiterung von β-Lactonen

Angewandte Chemie, 1997-07, Vol.109 (13-14), p.1546-1548

1997

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Different ligands-different receptor conformations: Modeling of the hERα LBD in complex with agonists and antagonists

Medicinal research reviews, 2001-11, Vol.21 (6), p.523-539

2001

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Three-Dimensional Models of Estrogen Receptor Ligand Binding Domain Complexes, Based on Related Crystal Structures and Mutational and Structure−Activity Relationship Data

Journal of medicinal chemistry, 1998-05, Vol.41 (11), p.1803-1814

1998

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Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

Drug discovery today, 2017-06, Vol.22 (6), p.896-911

2017

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ChemInform Abstract: Public‐Private Partnerships in Lead Discovery: Overview and Case Studies

ChemInform, 2016-10, Vol.47 (45), p.no-no

2016

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Binding kinetics in drug discovery - A current perspective

Frontiers in bioscience (Landmark. Print), 2017-01, Vol.22 (1), p.21

2017

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Chemical Strategies for Evaluating New Drug Targets

Target Discovery and Validation, 2020

Plowright, Alleyn T

2020

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Preclinical target validation using patient-derived cells

Nature reviews. Drug discovery, 2015-03, Vol.14 (3), p.149-150

2015

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Ligand-binding domain of estrogen receptors

Current Opinion in Biotechnology, 1999-12, Vol.10 (6), p.550-556

1999

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Target 2035 - an update on private sector contributions

RSC medicinal chemistry, 2023-06, Vol.14 (6), p.12-111

2023

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Abstract 5239: Probing the cancer epigenome: empowering target validation by open innovation

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.5239-5239

2017

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Cyclodextrine erhöhen die Oberflächenspannung und die kritische Micellbildungskonzentration von Detergenslösungen

Angewandte Chemie, 1988-03, Vol.100 (3), p.429-431

1988

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ChemInform Abstract: Different Ligands-Different Receptor Conformations: Modeling of the hERα LBD in Complex with Agonists and Antagonists

ChemInform, 2001-12, Vol.32 (52), p.no-no

2001

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ChemInform Abstract: 7α,15α-Ethano Bridged Steroids. Synthesis and Progesterone Receptor Interaction

ChemInform, 2000-01, Vol.31 (2), p.no-no

2000

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Investigation of the binding interactions of progesterone using muteins of the human progesterone receptor ligand binding domain designed on the basis of a three-dimensional protein model

Biochimica et biophysica acta, 1999-01, Vol.1429 (2), p.391-400

1999

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Cloning, purification, and crystallization of Escherichia coli cystathionine β-lyase

FEBS letters, 1996-01, Vol.379 (1), p.94-96

1996

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Three‐dimensional structure of fatty‐acid‐binding protein from bovine heart

European journal of biochemistry, 1991-07, Vol.199 (2), p.271-276

1991

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The three-dimensional structure of the bifunctional proteinase k/α-amylase inhibitor from wheat (PKI3) at 2.5 Å resolution

FEBS letters, 1991-02, Vol.279 (2), p.240-242

1991

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Donated chemical probes for open science

Public-Private Partnerships in Lead Discovery: Overview and Case Studies

A genetics-led approach defines the drug target landscape of 30 immune-related traits

The promise and peril of chemical probes

Target 2035: probing the human proteome

Relative Wanderungsneigung von Substituenten und Stereochemie der dyotropen Ringerweiterung von β-Lactonen

Different ligands-different receptor conformations: Modeling of the hERα LBD in complex with agonists and antagonists

Three-Dimensional Models of Estrogen Receptor Ligand Binding Domain Complexes, Based on Related Crystal Structures and Mutational and Structure−Activity Relationship Data

Kinetics for Drug Discovery: an industry-driven effort to target drug residence time

ChemInform Abstract: Public‐Private Partnerships in Lead Discovery: Overview and Case Studies

Binding kinetics in drug discovery - A current perspective

Chemical Strategies for Evaluating New Drug Targets

Preclinical target validation using patient-derived cells

Ligand-binding domain of estrogen receptors

Target 2035 - an update on private sector contributions

Abstract 5239: Probing the cancer epigenome: empowering target validation by open innovation

Cyclodextrine erhöhen die Oberflächenspannung und die kritische Micellbildungskonzentration von Detergenslösungen

ChemInform Abstract: Different Ligands-Different Receptor Conformations: Modeling of the hERα LBD in Complex with Agonists and Antagonists

ChemInform Abstract: 7α,15α-Ethano Bridged Steroids. Synthesis and Progesterone Receptor Interaction

Investigation of the binding interactions of progesterone using muteins of the human progesterone receptor ligand binding domain designed on the basis of a three-dimensional protein model

Cloning, purification, and crystallization of Escherichia coli cystathionine β-lyase

Three‐dimensional structure of fatty‐acid‐binding protein from bovine heart

The three-dimensional structure of the bifunctional proteinase k/α-amylase inhibitor from wheat (PKI3) at 2.5 Å resolution

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