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Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

Molecular cancer therapeutics, 2010-05, Vol.9 (5), p.1451-1460

2010

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The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3564-3576

2017

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A case report of typhlitis during novel use of ropidoxuridine–capecitabine–radiotherapy for treatment-naïve rectal cancer

Cancer chemotherapy and pharmacology, 2023-08, Vol.92 (2), p.151-155

2023

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Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

Nature reviews. Drug discovery, 2010-11, Vol.9 (11), p.843-856

2010

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ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12), p.2219-2225

2022

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First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer

Journal of clinical oncology, 2017-10, Vol.35 (30), p.3391-3400

2017

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Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

Journal of clinical oncology, 2009-06, Vol.27 (16), p.2705-2711

2009

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Phase I and Pharmacology Study of Ropidoxuridine (IPdR) as Prodrug for Iododeoxyuridine-Mediated Tumor Radiosensitization in Advanced GI Cancer Undergoing Radiation

Clinical cancer research, 2019-10, Vol.25 (20), p.6035-6043

2019

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Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource

Molecular cancer therapeutics, 2023-11, Vol.22 (11), p.1270

2023

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F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Molecular cancer therapeutics, 2021-04, Vol.20 (4), p.625-631

2021

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Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas

Molecular cancer therapeutics, 2020-03, Vol.19 (3), p.731-741

2020

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Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens

Bioorganic & medicinal chemistry letters, 2019-01, Vol.29 (2), p.134-137

2019

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First-in-human phase 0 trial of oral 5-iodo-2-pyrimidinone-2'-deoxyribose in patients with advanced malignancies

Clinical cancer research, 2013-04, Vol.19 (7), p.1852-1857

2013

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Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice : Influence of sex and inhibitors

Bioorganic & medicinal chemistry, 2006, Vol.14 (1), p.62-66

2006

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Designing Phase 0 Cancer Clinical Trials

Clinical cancer research, 2008-06, Vol.14 (12), p.3675-3682

2008

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Imaging and other biomarkers in early clinical studies: one step at a time or re-engineering drug development?

Journal of clinical oncology, 2005-08, Vol.23 (24), p.5417-5419

Collins, Jerry M

2005

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Functional imaging in phase I studies: Decorations or decision making?

Journal of clinical oncology, 2003-08, Vol.21 (15), p.2807-2809

COLLINS, Jerry M

2003

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Imaging DNA synthesis with [18F]FMAU and positron emission tomography in patients with cancer

European journal of nuclear medicine and molecular imaging, 2005-01, Vol.32 (1), p.15-22

2005

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Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents: 18F-FAU, 18F-FMAU, and 18F-FLT

Cancer imaging, 2016-10, Vol.16 (1), Article 34

2016

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Pharmacogenetically driven patient selection for a first-in-human phase I trial of batracylin in patients with advanced solid tumors and lymphomas

Cancer chemotherapy and pharmacology, 2013-10, Vol.72 (4), p.917-923

2013

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A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention

European journal of nuclear medicine and molecular imaging, 2005-11, Vol.32 (11), p.1269-1275

2005

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Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors

Journal of clinical oncology, 2015-10, Vol.33 (30), p.3409-3415

2015

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Metabolism of taxol by human hepatic microsomes and liver slices : participation of cytochrome P450 3A4 and an unknown P450 enzyme

Cancer research (Chicago, Ill.), 1994-08, Vol.54 (15), p.4026-4035

1994

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Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

A case report of typhlitis during novel use of ropidoxuridine–capecitabine–radiotherapy for treatment-naïve rectal cancer

Utilizing targeted cancer therapeutic agents in combination: novel approaches and urgent requirements

ROADMAPS: An Online Database of Response Data, Dosing Regimens, and Toxicities of Approved Oncology Drugs as Single Agents to Guide Preclinical In Vivo Studies

First-in-Human Phase I Study of the Tamoxifen Metabolite Z-Endoxifen in Women With Endocrine-Refractory Metastatic Breast Cancer

Phase 0 Clinical Trial of the Poly (ADP-Ribose) Polymerase Inhibitor ABT-888 in Patients With Advanced Malignancies

Phase I and Pharmacology Study of Ropidoxuridine (IPdR) as Prodrug for Iododeoxyuridine-Mediated Tumor Radiosensitization in Advanced GI Cancer Undergoing Radiation

Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems-based Resource

F-aza-T-dCyd (NSC801845), a Novel Cytidine Analog, in Comparative Cell Culture and Xenograft Studies with the Clinical Candidates T-dCyd, F-T-dCyd, and Aza-T-dCyd

Targeting Protein Translation by Rocaglamide and Didesmethylrocaglamide to Treat MPNST and Other Sarcomas

Erythrofordins D and E, two new cassaine-type diterpenes from Erythrophleum suaveolens

Phase I trial of TRC102 (methoxyamine HCl) in combination with temozolomide in patients with relapsed solid tumors and lymphomas

First-in-human phase 0 trial of oral 5-iodo-2-pyrimidinone-2'-deoxyribose in patients with advanced malignancies

Zebularine metabolism by aldehyde oxidase in hepatic cytosol from humans, monkeys, dogs, rats, and mice : Influence of sex and inhibitors

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies

Designing Phase 0 Cancer Clinical Trials

Imaging and other biomarkers in early clinical studies: one step at a time or re-engineering drug development?

Functional imaging in phase I studies: Decorations or decision making?

Imaging DNA synthesis with [18F]FMAU and positron emission tomography in patients with cancer

Effects of capecitabine treatment on the uptake of thymidine analogs using exploratory PET imaging agents: 18F-FAU, 18F-FMAU, and 18F-FLT

Pharmacogenetically driven patient selection for a first-in-human phase I trial of batracylin in patients with advanced solid tumors and lymphomas

A simplified analysis of [18F]3'-deoxy-3'-fluorothymidine metabolism and retention

Phase I Study of Single-Agent AZD1775 (MK-1775), a Wee1 Kinase Inhibitor, in Patients With Refractory Solid Tumors

Metabolism of taxol by human hepatic microsomes and liver slices : participation of cytochrome P450 3A4 and an unknown P450 enzyme

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