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CAR-T Cells and Oncolytic Viruses: Joining Forces to Overcome the Solid Tumor Challenge

Frontiers in immunology, 2018-10, Vol.9, p.2460-2460

2018

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Oncolytic Adenoviruses in Cancer Treatment

Biomedicines, 2014-02, Vol.2 (1), p.36-49

Alemany, Ramon

2014

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Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus

Clinical cancer research, 2017-10, Vol.23 (19), p.5846-5857

2017

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A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients

Human gene therapy, 2019-03, Vol.30 (3), p.352

2019

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Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma

Clinical cancer research, 2021-02, Vol.27 (3), p.889-902

2021

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Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression

Clinical cancer research, 2015-03, Vol.21 (6), p.1406-1418

2015

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Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager

Journal for immunotherapy of cancer, 2019-01, Vol.7 (1), p.19-19, Article 19

2019

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First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors

Molecular therapy, 2020-04, Vol.28 (4), p.1033-1042

2020

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The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma

Clinical cancer research, 2016-05, Vol.22 (9), p.2217-2225

2016

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Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

Molecular therapy, 2010-07, Vol.18 (7), p.1275-1283

2010

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Effect of Transgene Location, Transcriptional Control Elements and Transgene Features in Armed Oncolytic Adenoviruses

Cancers, 2020-04, Vol.12 (4), p.1034

2020

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Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy

Cancer research (Chicago, Ill.), 2018-09, Vol.78 (17), p.4891-4901

2018

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Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

Oncoimmunology, 2023-12, Vol.12 (1), p.2261278-2261278

2023

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Joint Modelling of Survival and Emergency Medical Care Usage in Spanish Insureds Aged 65

PloS one, 2016-04, Vol.11 (4), p.e0153234-e0153234

2016

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Immunostimulatory gene therapy targeting CD40, 4-1BB and IL-2R activates DCs and stimulates antigen-specific T-cell and NK-cell responses in melanoma models

Journal of translational medicine, 2023-07, Vol.21 (1), p.506-506

2023

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Codon Usage and Adenovirus Fitness: Implications for Vaccine Development

Frontiers in microbiology, 2021-02, Vol.12, p.633946-633946

2021

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Influence of carrier cells on the clinical outcome of children with neuroblastoma treated with high dose of oncolytic adenovirus delivered in mesenchymal stem cells

Cancer letters, 2016-02, Vol.371 (2), p.161-170

2016

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Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01

PloS one, 2016-01, Vol.11 (1), p.e0147211-e0147211

2016

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The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models

Scientific reports, 2019-10, Vol.9 (1), p.14368-10, Article 14368

2019

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VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects

Journal for immunotherapy of cancer, 2021-11, Vol.9 (11), p.e003254

2021

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Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness

International journal of molecular sciences, 2020-07, Vol.21 (14), p.5158

2020

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Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation

Molecular therapy. Oncolytics, 2021-09, Vol.22, p.27-35

2021

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Blood clearance rates of adenovirus type 5 in mice

Journal of general virology, 2000-11, Vol.81 (11), p.2605-2609

2000

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CAR-T Cells and Oncolytic Viruses: Joining Forces to Overcome the Solid Tumor Challenge

Oncolytic Adenoviruses in Cancer Treatment

Shaping the Tumor Stroma and Sparking Immune Activation by CD40 and 4-1BB Signaling Induced by an Armed Oncolytic Virus

A Phase 1 Trial of Oncolytic Adenovirus ICOVIR-5 Administered Intravenously to Cutaneous and Uveal Melanoma Patients

Modification of Extracellular Matrix Enhances Oncolytic Adenovirus Immunotherapy in Glioblastoma

Safety and efficacy of VCN-01, an oncolytic adenovirus combining fiber HSG-binding domain replacement with RGD and hyaluronidase expression

Targeting the tumor stroma with an oncolytic adenovirus secreting a fibroblast activation protein-targeted bispecific T-cell engager

First-in-Human, First-in-Child Trial of Autologous MSCs Carrying the Oncolytic Virus Icovir-5 in Patients with Advanced Tumors

The Oncolytic Adenovirus VCN-01 as Therapeutic Approach Against Pediatric Osteosarcoma

Hyaluronidase Expression by an Oncolytic Adenovirus Enhances Its Intratumoral Spread and Suppresses Tumor Growth

Effect of Transgene Location, Transcriptional Control Elements and Transgene Features in Armed Oncolytic Adenoviruses

Remission of Spontaneous Canine Tumors after Systemic Cellular Viroimmunotherapy

Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

Joint Modelling of Survival and Emergency Medical Care Usage in Spanish Insureds Aged 65

Immunostimulatory gene therapy targeting CD40, 4-1BB and IL-2R activates DCs and stimulates antigen-specific T-cell and NK-cell responses in melanoma models

Codon Usage and Adenovirus Fitness: Implications for Vaccine Development

Influence of carrier cells on the clinical outcome of children with neuroblastoma treated with high dose of oncolytic adenovirus delivered in mesenchymal stem cells

Characterization of the Antiglioma Effect of the Oncolytic Adenovirus VCN-01

The oncolytic adenovirus VCN-01 promotes anti-tumor effect in primitive neuroectodermal tumor models

VCN-01 disrupts pancreatic cancer stroma and exerts antitumor effects

Arming Oncolytic Adenoviruses: Effect of Insertion Site and Splice Acceptor on Transgene Expression and Viral Fitness

Novel combinatorial therapy of oncolytic adenovirus AdV5/3-D24-ICOSL-CD40L with anti PD-1 exhibits enhanced anti-cancer efficacy through promotion of intratumoral T-cell infiltration and modulation of tumour microenvironment in mesothelioma mouse model

Hyaluronidase expression within tumors increases virotherapy efficacy and T cell accumulation

Phase I, multicenter, open-label study of intravenous VCN-01 oncolytic adenovirus with or without nab-paclitaxel plus gemcitabine in patients with advanced solid tumors

Blood clearance rates of adenovirus type 5 in mice

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