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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

PloS one, 2017-02, Vol.12 (2), p.e0171582

2017

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Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

Molecular cancer therapeutics, 2010-05, Vol.9 (5), p.1451-1460

2010

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Predicting tumor cell line response to drug pairs with deep learning

BMC bioinformatics, 2018-12, Vol.19 (Suppl 18), p.486-79, Article 486

2018

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The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3564-3576

2017

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The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (14), p.4372-4382

2013

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Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

Neuro-oncology (Charlottesville, Va.), 2011-06, Vol.13 (6), p.580-590

2011

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Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Nature reviews. Drug discovery, 2010-11, Vol.9 (11), p.843-856

2010

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Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies

BMC genomics, 2014-05, Vol.15 (1), p.393-393

2014

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Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product

Biochemical journal, 2006-06, Vol.396 (2), p.235-242

2006

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Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel

Biochemical pharmacology, 2012-05, Vol.83 (9), p.1195-1207

2012

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Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines

Biochemical and biophysical research communications, 2006-02, Vol.340 (2), p.469-475

2006

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Expression Profiling of Nuclear Receptors in the NCI60 Cancer Cell Panel Reveals Receptor-Drug and Receptor-Gene Interactions

Molecular endocrinology (Baltimore, Md.), 2010-06, Vol.24 (6), p.1287-1296

2010

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HLA class I and II genotype of the NCI-60 cell lines

Journal of translational medicine, 2005-03, Vol.3 (1), p.11-11, Article 11

2005

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Two CD95 Tumor Classes with Different Sensitivities to Antitumor Drugs

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11445-11450

2003

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A Role for REV3 in Mutagenesis During Double-Strand Break Repair in Saccharomyces cerevisiae

Genetics (Austin), 1997-11, Vol.147 (3), p.1017-1024

1997

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Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity

Molecular pharmacology, 2006-09, Vol.70 (3), p.1109-1120

2006

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Identification of Compounds that Correlate with ABCG2 Transporter Function in the National Cancer Institute Anticancer Drug Screen

Molecular pharmacology, 2009-11, Vol.76 (5), p.946-956

2009

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Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.34-40

2006

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Transcription profiling of gene expression in drug discovery and development: the NCI experience

European journal of cancer (1990), 2004-11, Vol.40 (17), p.2544-2549

2004

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Natural products and derivatives as leads to cell cycle pathway targets in cancer chemotherapy

Current cancer drug targets, 2002-12, Vol.2 (4), p.279-308

2002

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Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

Molecular cancer therapeutics, 2006-03, Vol.5 (3), p.713-722

2006

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COMPARE: a web accessible tool for investigating mechanisms of cell growth inhibition

Journal of molecular graphics & modelling, 2002, Vol.20 (4), p.297-303

2002

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Components of the Cell Death Machine and Drug Sensitivity of the National Cancer Institute Cell Line Panel

Clinical cancer research, 2004-10, Vol.10 (20), p.6807-6820

2004

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In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity

Molecular cancer therapeutics, 2004-07, Vol.3 (7), p.849-860

2004

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Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone γ-H2AX as a biomarker of DNA damage

Cancer research (Chicago, Ill.), 2007-10, Vol.67 (20), p.9971-9979

2007

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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

Predicting tumor cell line response to drug pairs with deep learning

The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies

Biological evaluation of tubulysin A: a potential anticancer and antiangiogenic natural product

Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel

Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines

Expression Profiling of Nuclear Receptors in the NCI60 Cancer Cell Panel Reveals Receptor-Drug and Receptor-Gene Interactions

HLA class I and II genotype of the NCI-60 cell lines

Two CD95 Tumor Classes with Different Sensitivities to Antitumor Drugs

A Role for REV3 in Mutagenesis During Double-Strand Break Repair in Saccharomyces cerevisiae

Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity

Identification of Compounds that Correlate with ABCG2 Transporter Function in the National Cancer Institute Anticancer Drug Screen

Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Transcription profiling of gene expression in drug discovery and development: the NCI experience

Natural products and derivatives as leads to cell cycle pathway targets in cancer chemotherapy

Spectrum of activity and molecular correlates of response to phosphatidylinositol ether lipid analogues, novel lipid-based inhibitors of Akt

COMPARE: a web accessible tool for investigating mechanisms of cell growth inhibition

Components of the Cell Death Machine and Drug Sensitivity of the National Cancer Institute Cell Line Panel

In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity

Batracylin (NSC 320846), a dual inhibitor of DNA topoisomerases I and II induces histone γ-H2AX as a biomarker of DNA damage

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