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The FGF family: biology, pathophysiology and therapy

Nature reviews. Drug discovery, 2009-03, Vol.8 (3), p.235-253

2009

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Fibroblast growth factor signalling in osteoarthritis and cartilage repair

Nature reviews. Rheumatology, 2020-10, Vol.16 (10), p.547-564

2020

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Structural Biology of the FGF7 Subfamily

Frontiers in genetics, 2019-02, Vol.10, p.102-102

2019

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Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding

Diabetes (New York, N.Y.), 2014-12, Vol.63 (12), p.4057-4063

2014

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A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination [version 1; peer review: 4 approved]

F1000 research, 2018, Vol.7, p.872

2018

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Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia

The FASEB journal, 2018-07, Vol.32 (7), p.3752-3764

2018

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Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects

Nature communications, 2021-12, Vol.12 (1), p.7256-7256, Article 7256

2021

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Grb2, a double-edged sword of receptor tyrosine kinase signaling

Science signaling, 2012-11, Vol.5 (249), p.pe49

2012

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FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

Bone (New York, N.Y.), 2012-09, Vol.51 (3), p.621-628

2012

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FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1

American journal of physiology. Renal physiology, 2009-08, Vol.297 (2), p.F282-F291

2009

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Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.3143-3148

2012

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The parathyroid is a target organ for FGF23 in rats

The Journal of clinical investigation, 2007-12, Vol.117 (12), p.4003-4008

2007

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Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21

Cell metabolism, 2008-07, Vol.8 (1), p.77-83

2008

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FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

Proceedings of the National Academy of Sciences - PNAS, 2009-06, Vol.106 (26), p.10853-10858

2009

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FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice[S]

Journal of lipid research, 2015-08, Vol.56 (8), p.1481-1491

2015

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C-FGF23 peptide alleviates hypoferremia during acute inflammation

Haematologica (Roma), 2021-02, Vol.106 (2), p.391-403

2021

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Exploring mechanisms of FGF signalling through the lens of structural biology

Nature reviews. Molecular cell biology, 2013-03, Vol.14 (3), p.166

2013

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Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion

PLoS genetics, 2013-12, Vol.9 (12), p.e1003975

2013

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Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

Nature (London), 2014-09, Vol.513 (7518), p.436-439

2014

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FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

Nature communications, 2020-03, Vol.11 (1), p.1421-1421, Article 1421

2020

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Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

Nature chemical biology, 2020-03, Vol.16 (3), p.267

2020

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Structural basis for fibroblast growth factor receptor activation

Cytokine & growth factor reviews, 2005-04, Vol.16 (2), p.107-137

2005

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Isolated C-Terminal Tail of FGF23 Alleviates Hypophosphatemia by Inhibiting FGF23-FGFR-Klotho Complex Formation

Proceedings of the National Academy of Sciences - PNAS, 2010-01, Vol.107 (1), p.407-412

2010

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βKlotho is required for metabolic activity of fibroblast growth factor 21

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (18), p.7432-7437

2007

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The FGF family: biology, pathophysiology and therapy

Fibroblast growth factor signalling in osteoarthritis and cartilage repair

Structural Biology of the FGF7 Subfamily

Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding

A threshold model for receptor tyrosine kinase signaling specificity and cell fate determination [version 1; peer review: 4 approved]

Inhibition of fibroblast growth factor 23 (FGF23) signaling rescues renal anemia

Paracrine FGFs target skeletal muscle to exert potent anti-hyperglycemic effects

Grb2, a double-edged sword of receptor tyrosine kinase signaling

FGF23 acts directly on renal proximal tubules to induce phosphaturia through activation of the ERK1/2–SGK1 signaling pathway

FGF23 decreases renal NaPi-2a and NaPi-2c expression and induces hypophosphatemia in vivo predominantly via FGF receptor 1

Fibroblast growth factor 21 promotes bone loss by potentiating the effects of peroxisome proliferator-activated receptor γ

The parathyroid is a target organ for FGF23 in rats

Inhibition of Growth Hormone Signaling by the Fasting-Induced Hormone FGF21

FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response

FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice[S]

C-FGF23 peptide alleviates hypoferremia during acute inflammation

Exploring mechanisms of FGF signalling through the lens of structural biology

Parathyroid-specific deletion of Klotho unravels a novel calcineurin-dependent FGF23 signaling pathway that regulates PTH secretion

Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer

FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis

Molecular basis for receptor tyrosine kinase A-loop tyrosine transphosphorylation

Structural basis for fibroblast growth factor receptor activation

Isolated C-Terminal Tail of FGF23 Alleviates Hypophosphatemia by Inhibiting FGF23-FGFR-Klotho Complex Formation

βKlotho is required for metabolic activity of fibroblast growth factor 21

Tyr Phosphorylation of PDP1 Toggles Recruitment between ACAT1 and SIRT3 to Regulate the Pyruvate Dehydrogenase Complex

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