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Predicting tumor cell line response to drug pairs with deep learning

BMC bioinformatics, 2018-12, Vol.19 (Suppl 18), p.486-486, Article 486

2018

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Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

PloS one, 2017-02, Vol.12 (2), p.e0171582

2017

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The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13), p.3564-3576

2017

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Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

Molecular cancer therapeutics, 2010-05, Vol.9 (5), p.1451-1460

2010

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The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

Cancer research (Chicago, Ill.), 2013-07, Vol.73 (14), p.4372-4382

2013

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Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

Neuro-oncology (Charlottesville, Va.), 2011-06, Vol.13 (6), p.580-590

2011

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Two CD95 Tumor Classes with Different Sensitivities to Antitumor Drugs

Proceedings of the National Academy of Sciences - PNAS, 2003-09, Vol.100 (20), p.11445-11450

2003

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Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity

Molecular pharmacology, 2006-09, Vol.70 (3), p.1109-1120

2006

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HLA class I and II genotype of the NCI-60 cell lines

Journal of translational medicine, 2005-03, Vol.3 (1), p.11-11, Article 11

2005

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Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines

Biochemical and biophysical research communications, 2006-02, Vol.340 (2), p.469-475

2006

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In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity

Molecular cancer therapeutics, 2004-07, Vol.3 (7), p.849-860

2004

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A Role for REV3 in Mutagenesis During Double-Strand Break Repair in Saccharomyces cerevisiae

Genetics (Austin), 1997-11, Vol.147 (3), p.1017-1024

1997

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Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Cancer research (Chicago, Ill.), 2006, Vol.66 (1), p.34-40

2006

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Transcription profiling of gene expression in drug discovery and development: the NCI experience

European journal of cancer (1990), 2004-11, Vol.40 (17), p.2544-2549

2004

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COMPARE: a web accessible tool for investigating mechanisms of cell growth inhibition

Journal of molecular graphics & modelling, 2002, Vol.20 (4), p.297-303

2002

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Abstract 2547: NCI-60 combination screening matrix of approved anticancer drugs

Cancer research (Chicago, Ill.), 2011-04, Vol.71 (8_Supplement), p.2547-2547

2011

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The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cerevisiae

Genetics (Austin), 1998-04, Vol.148 (4), p.1525-1533

1998

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Analysis of FDA-Approved Anti-Cancer Agents in the NCI60 Panel of Human Tumor Cell Lines

Molecular cancer therapeutics, 2010-05, Vol.9 (5), p.1451-1460

2010

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Abstract 1879: The exomes of the NCI60 and their implications for cancer pharmacogenomics

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.1879-1879

2012

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Transcription profiling of gene expression in drug discovery and development: the NCI experience: Gene transcription and cancer, from the genome project to practical achievements in diagnosis and therapy

European journal of cancer (1990), 2004, Vol.40 (17), p.2544-2549

2004

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EXO1 of Saccharomyces cerevisiae Functions in Mutagenesis during Double-Strand Break Repair

Annals of the New York Academy of Sciences, 1999-05, Vol.870 (1), p.375-377

1999

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The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cere

Genetics (Austin), 1998-04, Vol.148 (4), p.1525

1998

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Identification of a Polymorphic Variant Associated with HLA-DQw3 and Characterized by Specific Restriction Sites within the DQ β -Chain Gene

Proceedings of the National Academy of Sciences - PNAS, 1985-12, Vol.82 (23), p.8139-8143

1985

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Chi Enhances Heteroduplex DNA Levels During Recombination

Genetics (Austin), 1992-12, Vol.132 (4), p.879-891

1992

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Predicting tumor cell line response to drug pairs with deep learning

Phosphorylated fraction of H2AX as a measurement for DNA damage in cancer cells and potential applications of a novel assay

The National Cancer Institute ALMANAC: A Comprehensive Screening Resource for the Detection of Anticancer Drug Pairs with Enhanced Therapeutic Activity

Analysis of Food and Drug Administration-approved anticancer agents in the NCI60 panel of human tumor cell lines

The Exomes of the NCI-60 Panel: A Genomic Resource for Cancer Biology and Systems Pharmacology

Downregulation of Pdcd4 by mir-21 facilitates glioblastoma proliferation in vivo

Two CD95 Tumor Classes with Different Sensitivities to Antitumor Drugs

Bisindenoisoquinoline Bis-1,3-{(5,6-dihydro-5,11-diketo-11H-indeno[1,2-c]isoquinoline)-6-propylamino}propane bis(trifluoroacetate) (NSC 727357), a DNA Intercalator and Topoisomerase Inhibitor with Antitumor Activity

HLA class I and II genotype of the NCI-60 cell lines

Gene expression profiling of 49 human tumor xenografts from in vitro culture through multiple in vivo passages--strategies for data mining in support of therapeutic studies

Correlation of PIK3Ca mutations with gene expression and drug sensitivity in NCI-60 cell lines

In vitro evaluation of dimethane sulfonate analogues with potential alkylating activity and selective renal cell carcinoma cytotoxicity

A Role for REV3 in Mutagenesis During Double-Strand Break Repair in Saccharomyces cerevisiae

Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries

Transcription profiling of gene expression in drug discovery and development: the NCI experience

COMPARE: a web accessible tool for investigating mechanisms of cell growth inhibition

Abstract 2547: NCI-60 combination screening matrix of approved anticancer drugs

The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cerevisiae

Analysis of FDA-Approved Anti-Cancer Agents in the NCI60 Panel of Human Tumor Cell Lines

Abstract 1879: The exomes of the NCI60 and their implications for cancer pharmacogenomics

Transcription profiling of gene expression in drug discovery and development: the NCI experience: Gene transcription and cancer, from the genome project to practical achievements in diagnosis and therapy

EXO1 of Saccharomyces cerevisiae Functions in Mutagenesis during Double-Strand Break Repair

The chromosome bias of misincorporations during double-strand break repair is not altered in mismatch repair-defective strains of Saccharomyces cere

Identification of a Polymorphic Variant Associated with HLA-DQw3 and Characterized by Specific Restriction Sites within the DQ β -Chain Gene

Chi Enhances Heteroduplex DNA Levels During Recombination

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