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Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

Nature (London), 2022-01, Vol.601 (7892), p.280-284

2022

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Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons

The Journal of pharmacology and experimental therapeutics, 2017-06, Vol.361 (3), p.355-365

2017

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Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity

Biophysical journal, 2019-05, Vol.116 (9), p.1637-1649

2019

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Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule

Journal of medicinal chemistry, 2019-01, Vol.62 (1), p.306-316

2019

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Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators

Bioorganic & medicinal chemistry, 2018-07, Vol.26 (12), p.3227-3241

2018

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Boosting antibody developability through rational sequence optimization

mAbs, 2015-05, Vol.7 (3), p.505-515

2015

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Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies

Journal of medicinal chemistry, 2024-07, Vol.67 (13), p.11296-11325

2024

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Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo

ACS medicinal chemistry letters, 2017-12, Vol.8 (12), p.1252-1257

2017

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Design, Synthesis, and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor β Receptor I (TGFβRI)

Journal of medicinal chemistry, 2010-10, Vol.53 (20), p.7287-7295

2010

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Crystal-contact engineering to obtain a crystal form of the Kelch domain of human Keap1 suitable for ligand-soaking experiments

Acta crystallographica. Section F, Structural biology and crystallization communications, 2013-06, Vol.69 (6), p.592-596

2013

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Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications

Biochemical journal, 2012-10, Vol.447 (2), p.205-215

2012

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Crystal structure of the human liver X receptor beta ligand-binding domain in complex with a synthetic agonist

Journal of molecular biology, 2003-12, Vol.334 (5), p.853-861

2003

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The Mannitol Operon Repressor MtlR Belongs to a New Class of Transcription Regulators in Bacteria

The Journal of biological chemistry, 2009-12, Vol.284 (52), p.36670-36679

2009

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Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces griseus strain from Antarctica

Journal of antibiotics, 2005-05, Vol.58 (5), p.346-349

2005

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Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP

Journal of the American College of Cardiology, 2021-11, Vol.78 (19), p.1890-1900

2021

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Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP

International journal of cardiology, 2024-07, Vol.406, p.131983-131983, Article 131983

2024

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Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

Biotechnology journal, 2016-02, Vol.11 (2), p.290-297

2016

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Longitudinal analysis of systemic ventricular function and atrioventricular valve function after the Norwood procedure

European journal of cardio-thoracic surgery, 2024-03, Vol.65 (3)

2024

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Bridging patients in cardiogenic shock with a paracorporeal pulsatile biventricular assist device to heart transplantation—a single-centre experience

European journal of cardio-thoracic surgery, 2022-03, Vol.61 (4), p.942-949

2022

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PATHFINDER-CHD: prospective registry on adults with congenital heart disease, abnormal ventricular function, and/or heart failure as a foundation for establishing rehabilitative, prehabilitative, preventive, and health-promoting measures: rationale, aims, design and methods

BMC cardiovascular disorders, 2024-03, Vol.24 (1), p.181-181, Article 181

2024

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Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells

Biotechnology and bioengineering, 2016-04, Vol.113 (4), p.830-841

2016

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Bioactive adrenomedullin (bio-ADM) is associated with endothelial dysfunction in infants and children with complex congenital heart disease undergoing open-heart surgery on cardiopulmonary bypass

Clinical chemistry and laboratory medicine, 2024-02, Vol.62 (3), p.551-561

2024

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Evaluation of life cycle defective adenovirus mutants for production of adeno‐associated virus vectors

The journal of gene medicine, 2019-06, Vol.21 (6), p.e3094-n/a

2019

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Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing

Basic research in cardiology, 2022-12, Vol.117 (1), p.11, Article 11

2022

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Combined Epicardial and Transvenous Placement of an Implantable Cardioverter Defibrillator (ICD) Lead Without a Median Sternotomy in an 8-Year-Old Child

Pediatric cardiology, 2013-12, Vol.34 (8), p.1996-1997

2013

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Structural basis of inhibition of the human SGLT2–MAP17 glucose transporter

Pharmaceutical Characterization of Tropomyosin Receptor Kinase B-Agonistic Antibodies on Human Induced Pluripotent Stem (hiPS) Cell-Derived Neurons

Structure of a Therapeutic Full-Length Anti-NPRA IgG4 Antibody: Dissecting Conformational Diversity

Allosteric Activation of Striatal-Enriched Protein Tyrosine Phosphatase (STEP, PTPN5) by a Fragment-like Molecule

Discovery of tetrahydroindazoles as a novel class of potent and in vivo efficacious gamma secretase modulators

Boosting antibody developability through rational sequence optimization

Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies

Discovery of BI-2545: A Novel Autotaxin Inhibitor That Significantly Reduces LPA Levels in Vivo

Design, Synthesis, and Evaluation of Indolinones as Inhibitors of the Transforming Growth Factor β Receptor I (TGFβRI)

Crystal-contact engineering to obtain a crystal form of the Kelch domain of human Keap1 suitable for ligand-soaking experiments

Molecular structure of human GM-CSF in complex with a disease-associated anti-human GM-CSF autoantibody and its potential biological implications

Crystal structure of the human liver X receptor beta ligand-binding domain in complex with a synthetic agonist

The Mannitol Operon Repressor MtlR Belongs to a New Class of Transcription Regulators in Bacteria

Frigocyclinone, a novel angucyclinone antibiotic produced by a Streptomyces griseus strain from Antarctica

Predicting Major Adverse Cardiovascular Events in Children With Age-Adjusted NT-proBNP

Quantification of ventricular stress in univentricular hearts during early childhood using age-independent zlog-NT-proBNP

Rational plasmid design and bioprocess optimization to enhance recombinant adeno-associated virus (AAV) productivity in mammalian cells

Longitudinal analysis of systemic ventricular function and atrioventricular valve function after the Norwood procedure

Bridging patients in cardiogenic shock with a paracorporeal pulsatile biventricular assist device to heart transplantation—a single-centre experience

PATHFINDER-CHD: prospective registry on adults with congenital heart disease, abnormal ventricular function, and/or heart failure as a foundation for establishing rehabilitative, prehabilitative, preventive, and health-promoting measures: rationale, aims, design and methods

Temperature-sensitive miR-483 is a conserved regulator of recombinant protein and viral vector production in mammalian cells

Bioactive adrenomedullin (bio-ADM) is associated with endothelial dysfunction in infants and children with complex congenital heart disease undergoing open-heart surgery on cardiopulmonary bypass

Evaluation of life cycle defective adenovirus mutants for production of adeno‐associated virus vectors

Uncovering the molecular identity of cardiosphere-derived cells (CDCs) by single-cell RNA sequencing

Combined Epicardial and Transvenous Placement of an Implantable Cardioverter Defibrillator (ICD) Lead Without a Median Sternotomy in an 8-Year-Old Child

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