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Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

Proceedings of the National Academy of Sciences - PNAS, 2009-01, Vol.106 (1), p.262-267

2009

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Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

The Journal of clinical investigation, 2000-12, Vol.106 (11), p.1311-1319

2000

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Inhibition of angiogenesis decreases alveolarization in the developing rat lung

American journal of physiology. Lung cellular and molecular physiology, 2000-09, Vol.279 (3), p.600-L607

2000

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Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy

Neoplasia (New York, N.Y.), 1999-04, Vol.1 (1), p.31-41

1999

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SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors

Cancer research (Chicago, Ill.), 2000-08, Vol.60 (15), p.4152-4160

2000

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SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

Cancer research (Chicago, Ill.), 1999, Vol.59 (1), p.99-106

1999

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Flk-1 as a target for tumor growth inhibition

Cancer research (Chicago, Ill.), 1996-08, Vol.56 (15), p.3540-3545

1996

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Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide

Clinical cancer research, 1997-07, Vol.3 (7), p.1167-1177

1997

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Targeting angiogenesis inhibits tumor infiltration and expression of the pro‐invasive protein SPARC

International journal of cancer, 2000-07, Vol.87 (2), p.261-268

2000

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The use of restriction fragment length polymorphisms and DNA duplications to study the organization of the actin multigene family in Dictyostelium discoideum

Genetics (Austin), 1986-01, Vol.112 (1), p.27-42

1986

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Measuring VEGF‐Flk‐1 Activity and Consequences of VEGF‐Flk‐1 Targeting In Vivo Using Intravital Microscopy: Clinical Applications

The oncologist (Dayton, Ohio), 2000-04, Vol.5 (S1), p.16-19

2000

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Inhibition of angiogenesis decreases alveolarization in the developing rat lung

American journal of physiology. Lung cellular and molecular physiology, 2000-09, Vol.23 (3), p.L600-L607

2000

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Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy

Neoplasia (New York, N.Y.), 1999-07, Vol.1 (2), p.183-183

1999

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Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy1

Neoplasia (New York, N.Y.), 1999-04, Vol.1 (1), p.31-41

1999

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DNA-mediated transformation system for Dictyostelium discoideum

Proceedings of the National Academy of Sciences - PNAS, 1982-12, Vol.79 (23), p.7356-7360

1982

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Inheritance of Extrachromosomal Ribosomal DNA During the Asexual Life Cycle of Dictyostelium discoideum: Examination by Use of DNA Polymorphisms

Molecular and cellular biology, 1985-02, Vol.5 (2), p.273-280

1985

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Continental and Oceanic Crust Recycling-induced Melt–Peridotite Interactions in the Trans-North China Orogen: U–Pb Dating, Hf Isotopes and Trace Elements in Zircons from Mantle Xenoliths

Journal of petrology, 2010-01, Vol.51 (1-2), p.537-571

2010

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Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (8), p.3041-3046

2008

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US Renal Data System 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States

American journal of kidney diseases, 2015-07, Vol.66 (1), p.A7-A7

2015

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Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

The New England journal of medicine, 2015-07, Vol.373 (5), p.428-437

2015

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Composition and Genesis of Depleted Mantle Peridotites from the Wadi Tayin Massif, Oman Ophiolite; Major and Trace Element Geochemistry, and Os Isotope and PGE Systematics

Journal of petrology, 2010-01, Vol.51 (1-2), p.201-227

2010

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The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis

Nephrology, dialysis, transplantation, 2011-11, Vol.26 (11), p.3458-3465

2011

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Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

Science (American Association for the Advancement of Science), 1997-05, Vol.276 (5314), p.955-960

1997

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Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment

Clinical gastroenterology and hepatology, 2024-05, Vol.22 (5), p.994-1004.e10

2024

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Two Contrasting Fabric Patterns of Olivine Observed in Garnet and Spinel Peridotite from a Mantle-derived Ultramafic Mass Enclosed in Felsic Granulite, the Moldanubian Zone, Czech Republic

Journal of petrology, 2010-01, Vol.51 (1-2), p.101-123

2010

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Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

Inhibition of VEGF receptors causes lung cell apoptosis and emphysema

Inhibition of angiogenesis decreases alveolarization in the developing rat lung

Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy

SU6668 is a potent antiangiogenic and antitumor agent that induces regression of established tumors

SU5416 is a potent and selective inhibitor of the vascular endothelial growth factor receptor (Flk-1/KDR) that inhibits tyrosine kinase catalysis, tumor vascularization, and growth of multiple tumor types

Flk-1 as a target for tumor growth inhibition

Inhibition of platelet-derived growth factor-mediated signal transduction and tumor growth by N-[4-(trifluoromethyl)-phenyl]5-methylisoxazole-4-carboxamide

Targeting angiogenesis inhibits tumor infiltration and expression of the pro‐invasive protein SPARC

The use of restriction fragment length polymorphisms and DNA duplications to study the organization of the actin multigene family in Dictyostelium discoideum

Measuring VEGF‐Flk‐1 Activity and Consequences of VEGF‐Flk‐1 Targeting In Vivo Using Intravital Microscopy: Clinical Applications

Inhibition of angiogenesis decreases alveolarization in the developing rat lung

Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy

Inhibition of Tumor Growth, Angiogenesis, and Microcirculation by the Novel Flk-1 Inhibitor SU5416 as Assessed by Intravital Multi-fluorescence Videomicroscopy1

DNA-mediated transformation system for Dictyostelium discoideum

Inheritance of Extrachromosomal Ribosomal DNA During the Asexual Life Cycle of Dictyostelium discoideum: Examination by Use of DNA Polymorphisms

Continental and Oceanic Crust Recycling-induced Melt–Peridotite Interactions in the Trans-North China Orogen: U–Pb Dating, Hf Isotopes and Trace Elements in Zircons from Mantle Xenoliths

Discovery of a Selective Inhibitor of Oncogenic B-Raf Kinase with Potent Antimelanoma Activity

US Renal Data System 2014 Annual Data Report: Epidemiology of Kidney Disease in the United States

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

Composition and Genesis of Depleted Mantle Peridotites from the Wadi Tayin Massif, Oman Ophiolite; Major and Trace Element Geochemistry, and Os Isotope and PGE Systematics

The Raf kinase inhibitor PLX5568 slows cyst proliferation in rat polycystic kidney disease but promotes renal and hepatic fibrosis

Structures of the Tyrosine Kinase Domain of Fibroblast Growth Factor Receptor in Complex with Inhibitors

Type 1 Autoimmune Pancreatitis in Europe: Clinical Profile and Response to Treatment

Two Contrasting Fabric Patterns of Olivine Observed in Garnet and Spinel Peridotite from a Mantle-derived Ultramafic Mass Enclosed in Felsic Granulite, the Moldanubian Zone, Czech Republic

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