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Lipid-based nanoparticle formulations for small molecules and RNA drugs

Expert opinion on drug delivery, 2019-11, Vol.16 (11), p.1205-1226

2019

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Albumin displacement at the air–water interface by Tween (Polysorbate) surfactants

European biophysics journal, 2020-10, Vol.49 (7), p.533-547

2020

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High-concentration protein formulations: How high is high?

European journal of pharmaceutics and biopharmaceutics, 2017-10, Vol.119, p.353-360

2017

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Nanoparticle tracking analysis of particle size and concentration detection in suspensions of polymer and protein samples: Influence of experimental and data evaluation parameters

European journal of pharmaceutics and biopharmaceutics, 2016-07, Vol.104, p.30-41

2016

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Prediction and Reduction of the Aggregation of Monoclonal Antibodies

Journal of molecular biology, 2017-04, Vol.429 (8), p.1244-1261

2017

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Liquid-liquid phase separation of a monoclonal antibody at low ionic strength: Influence of anion charge and concentration

Biophysical chemistry, 2017-01, Vol.220, p.7-19

2017

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Thermodynamic Unfolding and Aggregation Fingerprints of Monoclonal Antibodies Using Thermal Profiling

Pharmaceutical research, 2020-04, Vol.37 (4), p.78-78, Article 78

2020

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Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

Pharmaceutical research, 2011-04, Vol.28 (4), p.920-933

2011

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Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants

Pharmaceutical research, 2021-12, Vol.38 (12), p.2065-2089

2021

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Particle Detection and Characterization for Biopharmaceutical Applications: Current Principles of Established and Alternative Techniques

Pharmaceutics, 2020-11, Vol.12 (11), p.1112

2020

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Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals

The AAPS journal, 2021-01, Vol.23 (1), p.13-13, Article 13

2021

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A Comparison between SARS-CoV-2 and Gram-Negative Bacteria-Induced Hyperinflammation and Sepsis

International journal of molecular sciences, 2023-10, Vol.24 (20), p.15169

2023

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Proteasome impairment by α-synuclein

PloS one, 2017-09, Vol.12 (9), p.e0184040-e0184040

2017

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Photo-Oxidation of Therapeutic Protein Formulations: From Radical Formation to Analytical Techniques

Pharmaceutics, 2021-12, Vol.14 (1), p.72

2021

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Comparative Stability Study of Polysorbate 20 and Polysorbate 80 Related to Oxidative Degradation

Pharmaceutics, 2023-09, Vol.15 (9), p.2332

2023

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Membranolytic activity of bile salts: influence of biological membrane properties and composition

Molecules (Basel, Switzerland), 2007-10, Vol.12 (10), p.2292-2326

2007

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Systematic Investigation of the Effect of Lyophilizate Collapse on Pharmaceutically Relevant Proteins, Part 2: Stability During Storage at Elevated Temperatures

Journal of pharmaceutical sciences, 2012-07, Vol.101 (7), p.2288-2306

2012

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Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5

Frontiers in immunology, 2018-07, Vol.9, p.1704-1704

2018

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Oxidation of polysorbates – An underestimated degradation pathway?

International journal of pharmaceutics: X, 2023-12, Vol.6, p.100202-100202, Article 100202

2023

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Concentration Effects in the Interaction of Monoclonal Antibodies (mAbs) with their Immediate Environment Characterized by EPR Spectroscopy

Molecules (Basel, Switzerland), 2019-07, Vol.24 (14), p.2528

2019

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Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

Pharmaceutics, 2022-11, Vol.14 (12), p.2575

2022

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A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein–protein interactions in protein formulation development: A case study of a therapeutic monoclonal antibody

European journal of pharmaceutics and biopharmaceutics, 2010-05, Vol.75 (1), p.16-25

2010

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Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

Biophysical journal, 2011-06, Vol.100 (11), p.2652-2661

2011

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Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping

International journal of pharmaceutics: X, 2022-12, Vol.4, p.100123-100123, Article 100123

2022

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Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain

mAbs, 2020-01, Vol.12 (1), p.1787121-1787121

2020

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Lipid-based nanoparticle formulations for small molecules and RNA drugs

Albumin displacement at the air–water interface by Tween (Polysorbate) surfactants

High-concentration protein formulations: How high is high?

Nanoparticle tracking analysis of particle size and concentration detection in suspensions of polymer and protein samples: Influence of experimental and data evaluation parameters

Prediction and Reduction of the Aggregation of Monoclonal Antibodies

Liquid-liquid phase separation of a monoclonal antibody at low ionic strength: Influence of anion charge and concentration

Thermodynamic Unfolding and Aggregation Fingerprints of Monoclonal Antibodies Using Thermal Profiling

Strategies for the Assessment of Protein Aggregates in Pharmaceutical Biotech Product Development

Expanding the toolbox for predictive parameters describing antibody stability considering thermodynamic and kinetic determinants

Particle Detection and Characterization for Biopharmaceutical Applications: Current Principles of Established and Alternative Techniques

Oil-Immersion Flow Imaging Microscopy for Quantification and Morphological Characterization of Submicron Particles in Biopharmaceuticals

A Comparison between SARS-CoV-2 and Gram-Negative Bacteria-Induced Hyperinflammation and Sepsis

Proteasome impairment by α-synuclein

Photo-Oxidation of Therapeutic Protein Formulations: From Radical Formation to Analytical Techniques

Comparative Stability Study of Polysorbate 20 and Polysorbate 80 Related to Oxidative Degradation

Membranolytic activity of bile salts: influence of biological membrane properties and composition

Systematic Investigation of the Effect of Lyophilizate Collapse on Pharmaceutically Relevant Proteins, Part 2: Stability During Storage at Elevated Temperatures

Inhibition of Lipopolysaccharide- and Lipoprotein-Induced Inflammation by Antitoxin Peptide Pep19-2.5

Oxidation of polysorbates – An underestimated degradation pathway?

Concentration Effects in the Interaction of Monoclonal Antibodies (mAbs) with their Immediate Environment Characterized by EPR Spectroscopy

Alternative Excipients for Protein Stabilization in Protein Therapeutics: Overcoming the Limitations of Polysorbates

A critical evaluation of self-interaction chromatography as a predictive tool for the assessment of protein–protein interactions in protein formulation development: A case study of a therapeutic monoclonal antibody

Biophysical Mechanisms of Endotoxin Neutralization by Cationic Amphiphilic Peptides

Characterization of radicals in polysorbate 80 using electron paramagnetic resonance (EPR) spectroscopy and spin trapping

Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain

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