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Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good

Human genomics, 2019-08, Vol.13 (1), p.39-39, Article 39

2019

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Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

The AAPS journal, 2017-11, Vol.20 (1), p.4-4, Article 4

2017

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Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19

Scientific reports, 2020-11, Vol.10 (1), p.20533-20533, Article 20533

2020

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Genome-wide association study identifies five risk loci for pernicious anemia

Nature communications, 2021-06, Vol.12 (1), p.3761-3761, Article 3761

2021

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Clinical characteristics and risk factors for COVID-19 infection and disease severity: A nationwide observational study in Estonia

PloS one, 2022-06, Vol.17 (6), p.e0270192-e0270192

2022

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Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

International journal of epidemiology, 2015-08, Vol.44 (4), p.1137-1147

2015

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Meta-analyses identify DNA methylation associated with kidney function and damage

Nature communications, 2021-12, Vol.12 (1), p.7174-16, Article 7174

2021

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An epigenome-wide association study of metabolic syndrome and its components

Scientific reports, 2020-11, Vol.10 (1), p.20567-20567, Article 20567

2020

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Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles

Diabetes (New York, N.Y.), 2021-08, Vol.70 (8), p.1816-1825

2021

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Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

PLoS genetics, 2017-03, Vol.13 (3), p.e1006643-e1006643

2017

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Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

Science translational medicine, 2020-06, Vol.12 (549)

2020

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Monocytes present age‐related changes in phospholipid concentration and decreased energy metabolism

Aging cell, 2020-04, Vol.19 (4), p.e13127-n/a

2020

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Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

American journal of human genetics, 2015-03, Vol.96 (3), p.377-385

2015

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Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure

Nature communications, 2023-01, Vol.14 (1), p.157-14, Article 157

2023

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Genotype-covariate interaction effects and the heritability of adult body mass index

Nature genetics, 2017-08, Vol.49 (8), p.1174-1181

2017

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Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk [S]

Journal of lipid research, 2018-10, Vol.59 (10), p.1987-2000

2018

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A distinctive DNA methylation pattern in insufficient sleep

Scientific reports, 2019-02, Vol.9 (1), p.1193, Article 1193

2019

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Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

Scientific reports, 2021-08, Vol.11 (1), p.17463-17463, Article 17463

2021

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Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Nature communications, 2022-06, Vol.13 (1), p.3200-3200, Article 3200

2022

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Sequence variation in nuclear ribosomal small subunit, internal transcribed spacer and large subunit regions of Rhizophagus irregularis and Gigaspora margarita is high and isolate-dependent

Molecular ecology, 2016-06, Vol.25 (12), p.2816-2832

2016

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Genetic and epigenetic regulation of gene expression in fetal and adult human livers

BMC genomics, 2014-10, Vol.15 (1), p.860-860, Article 860

2014

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Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

Human molecular genetics, 2015-12, Vol.24 (25), p.7445-7449

2015

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Differences in local population history at the finest level: the case of the Estonian population

European journal of human genetics : EJHG, 2020-11, Vol.28 (11), p.1580-1591

2020

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DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes

The Journal of biological chemistry, 2017-04, Vol.292 (16), p.6542-6554

2017

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Translating pharmacogenomics into clinical decisions: do not let the perfect be the enemy of the good

Pharmacogenomic Biomarkers for Improved Drug Therapy—Recent Progress and Future Developments

Longitudinal proteomic profiling reveals increased early inflammation and sustained apoptosis proteins in severe COVID-19

Genome-wide association study identifies five risk loci for pernicious anemia

Clinical characteristics and risk factors for COVID-19 infection and disease severity: A nationwide observational study in Estonia

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

Meta-analyses identify DNA methylation associated with kidney function and damage

An epigenome-wide association study of metabolic syndrome and its components

Stratification of Type 2 Diabetes by Age of Diagnosis in the UK Biobank Reveals Subgroup-Specific Genetic Associations and Causal Risk Profiles

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

Evaluating the cardiovascular safety of sclerostin inhibition using evidence from meta-analysis of clinical trials and human genetics

Monocytes present age‐related changes in phospholipid concentration and decreased energy metabolism

Dominance Genetic Variation Contributes Little to the Missing Heritability for Human Complex Traits

Genome-wide screen of otosclerosis in population biobanks: 27 loci and shared associations with skeletal structure

Genotype-covariate interaction effects and the heritability of adult body mass index

Global genetic diversity of human apolipoproteins and effects on cardiovascular disease risk [S]

A distinctive DNA methylation pattern in insufficient sleep

Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

Comprehensive genome-wide association study of different forms of hernia identifies more than 80 associated loci

Sequence variation in nuclear ribosomal small subunit, internal transcribed spacer and large subunit regions of Rhizophagus irregularis and Gigaspora margarita is high and isolate-dependent

Genetic and epigenetic regulation of gene expression in fetal and adult human livers

SARS-CoV-2 clade dynamics and their associations with hospitalisations during the first two years of the COVID-19 pandemic

Genome-wide genetic homogeneity between sexes and populations for human height and body mass index

Differences in local population history at the finest level: the case of the Estonian population

DNA breaks and chromatin structural changes enhance the transcription of autoimmune regulator target genes

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