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NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

Molecular cancer therapeutics, 2009-08, Vol.8 (8), p.2204-2210

2009

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Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

Molecular cancer therapeutics, 2007-04, Vol.6 (4), p.1357-1367

2007

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CPEB4 knockout mice exhibit normal hippocampus-related synaptic plasticity and memory

PloS one, 2013-12, Vol.8 (12), p.e84978-e84978

2013

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c-Jun Downregulation by HDAC3-Dependent Transcriptional Repression Promotes Osmotic Stress-Induced Cell Apoptosis

Molecular cell, 2007-01, Vol.25 (2), p.219-232

2007

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The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo

Cancer research (Chicago, Ill.), 2005-03, Vol.65 (5), p.1934-1940

2005

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Expression of the Receptor Tyrosine Kinase Tie2 in Neoplastic Glial Cells Is Associated with Integrin β1-Dependent Adhesion to the Extracellular Matrix

Molecular cancer research, 2006-12, Vol.4 (12), p.915-926

2006

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Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN

Oncogene, 2001-10, Vol.20 (46), p.6669-6678

2001

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Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

Annals of neurology, 2003-01, Vol.53 (1), p.109-117

2003

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Inhibition of Prostate Tumor Angiogenesis by the Tumor Suppressor CEACAM1

The Journal of biological chemistry, 2002-09, Vol.277 (38), p.35696-35702

2002

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Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma Pathway

JNCI : Journal of the National Cancer Institute, 2003-05, Vol.95 (9), p.652-660

2003

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Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus

Head & neck, 2000-07, Vol.22 (4), p.347-354

2000

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Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus

Cancer research (Chicago, Ill.), 1994-07, Vol.54 (14), p.3662-3667

1994

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Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma

Journal of neuro-oncology, 2009-09, Vol.94 (2), p.229-234

2009

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p16 Gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma

Molecular cancer therapeutics, 2003-10, Vol.2 (10), p.961-969

2003

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Adenovirus‐mediated E2F‐1 gene transfer efficiently induces apoptosis in melanoma cells

Cancer, 1999-11, Vol.86 (10), p.2021-2033

1999

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Potential efficacy of p16 gene therapy for EBV‐positive nasopharyngeal carcinoma

International journal of cancer, 2004-06, Vol.110 (3), p.452-458

2004

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Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma

Molecular cancer therapeutics, 2005-11, Vol.4 (11), p.1681-1688

2005

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Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck

Cancer research (Chicago, Ill.), 1995-07, Vol.55 (14), p.3117-3122

1995

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Expression of Human α1-Antitrypsin in Dogs After Autologous Transplantation of Retroviral Transduced Hepatocytes

Proceedings of the National Academy of Sciences - PNAS, 1992-01, Vol.89 (1), p.89-93

1992

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Restoration of endogenous wild‐type p53 activity in a glioblastoma cell line with intrinsic temperature‐sensitive p53 induces growth arrest but not apoptosis

International journal of cancer, 2001-10, Vol.94 (1), p.35-43

2001

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A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme

Journal of neuro-oncology, 2007-02, Vol.81 (3), p.271-277

2007

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Proteomic Investigation of Glioblastoma Cell Lines Treated with Wild-Type p53 and Cytotoxic Chemotherapy Demonstrates an Association between Galectin-1 and p53 Expression

Journal of proteome research, 2007-02, Vol.6 (2), p.869-875

2007

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Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis

Neuro-oncology (Charlottesville, Va.), 2008-06, Vol.10 (3), p.275-291

2008

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Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation

Cancer research (Chicago, Ill.), 2002-02, Vol.62 (4), p.1069-1076

2002

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Growth suppression of human coronary vascular smooth muscle cells by gene transfer of the transcription factor E2F-1

Circulation (New York, N.Y.), 2001-01, Vol.103 (3), p.407-414

2001

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NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas

Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo

CPEB4 knockout mice exhibit normal hippocampus-related synaptic plasticity and memory

c-Jun Downregulation by HDAC3-Dependent Transcriptional Repression Promotes Osmotic Stress-Induced Cell Apoptosis

The excitatory amino acid transporter-2 induces apoptosis and decreases glioma growth in vitro and in vivo

Expression of the Receptor Tyrosine Kinase Tie2 in Neoplastic Glial Cells Is Associated with Integrin β1-Dependent Adhesion to the Extracellular Matrix

Suppression of matrix metalloproteinase-2 gene expression and invasion in human glioma cells by MMAC/PTEN

Mechanisms underlying PTEN regulation of vascular endothelial growth factor and angiogenesis

Inhibition of Prostate Tumor Angiogenesis by the Tumor Suppressor CEACAM1

Preclinical Characterization of the Antiglioma Activity of a Tropism-Enhanced Adenovirus Targeted to the Retinoblastoma Pathway

Telomerase activity in head and neck tumors after introduction of wild-type p53, p21, p16, and E2F-1 genes by means of recombinant adenovirus

Growth suppression of human head and neck cancer cells by the introduction of a wild-type p53 gene via a recombinant adenovirus

Biomarkers of disease: cerebrospinal fluid vascular endothelial growth factor (VEGF) and stromal cell derived factor (SDF)-1 levels in patients with neoplastic meningitis (NM) due to breast cancer, lung cancer and melanoma

p16 Gene therapy: A potentially efficacious modality for nasopharyngeal carcinoma

Adenovirus‐mediated E2F‐1 gene transfer efficiently induces apoptosis in melanoma cells

Potential efficacy of p16 gene therapy for EBV‐positive nasopharyngeal carcinoma

Targeting integrin-linked kinase inhibits Akt signaling pathways and decreases tumor progression of human glioblastoma

Apoptosis induction mediated by wild-type p53 adenoviral gene transfer in squamous cell carcinoma of the head and neck

Expression of Human α1-Antitrypsin in Dogs After Autologous Transplantation of Retroviral Transduced Hepatocytes

Restoration of endogenous wild‐type p53 activity in a glioblastoma cell line with intrinsic temperature‐sensitive p53 induces growth arrest but not apoptosis

A North American brain tumor consortium (NABTC 99-04) phase II trial of temozolomide plus thalidomide for recurrent glioblastoma multiforme

Proteomic Investigation of Glioblastoma Cell Lines Treated with Wild-Type p53 and Cytotoxic Chemotherapy Demonstrates an Association between Galectin-1 and p53 Expression

Phosphorylation of Thr18 and Ser20 of p53 in Ad-p53-induced apoptosis

Apoptosis induced by adenovirus-mediated p53 gene transfer in human glioma correlates with site-specific phosphorylation

Growth suppression of human coronary vascular smooth muscle cells by gene transfer of the transcription factor E2F-1

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